Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 20 de 20
Filtrar
1.
Mali Med ; 37(3): 74-76, 2022.
Artigo em Francês | MEDLINE | ID: mdl-38514951

RESUMO

Conjunctival tumors are common in tropical areas, where exposure to ultraviolet radiation is high and almost permanent. Malignant tumors are quite rare and the most represented is conjunctival squamous cell carcinoma. We report two cases of invasive squamous cell carcinoma of the conjunctiva received in the ophthalmology department of the Sominé Dolo hospital in Mopti, Mali. The patients were 25 and 51 years old, living in a rural desert area exposed to sunlight and dust. They presented with a mass developed in the area of the palpebral fissure, invading the cornea and preventing palpebral occlusion. The mass was raised, multi-lobulated, well circumscribed, pearly white in color and papillomatous in appearance with dilation of the feeder vessels. A wide surgical excision at 4 - 5 mm from the healthy tissue edges was performed with anatomopathological examination of the specimen, which confirmed a mature and invasive differentiated squamous cell carcinoma of the conjunctiva. The extension workup and HIV serology were negative. The evolution was favorable in the medium term without recurrence.


Les tumeurs conjonctivales sont fréquentes dans les zones tropicales,où l'exposition aux rayons ultraviolets est forte et quasi permanente. Les tumeurs malignes sont assez rares et la plus représentée est le carcinome épidermoïde de la conjonctive.Nous rapportons deux cas de carcinome épidermoïde invasif de la conjonctive reçus dans le service d'ophtalmologie de l'hôpital Sominé Dolo de Mopti au Mali. Il s'agissait de deux patientes de 25 et 51 ans, vivant en zone rurale et désertique exposées aux rayons solaires et à la poussière. Elles présentaient une masse développée dans l'aire de la fente palpébrale, envahissant la cornée et empêchant l'occlusion palpébrale. La masse était en relief, multi lobulée, bien circonscrite, de couleur blanc nacré et d'aspect papillomateux avec une dilatation des vaisseaux nourriciers. Une exérèse chirurgicale large à 4 - 5 mm des berges de tissu sain a été réalisée avec examen anatomopathologique de la pièce qui a confirmé un carcinome épidermoïde différencié mature et invasif de la conjonctive. Le bilan d'extension et la sérologie HIV étaient négatifs. L'évolution était favorable à moyen terme sans récidive.

2.
Mali Médical ; 28(3): 74-76, 30/09/2022. Figures
Artigo em Francês | AIM (África) | ID: biblio-1397780

RESUMO

Les tumeurs conjonctivales sont fréquentes dans les zones tropicales,où l'exposition aux rayons ultraviolets est forte et quasi permanente. Les tumeurs malignes sont assez rares et la plus représentée est le carcinome épidermoïde de la conjonctive.Nous rapportons deux cas de carcinome épidermoïde invasif de la conjonctive reçus dans le service d'ophtalmologie de l'hôpital Sominé Dolo de Mopti au Mali. Il s'agissait de deux patientes de 25 et 51 ans, vivant en zone rurale et désertique exposées aux rayons solaires et à la poussière. Elles présentaient une masse développée dans l'aire de la fente palpébrale, envahissant la cornée et empêchant l'occlusion palpébrale. La masse était en relief, multi lobulée, bien circonscrite, de couleur blanc nacré et d'aspect papillomateux avec une dilatation des vaisseaux nourriciers. Une exérèse chirurgicale large à 4 - 5 mm des berges de tissu sain a été réalisée avec examen anatomopathologique de la pièce qui a confirmé un carcinome épidermoïde différencié mature et invasif de la conjonctive. Le bilan d'extension et la sérologie HIV étaient négatifs. L'évolution était favorable à moyen terme sans récidive


