RESUMO
In today's health care atmosphere, cost-containment is viewed as the most important issue. The cost of supplies is second only to the cost of salaries. However, these supplies are needed to adequately care for patients. Often, the decision on which product to buy is based solely on price and not on the performance and quality of the equipment. Nurses have a major obligation to engage in evaluating direct patient care items.
Assuntos
Equipamentos e Provisões/normas , Teste de Materiais , Serviço Hospitalar de Compras , Controle de Custos , Equipamentos e Provisões/economia , Humanos , Infusões Intravenosas/instrumentação , Recursos Humanos de EnfermagemRESUMO
The hemodynamic changes of the pulmonary vascular system in patients with mitral stenosis, has been evaluated during isometric exercise (handgrip). Heart rate, pulmonary artery sistolic, dyastolic, mean and "wedged" pressure, end-dyastolic pulmonary vascular and trans-mitralic gradient, total pulmonary resistences increase significantly. Cardiac output and pulmonary vascular bed are probably related to the tachycardia induced by the handgrip, and to the conseguent shortening of the dyastolic left ventricular filling time.
Assuntos
Contração Isométrica , Estenose da Valva Mitral/fisiopatologia , Esforço Físico , Circulação Pulmonar , Adolescente , Adulto , Feminino , Humanos , Masculino , Pessoa de Meia-IdadeRESUMO
DMSO resistant clones have been isolated from the inducible Friend leukemia cell line 5-86 both from unmutagenized cultures and following EMS mutagenesis. All the clones can grow in the presence of 1.8% DMSO and are non-inducible or poorly inducible for hemoglobin synthesis by DMSO as well as by other known inducers of Friend leukemia (FL) cells differentiation like hemin, hypoxanthine, hexamethylene bisacetamide. The clones are also defective for the expression of other properties of differentiating Friend cells like agglutinability by plant lectins and expression of the surface protein glycophorin. Some of the clones show an impaired ability to form tumors in vivo. These resistant clones might be useful for a genetic analysis of the differentiation process of Friend leukemia cells.
