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1.
J Am Acad Orthop Surg ; 29(3): 123-130, 2021 Feb 01.
Artigo em Inglês | MEDLINE | ID: mdl-32467395

RESUMO

INTRODUCTION: Social media represents a novel platform for patient-physician interaction. Although social media utilization patterns have been analyzed in other fields, no such study has been performed in shoulder and elbow specialists. METHODS: The membership database of the society of the American Shoulder and Elbow Surgeons was queried. Online searches were performed to identify if each surgeon had professional profiles on popular social media platforms. A social media score was then calculated, defined as the number of active accounts. Statistical analysis was used to test for associations between demographics and social media utilization. RESULTS: Six hundred seventy-six surgeons were analyzed. The average social media score was 1.61. The most highly used platform was LinkedIn (61%). The least used platform was Instagram (5% active, 11% total). Female surgeons were more likely to use Instagram than men (12.5% versus 4.9%). Academic surgeons were more likely to use ResearchGate (46.5% versus 33.3%), whereas private practice surgeons were more likely to have a website (19.9% versus 11.7%). Practitioners from the South had the lowest social media utilization. CONCLUSIONS: Shoulder and elbow surgeons underuse social media. As the influence of social media continues to grow, it will be important for surgeons to implement social media within their practices.


Assuntos
Articulação do Cotovelo , Mídias Sociais , Cirurgiões , Cotovelo/cirurgia , Articulação do Cotovelo/cirurgia , Feminino , Humanos , Masculino , Ombro/cirurgia , Estados Unidos
3.
Mol Med ; 17(11-12): 1338-48, 2011.
Artigo em Inglês | MEDLINE | ID: mdl-21953418

RESUMO

An infectious etiology has been proposed for many human cancers, but rarely have specific agents been identified. One difficulty has been the need to propagate cancer cells in vitro to produce the infectious agent in detectable quantity. We hypothesized that genome amplification from small numbers of cells could be adapted to circumvent this difficulty. A patient with concomitant chronic lymphocytic leukemia (CLL) and polycythemia vera (PV) requiring therapeutic phlebotomy donated a large amount of phlebotomized blood to test this possibility. Using genome amplification methods, we identified a new isolate (BIS8-17) of torque teno virus (TTV) 10. The presence of blood isolate sequence 8-17 (BIS8-17) in the original plasma was confirmed by polymerase chain reaction (PCR), validating the approach, since TTV is a known plasma virus. Subsequent PCR testing of plasmas from additional patients showed that BIS8-17 had a similar incidence (~20%) in CLL (n = 48) or PV (n = 10) compared with healthy controls (n = 52). CLL cells do not harbor BIS8-17; PCR did not detect it in CLL peripheral blood genomic deoxyribonucleic acid (DNA) (n = 20). CLL patient clinical outcome or prognostic markers (immunoglobulin heavy chain variable region [IGHV ] mutation, CD38 or zeta-chain associated protein kinase 70 kDa [ZAP-70]) did not correlate with BIS8-17 infection. Although not causative to our knowledge, this is the first reported isolation and detection of TTV in either CLL or PV. TTV could serve as a covirus with another infectious agent or TTV variant with rearranged genetic components that contribute to disease pathogenesis. These results prove that this method identifies infectious agents and provides an experimental methodology to test correlation with disease.


Assuntos
Genoma Viral/genética , Leucemia Linfocítica Crônica de Células B/complicações , Técnicas de Amplificação de Ácido Nucleico/métodos , Policitemia Vera/complicações , Policitemia Vera/virologia , Torque teno virus/genética , Torque teno virus/isolamento & purificação , Idoso , Idoso de 80 Anos ou mais , Doadores de Sangue , Estudos de Casos e Controles , Infecções por Vírus de DNA/sangue , Infecções por Vírus de DNA/complicações , Infecções por Vírus de DNA/virologia , DNA Viral/sangue , DNA Viral/genética , Feminino , Humanos , Leucemia Linfocítica Crônica de Células B/sangue , Leucemia Linfocítica Crônica de Células B/virologia , Masculino , Pessoa de Meia-Idade , Policitemia Vera/sangue , Reprodutibilidade dos Testes
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