Conjunctival tumors are common in tropical areas, where exposure to ultraviolet radiation is high and almost permanent. Malignant tumors are quite rare and the most represented is conjunctival squamous cell carcinoma. We report two cases of invasive squamous cell carcinoma of the conjunctiva received in the ophthalmology department of the Sominé Dolo hospital in Mopti, Mali. The patients were 25 and 51 years old, living in a rural desert area exposed to sunlight and dust. They presented with a mass developed in the area of the palpebral fissure, invading the cornea and preventing palpebral occlusion. The mass was raised, multi-lobulated, well circumscribed, pearly white in color and papillomatous in appearance with dilation of the feeder vessels. A wide surgical excision at 4 - 5 mm from the healthy tissue edges was performed with anatomopathological examination of the specimen, which confirmed a mature and invasive differentiated squamous cell carcinoma of the conjunctiva. The extension workup and HIV serology were negative. The evolution was favorable in the medium term without recurrence


Assuntos
Carcinoma , Doenças da Túnica Conjuntiva , Exposição Ambiental , Carcinoma de Células Escamosas de Cabeça e Pescoço , Reparo do DNA , Fator de Proteção Solar
3.
J Fr Ophtalmol ; 44(2): 145-150, 2021 Feb.
Artigo em Francês | MEDLINE | ID: mdl-33413987

RESUMO

INTRODUCTION: During the COVID-19 pandemic, we have witnessed a world-wide lock-down of the population. This government action combined with the application of social distancing should in principle reduce the frequency of occurrence of ocular injuries. The goal of our work is to try to understand the circumstances of the occurrence of ocular injuries at the IOTA Teaching Hospital during the lock-down period of the COVID-19 health crisis. METHODOLOGY: This was a cross-sectional, descriptive study. The data were collected prospectively. Our study covered the period from March to May 2020. All consenting patients seen at the IOTA Teaching Hospital for ocular trauma regardless of gender, age, circumstances in which the trauma occurred or the nature of the injuries were included by non-probability sampling. Excluded from the study were patients who did not consent or who consulted for a non-traumatic ophthalmologic condition. RESULTS: There were a total of 138 cases, of which 84 were male and 54 female, for a gender ratio of M/F=1.5. Children aged 0 to 5 years represented more than 3/4 (79.14%) of our sample. Trauma occurred in 45.83% of cases during leisure activities and 3.60% of cases involved domestic violence. DISCUSSION: According to the authors, measures aimed at limiting public movement, particularly the curfews introduced by the Malian government to contain the spread of the COVID-19 pandemic, may actually result in trauma. CONCLUSION: Raising public awareness of the social and psychological consequences of lock-down through audiovisual means might significantly reduce the frequency of these ocular traumas.


Assuntos
COVID-19/epidemiologia , Traumatismos Oculares/epidemiologia , Pandemias , SARS-CoV-2 , Adolescente , Adulto , Distribuição por Idade , COVID-19/prevenção & controle , Criança , Pré-Escolar , Estudos Transversais , Traumatismos Oculares/etiologia , Traumatismos Oculares/patologia , Feminino , Humanos , Lactente , Masculino , Pessoa de Meia-Idade , Fotografação , Estudos Prospectivos , Quarentena , Distribuição por Sexo , Adulto Jovem
4.
Environ Technol ; 41(18): 2314-2336, 2020 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-30640568

RESUMO

This paper studies original protocols of rapid PES/PVP membrane NaOCl degradation allowing at reaching ageing states that are representative of industrial ageing. The long term objective is to propose basis for further fundamental studies aiming at the improvement of the impact of membrane ageing on behaviour in UF (fouling and cleaning mastering). The key of several protocols is the use of ageing acceleration thanks to microwave irradiation, either continuous or pulsed ones, that can be further associated (or not) with short ageing time in UF conditions. To evaluate the representativeness of obtained aged membranes, comparisons are achieved between pristine, voluntary laboratory aged membranes and an industrial membrane at the end of its service-life. Several physico-chemical analyses were used (ATR-FTIR, SEM-EDX, contact angle, SEC-HPLC). Evaluation of UF performances were made in UF of a model protein (Lysozyme, 14,300 g.mol-1). Finally, the proof of concept is done that conditions using MW exist to reach ageing state representative of industrial ageing.


