RESUMO
In this article, a case of decubitus ulcer infection caused by an extended-spectrum beta-lactamase-producing Proteus mirabilis strain, successfully treated with oral amoxicillin-clavulanate (1-month therapy) is described. This article focuses on diffusion and clinical effect of extended-spectrum beta-lactamases-producing Proteus mirabilis on treatment of gram negative lower extremity infections.
Assuntos
Antibacterianos/uso terapêutico , Farmacorresistência Bacteriana , Úlcera por Pressão/microbiologia , Infecções por Proteus/tratamento farmacológico , Proteus mirabilis , Infecção dos Ferimentos/tratamento farmacológico , beta-Lactamas/uso terapêutico , Idoso , Antibacterianos/farmacologia , Quimioterapia Combinada , Humanos , Masculino , Testes de Sensibilidade Microbiana , Infecções por Proteus/diagnóstico , Infecções por Proteus/microbiologia , Infecção dos Ferimentos/diagnóstico , Infecção dos Ferimentos/microbiologia , beta-Lactamas/farmacologiaRESUMO
We report a case in which Escherichia fergusonii, an emerging pathogen in various types of infections, was associated with cystitis in a 52-year-old woman. The offending strain was found to be multidrug resistant. Despite in vitro activity, beta-lactam treatment failed because of a lack of patient compliance with therapy. The work confirms the pathogenic potential of E. fergusonii.