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1.
Nutrients ; 12(2)2020 Feb 22.
Artigo em Inglês | MEDLINE | ID: mdl-32098332

RESUMO

Diabetes is one of the main health problems among Saharawi refugees living in Algerian camps, especially for women. As is known, diet plays an important role in the management of diabetes. However, the dietary habits of Saharawi diabetic women are unknown. Therefore, we investigated the dietary habits and established their relationship with the nutritional status and glycemic profile of such women. We recruited 65 Saharawi type II diabetic women taking orally glucose-lowering drugs only. Dietary habits were investigated using qualitative 24 h recall carried out over three non-consecutive days. Anthropometric measurements were taken and blood parameters were measured. About 80% of the women were overweight and about three out of four women had uncompensated diabetes and were insulin resistant. The Saharawi diet was found to mainly include cereals, oils, sugars, vegetables (especially onions, tomatoes, and carrots), tea, and meat. Principal component analysis identified two major dietary patterns, the first one "healthy" and the second one "unhealthy". Women in the higher tertile of adherence to the unhealthy dietary pattern had a higher homeostatic model assessment for insulin resistance (HOMA) index (b = 2.49; 95% CI: 0.41-4.57; p = 0.02) and circulating insulin (b = 4.52; 95% CI: 0.44-8.60; p = 0.03) than the women in the lowest tertile. Food policies should be oriented to improve the quality of diet of Saharawi diabetic women.


Assuntos
Glicemia/análise , Diabetes Mellitus Tipo 2/diagnóstico , Comportamento Alimentar/etnologia , Resistência à Insulina/fisiologia , Refugiados/estatística & dados numéricos , Argélia , Estudos Transversais , Diabetes Mellitus Tipo 2/sangue , Diabetes Mellitus Tipo 2/etnologia , Diabetes Mellitus Tipo 2/prevenção & controle , Comportamento Alimentar/fisiologia , Feminino , Humanos , Itália , Pessoa de Meia-Idade , Política Nutricional , Estado Nutricional/etnologia , Estado Nutricional/fisiologia , Campos de Refugiados/normas , Campos de Refugiados/estatística & dados numéricos
2.
Nutrients ; 10(10)2018 10 12.
Artigo em Inglês | MEDLINE | ID: mdl-30322091

RESUMO

The hypoglycemic effect in humans of Moringa oleifera (MO) leaf powder has, to date, been poorly investigated. We assessed the chemical composition of MO leaf powder produced at Saharawi refugee camps, its in vitro ability to inhibit α-amylase activity, and its sensory acceptability in food. We then evaluated its effect on postprandial glucose response by randomly administering, on 2 different days, a traditional meal supplemented with 20 g of MO leaf powder (MOR20), or not (control meal, CNT), to 17 Saharawi diabetics and 10 healthy subjects. Capillary glycaemia was measured immediately before the meal and then at 30 min intervals for 3 h. In the diabetic subjects the postprandial glucose response peaked earlier with MOR20 compared to CNT and with lower increments at 90, 120, and 150 min. The mean glycemic meal response with MOR20 was lower than with CNT. The healthy subjects showed no differences. Thus, MO leaf powder could be a hypoglycemic herbal drug. However, given the poor taste acceptability of the 20 g MO meal, lower doses should be evaluated. Moreover, the hypoglycemic effects of MO leaf powder should also be demonstrated by trials evaluating its long-term effects on glycaemia.


Assuntos
Glicemia/metabolismo , Diabetes Mellitus/sangue , Dieta , Hipoglicemiantes/farmacologia , Moringa oleifera , Folhas de Planta , Paladar , Adulto , África do Norte , Idoso , Argélia , Diabetes Mellitus/tratamento farmacológico , Etnicidade , Comportamento Alimentar , Feminino , Humanos , Hipoglicemiantes/uso terapêutico , Masculino , Refeições , Pessoa de Meia-Idade , Valor Nutritivo , Preparações de Plantas/administração & dosagem , Preparações de Plantas/farmacologia , Preparações de Plantas/uso terapêutico , Período Pós-Prandial , Pós , Valores de Referência , Campos de Refugiados , alfa-Amilases/antagonistas & inibidores
3.
Int J Mol Sci ; 16(8): 18923-37, 2015 Aug 12.
Artigo em Inglês | MEDLINE | ID: mdl-26274956

RESUMO

Moringa oleifera is a plant that grows in tropical and subtropical areas of the world. Its leaves are rich of nutrients and bioactive compounds. However, several differences are reported in the literature. In this article we performed a nutritional characterization and a phenolic profiling of M. oleifera leaves grown in Chad, Sahrawi refugee camps, and Haiti. In addition, we investigated the presence of salicylic and ferulic acids, two phenolic acids with pharmacological activity, whose presence in M. oleifera leaves has been scarcely investigated so far. Several differences were observed among the samples. Nevertheless, the leaves were rich in protein, minerals, and ß-carotene. Quercetin and kaempferol glycosides were the main phenolic compounds identified in the methanolic extracts. Finally, salicylic and ferulic acids were found in a concentration range of 0.14-0.33 and 6.61-9.69 mg/100 g, respectively. In conclusion, we observed some differences in terms of nutrients and phenolic compounds in M. oleifera leaves grown in different countries. Nevertheless, these leaves are a good and economical source of nutrients for tropical and sub-tropical countries. Furthermore, M. oleifera leaves are a source of flavonoids and phenolic acids, among which salicylic and ferulic acids, and therefore they could be used as nutraceutical and functional ingredients.


Assuntos
Análise de Alimentos , Moringa oleifera/química , Fenóis/química , Folhas de Planta/química , Antioxidantes/química , Chade , Cromatografia Líquida de Alta Pressão , Flavonoides/química , Cromatografia Gasosa-Espectrometria de Massas , Haiti , Extratos Vegetais/química
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