Assuntos
Ultrafiltração , Purificação da Água , Membranas Artificiais , Micro-Ondas
5.
J Fr Ophtalmol ; 43(1): 31-34, 2020 Jan.
Artigo em Francês | MEDLINE | ID: mdl-31761318

RESUMO

PURPOSE: To study the topography of retinal breaks and their agreement with Lincoff's rules. MATERIALS AND METHODS: We performed a retrospective descriptive study of patients with recent rhegmatogenous retinal detachments followed on the ophthalmology service of Abass Ndao Hospital from January 2006 through December 2016. Patients with no prior retinal treatment were included. RESULTS: Over 11 years, we reviewed 97 patients with 107 eyes with retinal detachments. The mean age of our patients was 51.7 years, range 23-79 years. There were 69 male patients, for a male:female ratio of 2.46. Refraction revealed that 38.1% of patients were myopes. Fourteen percent (14%) of patients had experienced trauma to the eye with the detachment. The right eye was involved in 54.6% of patients. The onset was insidious in 54.6% of cases and sudden in 23.7% of cases. All patients had decreased visual acuity, associated with a scotoma in 26.8% of cases. Visual acuity was decreased to light perception through 7/10. In 64.9% of cases, Lincoff's rules were observed. DISCUSSION: Lincoff's rules are still relevant for localization of the breaks in retinal detachments. CONCLUSION: Diagnosis of a retinal detachment is an essential step, since it determines the treatment. Lincoff's rules still have a role in finding the retinal break in retinal detachments.


Assuntos
Técnicas de Diagnóstico Oftalmológico , Descolamento Retiniano/diagnóstico , Perfurações Retinianas/diagnóstico , Adulto , Idoso , Topografia da Córnea/métodos , Estudos Transversais , Técnicas de Diagnóstico Oftalmológico/normas , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Miopia/complicações , Miopia/diagnóstico , Miopia/patologia , Reprodutibilidade dos Testes , Descolamento Retiniano/complicações , Descolamento Retiniano/patologia , Perfurações Retinianas/complicações , Perfurações Retinianas/patologia , Estudos Retrospectivos , Testes Visuais , Adulto Jovem
6.
J Fr Ophtalmol ; 42(2): 133-137, 2019 Feb.
Artigo em Francês | MEDLINE | ID: mdl-30709563

RESUMO

PURPOSE: To appreciate the epidemiological characteristics and to show the therapeutic aspects of the giant retinal tears. PATIENTS AND METHODS: We conducted a retrospective study from January 2014 to June 2017 on subjects with giant retinal tears. Patients with media opacities limiting examination were excluded. RESULTS: We identified 17 cases of giant retinal tears. The frequency of detachments related to a giant retinal tear was 17% compared to all retinal tears. The mean age was 50.75 years with a sex ratio (M/F) of 6.5. We found three cases of high myopia, one case of hyperopia and four trauma cases. All patients had a decrease in visual acuity. The average time to consultation was four weeks. The mean intraocular pressure was 8mmHg. The tear was found in the left eye in eight cases and in the right eye in five cases; two cases were bilateral. We performed intraocular surgery in five eyes and laser in four eyes. We achieved anatomical reattachment and functional improvement in all operated patients. COMMENTS AND CONCLUSION: The prognosis of a giant retinal tear remains guarded, especially if patients are seen and treated late. Laser photocoagulation of giant tears remains effective, especially in cases of early diagnosis.


