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2.
J Family Med Prim Care ; 12(8): 1713-1715, 2023 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-37767434

RESUMO

Nodular lesions can be seen in a wide range of conditions such as infections, granulomatous conditions, neutrophilic disorders, vasculitis, benign tumours and malignant conditions. These numerous aetiologies behind the occurrence of nodular lesions signify the importance of thorough work-up of the patient to diagnose the underlying reason behind the clinical condition. Erythema elevatum diutinum (EED) is a rare vasculitis with variable clinical presentation, the diagnosis of which can be challenging. Extracutaneous signs such as arthralgias, oral and penile ulcers, involvement of the eye and neuropathy have all been linked to it. Various systemic illnesses, infectious diseases, autoimmune diseases, haematological abnormalities and plasma cell dyscrasias are also associated with EED. Such extracutaneous signs in EED patients indicate that the condition may involve several organ systems. Patients with EED should be assessed for systemic manifestations to ensure focused care, since extracutaneous forms of EED may comprise deposition of circulating immune complexes.

3.
Pan Afr Med J ; 42: 208, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-36284569

RESUMO

Keratosis follicularis also called as Darier's disease, is a rare autosomal dominant cutaneous disease. It is characterized by greasy keratotic sometimes crusted red to brown papules and plaques over seborrheic areas and in flexures with nail abnormalities. It is well established that the disease begins between the ages of 6 and 20 years, with a peak onset during puberty. The disease tends to manifest early, especially with the family history of the disease. Hereby, we report a case of Darier's disease with a special interest in its late onset presentation despite having significant family history of the disease, along with clinicopathological and dermoscopic features. We also highlight the use of non-invasive investigative technique of dermoscopy as a tool to diagnose the disease.


Assuntos
Doença de Darier , Humanos , Criança , Adolescente , Adulto Jovem , Adulto , Doença de Darier/diagnóstico , Doença de Darier/genética , Doença de Darier/tratamento farmacológico , Pele/patologia , Predisposição Genética para Doença , Administração Cutânea
4.
J Clin Diagn Res ; 9(2): WD01-2, 2015 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-25859506

RESUMO

A 20-year-old female presented with raised skin lesions all over the body since birth. Clinical examination revealed multiple pigmented macules and hyperkeratotic papules seen along Blaschko's lines over the face, neck, trunk and both lower limbs. Histopathological examination revealed hyperkeratosis with moderated acanthosis and uniform pigmentation over basal zone. Systemic examination was found to be normal. A diagnosis of systematised epidermal nevus in the absence of epidermal nevus syndrome was diagnosed and the patient was asked to undergo carbon dioxide laser mediated destruction of the skin lesions. The patient was also advised to be under surveillance for late onset neurological symptoms.

5.
J Clin Diagn Res ; 7(10): 2313, 2013 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-24298515

RESUMO

A 25-year-old male was seen with complaints of itchy skin lesions over left thigh. On examination multiple annular scaly plaques with wavy borders, peripheral papules and central clearing was seen. Closer examination revealed multiple forked tracts with excoriated papules. A diagnosis of cutaneous larva migrans was made and the patient treated using T.Albendazole 400 mg twice daily for 7 days which resulted in complete clinical cure.

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