Treatment of benign paroxysmal positional vertigo of posterior semicircular canal by "Quick Liberatory Rotation Manoeuvre".

Treatment of Benign Paroxysmal Positional Vertigo is based on Semont's Liberatory Manoeuvre and on so-called "Canalith Repositioning Manoeuvres", derived from the original Epley technique. Both manoeuvres are very effective and choice of which to use depends on the experience of the physician. Semont's manoeuvre requires a quick movement of the patient in mass in the frontal plane, from the involved, to the contralateral side, which sometimes causes symptoms such as nausea or vomiting. In this technique, a secondary liberatory nystagmus is often observed as sign of the success of the manoeuvre. Repositioning manoeuvres are less fastidious because of the slow movements, but we rarely observe an objective sign of success like the liberatory nystagmus. In the present randomised trial, 300 patients with posterior canalo/cupulolithias were divided into 3 treatment groups: 100 treated by Semont Technique; 100 by a Repositioning procedure (Parnes technique); 100 by a new manoeuvre called "Quick Liberatory Rotation". Results of treatment are also compared with the natural evolution of Benign Paroxysmal Positional Vertigo observed in 18 untreated patients. Quick Liberatory Rotation is similar in the sequence of the positions of the head in the horizontal plane, to repositioning procedures, but is more like the Semont manoeuvre in the speed of the movement (about 180 degrees in less than one second). Quick Liberatory Rotation is easy to perform, well tolerated and very effective (success rate: 98% in one-three cycles). In the present investigation, a secondary liberatory nystagmus was observed in 76.1%, with a sensitivity of 81.9% in detecting patients who had completely recovered and a specificity of 43.8% in detecting failures. Effectiveness, in short and medium period (1-15 months), is similar to Semont and Parnes techniques. Authors consider Quick Liberatory Rotation, at present, a possible first choice technique in the treatment of posterior canalolithiasis.

[Pleomorphic adenoma in unusual anatomic sites: case reports and review of literature]. / Adenoma pleomorfo in sedi atipiche: casi clinici e revisione della letteratura.

Pleomorphic adenoma is the most common neoplasm of the major salivary glands, in particular of the parotid gland. Only occasionally can it be found in the cervicofacial area outside the major and minor salivary glands of the oral cavity. The present article describes three cases of pleomorphic adenoma, respectively of the external auditory canal, the nose, and the larynx. The three tumors showed no clinical or radiological signs of malignancy and were surgically excised with a suitable margin of healthy tissue. Histologically, the typical features of pleomorphic adenoma were observed in the larynx case alone. The pleomorphic adenoma of the external auditory canal evidenced an extensive apocrine glandular component; the neoplasm of the nose was itself characterized by ample proliferation of fused cells. Immunohistochemical findings revealed focal or widespread positivity to cytokeratin, S100 protein and muscle-specific actin in both the epithelial and mesenchymal components of the neoplasm. Cases of pleomorphic adenoma in sites other than the major salivary glands show clinical and radiological signs of benignity. Their histopathological identification is, however, not always straightforward; immunohistochemistry can contribute significantly to the formulation of a definitive diagnosis and to the realization of an appropriate follow-up.

[Case report: ipsilateral association of posterior and anterior canalolithiasis]. / Case-report: associazione omolaterale di canalolitiasi posteriore e anteriore.

Benign paroxysmal positional vertigo (BPPV) is the most frequently occurring dizzy syndrome. The literature provides ample descriptions of the forms determined by canalo/cupulolithiasis of the posterior canal, the most common, as well as canalo/cupulolithiasis of the horizontal canal. Descriptions of the forms of canalo/cupulolithiasis of the anterior canal are, instead, very rare and, sometimes questioned: this is fundamentally due to its superior position, which makes it a much less likely site for the accumulation of debris, both from a conceptual and practical point of view. For these reasons, the Authors feel that the presentation of this case of PPV is of particular interest. After analyzing and excluding other interpretations as less probable, they considered the syndrome as determined by the association of right posterior and anterior canalolithiasis. This form, as in the case of posterior canalolithiasis, responded to treatment with Semont's liberatory procedure.

[Sign-report: torsional nystagmus from head-shaking in patients with labyrinth lithiasis of the vertical canal]. / Sign-report: nistagmo torsionale da head-shaking test in pazienti con labirintolitiasi dei canali verticali.

The clinical picture of Positional Paroxysmal Vertigo (PPV) induced by vertical canal labyrintholithiasis has been clearly described, eliminating previous interpretations of pathogenesis of this disorder. The diagnosis of PPV is based on the well-known picture of positional paroxysmal Nystagmus. The Authors report a clinical sign which has not previously been reported in the literature: torsional Nystagmus induced by the Head-Shaking Test (HST). The Authors encoutered this sign in 30% of the cases of vertical canalolithiasis and in 50% of the cases diagnosed as vertical cupulolithiasis. This sign was also found in patients with a history of prior positional vertigo and in patients who, after treatment with release maneuver, no longer show clinical signs of positional vertigo. Such Nystagmus was not, however, found in the control group (normal subjects and patients suffering from other vestibular pathologies). In the present study the possible pathogenesis of this sign is discussed and some practical implications are considered.

[Vertical nystagmus induced by the head-shaking test: 10 cases]. / Nistagmo verticale da head-shaking test. Presentazione di dieci casi.

In cases of central and/or peripheral vestibular system asymmetry, Head-Shaking test-induced Nystagmus (H.S.-Ny) can appear after a cycle of 20 horizontal head oscillations. Four types of H.S.-Ny have been described, all of which are horizontal: 1) deficit Ny; 2) recovery Ny; 3) biphasic Ny; 4) triphasic Ny. None of these forms are specific for any given vestibular asymmetry site, whether central or peripheral. The authors report another low vertical type of H.S.-Ny found in 13 of the 1500 cases where the test was performed. Ten of these cases are discussed here. Vertical H.S.-Ny was found in 7 cases of N.M.R.-confirmed central pathologies, in 1 case of complications from epidemic parotitis and in 2 cases for which N.M.R. did not confirm the presence of an organic pathology. Vertical H.S.-Ny was often associated with other vestibular signs (Gaze-Ny, Rebound Ny, variable direction Ny, down-beat positional Ny, labyrinthine hyper reflexia). The authors consider this form of nystagmus a simple, easily determined signal of great importance in diagnosing the presence of a central, tronco-encephalic and cerebellar pathologies.

[Treatment of a positive Rhesus D neonate born of a mother with idiopathic thrombopenic purpura with anti-D immunoglobulins (Rh O)]. / Traitement d'un nouveau-né Rhésus D positif né de mère atteinte d'un purpura thrombopénique idiopathique par immunoglobulines anti-D (Rh O).

A Rhesus D positive infant, born at 37 weeks of gestational age, admitted for neonatal passive immune thrombocytopenia was given 3 intravenous anti-Rhesus D immunoglobulin infusions at 3 weeks of age. This thrombocytopenia which had not responded to conventional therapy improved after the third of anti-Rhesus D immunoglobulin infusion, but the efficacy of this treatment could not be proven in this case report. However, the tolerance was good. No side-effects (jaundice, severe anemia) were observed.