Assuntos
Perfurações Retinianas/epidemiologia , Perfurações Retinianas/terapia , Adulto , Feminino , Humanos , Incidência , Masculino , Pessoa de Meia-Idade , Prognóstico , Descolamento Retiniano/diagnóstico , Descolamento Retiniano/epidemiologia , Descolamento Retiniano/terapia , Perfurações Retinianas/diagnóstico , Perfurações Retinianas/patologia , Estudos Retrospectivos , Senegal/epidemiologia , Índice de Gravidade de Doença , Acuidade Visual , Vitrectomia/estatística & dados numéricos
7.
J Fr Ophtalmol ; 42(2): 170-176, 2019 Feb.
Artigo em Francês | MEDLINE | ID: mdl-30683536

RESUMO

INTRODUCTION: Our goal was to evaluate the normal macular thickness in Blacks by OCT and to determine socio-demographic and clinical parameters which may influence it. MATERIALS AND METHODS: This was a multicenter, prospective, descriptive study over 6 months. It included Black adults followed in the ophthalmology departments of Abass Ndao and Aristide-Le-Dantec hospitals in Dakar. Included subjects had corrected visual acuity of 10/10 (0 logMAR) and P2 (+0.1 logMAR), clear ocular media, and no retinal abnormalities. We used the Topcon 3D 2000 OCT to measure the central thicknesses of the cornea (CT) and of the macula (MT), and cup to disc ratio (C/D) in each eye. Socio-demographic, clinical and tomographic data were collected on a survey form and correlated to the MT. The analysis was carried out by the Epi info 7 software. We used the Chi2 comparison test with a P value˂0.05. RESULTS: One hundred and nine patients were included. The mean age was 27.39 years with a male/female ratio of 0.65. The subjects were emmetropic in 54.13% of cases. The mean CT was 519.97µm, the mean C/D was 0.23, and the mean MT was 264.35µm. The P-value (P) was greater than or equal to 0.1 for all the factors studied. CONCLUSION: MT in our study was lower than that of Whites, and the various parameters studied did not demonstrate a statistically significant influence on MT.


Assuntos
Macula Lutea/diagnóstico por imagem , Tomografia de Coerência Óptica , Adolescente , Adulto , População Negra/estatística & dados numéricos , Estudos Transversais , Feminino , Humanos , Macula Lutea/patologia , Masculino , Tamanho do Órgão , Senegal/epidemiologia , Fatores Socioeconômicos , Adulto Jovem
8.
J Fr Ophtalmol ; 41(6): 507-512, 2018 Jun.
Artigo em Francês | MEDLINE | ID: mdl-29903585

RESUMO

INTRODUCTION: In Senegal, 10% of the population are said to be carriers of hemoglobin S, the most widespread hemoglobinopathy in the world. It is responsible for potentially blinding ophthalmological manifestations. Few practitioners refer patients for ophthalmologic screening. The goal of our study was to assess the level of knowledge of practitioners of the blinding ocular lesions of sickle cell disease. MATERIALS AND METHODS: A cross-sectional prospective study was carried out over five months. It included Dakar university hospital practitioners aside from ophthalmologists. On the survey form, each practitioner specified his or her specialty and responded to eight questions regarding sickle cell patients seen in consultation, knowledge of the blinding lesions related to the disease, and ocular monitoring for blinding systemic diseases. The practitioners were divided into three groups: department of medicine and medical specialties (group I), surgery and surgical specialties (group II), and biology and functional testing (group III). The descriptive analysis was done with the EPI-INFO software version 6.04. RESULTS: The participation rate was 45.88%. Group I represented 45.29% of the sample, Group II 35.85% and Group III 18.86%. In all, 87.73% of practitioners saw sickle cell patients in consultation, 75.47% were aware of ocular involvement related to sickle cell disease, and 58.49% were aware of blinding lesions. 94.62% of practitioners saw sickle cell disease patients without systematically recommending ophthalmological consultation. CONCLUSION: Practitioners' level of knowledge of the blinding ocular lesions of sickle cell disease is considered to be low.


