RESUMO
Renal cell carcinoma (RCC) is a highly prevalent disease worldwide with many cases being metastasised to various organs during the time of initial presentation. Metastatic RCC to the breast is a rare entity and can mimic primary breast carcinoma. In this article, we present a 63-year-old Caucasian woman presented with a breast mass that was detected by screening mammography and found to have a biopsy proven grade-II clear RCC in the breast tissue. Despite the high incidence and prevalence of primary breast cancer, metastasis from extramammary should be suspected in patients with a prior history of other cancers. In this brief literature review, we also highlight the survival benefit from surgery and close follow-up in selected group of patients with metastatic, metachronous and solitary RCC.
Assuntos
Neoplasias da Mama/diagnóstico , Carcinoma de Células Renais/diagnóstico , Neoplasias Renais/diagnóstico , Neoplasias da Mama/diagnóstico por imagem , Neoplasias da Mama/secundário , Carcinoma de Células Renais/secundário , Diagnóstico Diferencial , Feminino , Humanos , Neoplasias Renais/patologia , Mamografia , Pessoa de Meia-Idade , Metástase NeoplásicaRESUMO
Disconnected pancreatic duct syndrome is a circumferential interruption of the pancreatic duct. It usually occurs secondary to pancreatitis and carries significant diagnostic and management challenges. We present a case of disconnected pancreatic duct syndrome that represented a diagnostic and management dilemma for both medical and surgical teams. The aim of this article is to share a successful management experience of disconnected pancreatic duct syndrome with other physicians and to perform a brief but focused literature review on this challenging condition.
Assuntos
Pâncreas/patologia , Ductos Pancreáticos/patologia , Pancreatite Alcoólica/complicações , Dor Abdominal/tratamento farmacológico , Adulto , Humanos , Masculino , Necrose/etiologia , Necrose/cirurgia , Pâncreas/cirurgia , Ductos Pancreáticos/cirurgia , Equipe de Assistência ao Paciente , SíndromeRESUMO
A 56-year-old man with a history of diabetes mellitus type-2 and stage-2 chronic kidney disease secondary to diabetic nephropathy presented with an acute deterioration of kidney function. Non-invasive work-up failed to reveal the underlying aetiology for the acute kidney failure. Kidney biopsy revealed acute tubulointerstitial nephritis (ATIN) which was attributed to sitagliptin use. Only few case reports have shown this correlation. Our aim is to alert physicians and other providers of the potential effect of sitagliptin to cause ATIN with this biopsy-proven case.
