1.
Chem Commun (Camb)
; 47(11): 3269-71, 2011 Mar 21.
Artigo
em Inglês
| MEDLINE
| ID: mdl-21286608
RESUMO
Herein we report the functionalisation of aldehydes via hydroacylation of azodicarboxylates. A range of functionalised aldehydes are employed as the limiting reagent including chiral non-racemic aldehydes bearing α-stereocentres which are functionalised giving access to enantiomerically pure products. The resultant hydrazides can be employed as acyl donors in the synthesis of amides.