Assuntos
Anemia Falciforme/complicações , Cegueira/etiologia , Percepção , Médicos , Anemia Falciforme/epidemiologia , Anemia Falciforme/psicologia , Atitude do Pessoal de Saúde , Cegueira/epidemiologia , Cegueira/psicologia , Estudos Transversais , Hospitais Universitários , Humanos , Médicos/psicologia , Médicos/estatística & dados numéricos , Senegal/epidemiologia
9.
J Fr Ophtalmol ; 40(8): 629-635, 2017 Oct.
Artigo em Francês | MEDLINE | ID: mdl-28882390

RESUMO

INTRODUCTION: Our goal is to assess the Quality of Life (QL) of our patients after cataract surgery. MATERIALS AND METHODS: We performed a multicenter prospective study from July 2012 to December 2013 including patients undergoing cataract surgery, aged 18 and older. A survey sheet with sociodemographic data, clinical data and QL survey (VF-14) was given to each patient after surgery at day 7 (D7), one month (M1) and two months (M2) postoperatively. The final score was obtained by the following formula: QL=V (%)=(F __/__ C)×25. The data analysis was performed using SPSS software. RESULTS: A total of 100 patients were included, 56 men, and 61 years was the mean age. The mean QL score was 29.86% at D7, 73.97% at M1 and 81.21% at M2. Subjects between 18 and 30 years of age had a score of 90.15% vs. 82.52% at M2 for older patients. After optical correction, the quality of life scores increased from 83.22% at D7 to 93.18% at M2. Patients who did not have functional signs had a QL score of 83.94%. Anxious patients had a QL score of 44% at D7, 61.23% at M1 and 52.67% at M2. CONCLUSION: Good surgical outcomes require, in addition to clinical success, good quality of life. Several factors may influence this quality of life.


Assuntos
Extração de Catarata/reabilitação , Qualidade de Vida , Adulto , Idoso , Idoso de 80 Anos ou mais , Extração de Catarata/psicologia , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Período Pós-Operatório , Inquéritos e Questionários , Visão Ocular/fisiologia , Acuidade Visual/fisiologia
10.
J Fr Ophtalmol ; 40(8): 676-680, 2017 Oct.
Artigo em Francês | MEDLINE | ID: mdl-28893456

RESUMO

PURPOSE: The purpose was to record the causes of leukocoria among children under 10years of age and to determine the proportion of rare causes of leukocoria. PATIENTS AND METHODS: This retrospective study was conducted over a period of ten years, from January 1, 2004 to December 31, 2013, in patients under 10years of age who were referred for leukocoria. RESULTS: Leukocoria represented one of the ten reasons for consultation among children under 10years of age. The mean age of our patients was 42.5months. In 76 % of cases, the leukocoria patients were children under 6years of age. Male patients were affected more commonly, with a sex-ratio of 1.5. Patients coming from Dakar and its suburbs represented two thirds of the total. Bilateral involvement represented 53.7 % of the total. Cataracts were responsible for 74.3 % of cases, retinoblastoma 20.58 %, retinal detachment 0.96 %, retinopathy of prematurity 0.96 %, pupillary membrane persistence 0.96 %, persistent hyperplastic primary vitreous 0.64 %, endophthalmitis 0.64 %, optic nerve coloboma 0.32 %, iris heterochromia 0.32 % and ametropia 0.32 %. DISCUSSION: The total percentage of rare causes was 5.12 % in our study, including one case of hyperopia. These etiologies, although rare, do exist. CONCLUSION: Rare causes of leukocoria require special attention. The discovery of leukocoria necessitates rigorous etiological work-up. Ametropia must be a diagnosis of exclusion.


Assuntos
Distúrbios Pupilares/diagnóstico , Distúrbios Pupilares/epidemiologia , Distúrbios Pupilares/etiologia , Catarata/complicações , Catarata/diagnóstico , Catarata/epidemiologia , Criança , Pré-Escolar , Diagnóstico Diferencial , Feminino , Humanos , Incidência , Lactente , Doenças da Íris/diagnóstico , Doenças da Íris/epidemiologia , Masculino , Vítreo Primário Hiperplásico Persistente/complicações , Vítreo Primário Hiperplásico Persistente/diagnóstico , Vítreo Primário Hiperplásico Persistente/epidemiologia , Transtornos da Pigmentação/diagnóstico , Transtornos da Pigmentação/epidemiologia , Neoplasias da Retina/complicações , Neoplasias da Retina/diagnóstico , Neoplasias da Retina/epidemiologia , Retinoblastoma/complicações , Retinoblastoma/diagnóstico , Retinoblastoma/epidemiologia , Estudos Retrospectivos
11.
J Fr Ophtalmol ; 40(2): 110-114, 2017 Feb.
Artigo em Francês | MEDLINE | ID: mdl-28087083

RESUMO

PURPOSE: To report the clinical investigation of isolated microspherophakia involving a Senegalese family in order to appreciate its functional impact. OBSERVATIONS: This is a rural family comprised of 7 members. The sibship included three girls and two boys. One of the girls, who lived in a distant zone, was unable to be examined. Of all the examined members of the family, only the father was unaffected by the illness. There was no consanguinity. The general medical examination was normal. The best-corrected visual acuity (VA) for the girls was 2/10. For one of the boys, BCVA was 8/10 for both eyes, and for the other, BCVA was 10/10 for the right eye and 8/10 for the left eye. The mother's VA was 10/10 and P2 without correction. Myopia and astigmatism were present in the 4 children of the sibship. During the examination, we noted the presence of small crystalline lenses, which were very round and presented an abnormal visibility of the lens equator and zonular fibers. The diagnosis of microspherophakia was confirmed by measurement of the lens diameters by ultrasound biomicroscopy. Complications were present in the girls, including pupillary block glaucoma and amblyopia for the elder, and retinal degeneration and amblyopia for the younger daughter. The elder daughter was managed medically with glaucoma drops. The younger daughter received optical correction and a prophylactic Argon LASER treatment. The two boys received optical correction. No treatment was recommended for the mother. CONCLUSION: Microspherophakia is a rare condition. Some serious complications can lead to amblyopia. A better multidisciplinary evaluation would allow for early detection and a better prognosis.


Assuntos
Doenças da Córnea/patologia , Ectopia do Cristalino/patologia , Glaucoma/patologia , Iris/anormalidades , Adolescente , Adulto , Criança , Doenças da Córnea/genética , Ectopia do Cristalino/genética , Família , Feminino , Glaucoma/genética , Humanos , Iris/patologia , Masculino , Senegal
12.
Clin Immunol ; 159(1): 1-12, 2015 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-25889622

RESUMO

Characterizing perturbations in the immune response to tuberculosis in HIV can develop insights into the pathogenesis of coinfection. HIV+ TB+ and TB monoinfected (TB+) subjects recruited from clinics in Bamako prior to initiation of TB treatment were evaluated at time-points following initiation of therapy. Flow cytometry assessed CD4+/CD8+ T cell subsets and activation markers CD38/HLA-DR. Antigen specific responses to TB proteins were assessed by intracellular cytokine detection and proliferation. HIV+ TB+ subjects had significantly higher markers of immune activation in the CD4+ and CD8+ T cells compared to TB+ subjects. HIV+ TB+ had lower numbers of TB-specific CD4+ T cells at baseline. Plasma IFNγ levels were similar between HIV+ TB+ and TB+ subjects. No differences were observed in in-vitro proliferative capacity to TB antigens between HIV+ TB+ and TB+ subjects. Subjects with HIV+ TB+ coinfection demonstrate in vivo expansion of TB-specific CD4+ T cells. Immunodeficiency associated with CD4+ T cell depletion may be less significant compared to immunosuppression associated with HIV viremia or untreated TB infection.


Assuntos
Linfócitos T CD4-Positivos/imunologia , Linfócitos T CD8-Positivos/imunologia , Coinfecção/imunologia , Infecções por HIV/imunologia , Tuberculose Pulmonar/imunologia , ADP-Ribosil Ciclase 1/imunologia , Adulto , Fármacos Anti-HIV/uso terapêutico , Antígenos de Bactérias/imunologia , Antituberculosos/uso terapêutico , Proliferação de Células , Coinfecção/tratamento farmacológico , Feminino , Citometria de Fluxo , Infecções por HIV/tratamento farmacológico , Antígenos HLA-DR/imunologia , Humanos , Interferon gama/imunologia , Interleucina-10/imunologia , Interleucina-12/imunologia , Interleucina-13/imunologia , Interleucina-2/imunologia , Ativação Linfocitária/imunologia , Masculino , Tuberculose Pulmonar/tratamento farmacológico , Fator de Necrose Tumoral alfa/imunologia
13.
Mali méd. (En ligne) ; 30(1): 14-18, 2015.
Artigo em Francês | AIM (África) | ID: biblio-1265685

RESUMO

Introduction :Le paludisme est l'un des rares fleaux de sante publique qui ait traverse les siecles sans perdre de son activite. Il sevit dans la ceinture de pauvrete du monde et represente la maladie parasitaire la plus repandue dans le monde intertropical. La region afro tropicale; qui ne compte que 8 de la population supporte le plus lourd fardeau du paludisme avec 80 90 des cas (200 a 280 millions) dont 90dus a plasmodium falciparum Objectif: L'objectif de cette etude etait d'etudier les sequelles du neuropaludisme dans le service de pediatrie. Materiel et Methode. De Fevrier 2009 a Janvier 2010; nous avons realise une etude portant sur les sequelles du neuropaludisme dans le service de pediatrie du CHU Gabriel Toure. L'etude concernait les enfants de 0 a 15 ans; hospitalises et gardes des sequelles neurologiques apres un neuropaludisme. Resultats: 2230 patients ont ete admis pour paludisme dont 1320 hospitalises pour neuropaludisme. Nous avons recense 92 cas (6;97) de sequelles neurologiques .Il y avait 57 contre 35 filles soit un sexe ratio de 1;63.La tranche d'age de 0 a 5 ans etait la plus representee; soit 67;39.L'hypotonie axiale etait la sequelle. La plus frequemment rencontree (65;22).Elle etait associee a l'aphasie chez trente sept patients (40;22) et a l'hypertonie peripherique chez dix-huit patients (19;57). Sept patients (7;61) sont devenus epileptiques et six (6;52) ont presente une dystonie. La recuperation des sequelles a ete de 50 a court terme et de 73;9


Assuntos
Malária Cerebral , Manifestações Neurológicas , Pediatria
14.
J Fr Ophtalmol ; 37(9): 689-94, 2014 Nov.
Artigo em Francês | MEDLINE | ID: mdl-25199485

RESUMO

INTRODUCTION: Cycloplegia allows for an objective refraction in children. Atropine is the gold standard but causes prolonged blurred vision. Cyclopentolate is less effective but less disabling. Tropicamide is a weak cycloplegic. The purpose of this study was to evaluate a cyclopentolate and tropicamide combination (CTA) versus atropine for refraction in black children. MATERIALS AND METHODS: We performed a prospective study between October 2011 and July 2012 on all children seen in consultation. Objective refraction was performed after cycloplegia with cyclopentolate 0.5% combined with tropicamide 0.5%, and then after cycloplegia with atropine. RESULTS: Thirty-three patients were recruited, 14 boys and 19 girls. The average age was 9.9 years. The mean age of the patients was 9.9 years. Astigmatism was found in 96.9% of cases. It was 1.34±1.32 diopters with CTA and 1.35±1.22 diopters with atropine. The mean axis was 98.15 and 99.8, respectively. Hyperopia and myopia were found in 39 and 27 eyes, respectively with ACT (average 1.73 and 5.37 diopters), and in 41 and 19 eyes with atropine (average 2.06 and 6.11 diopters). DISCUSSION: There is a good correlation of results with regards to cylindrical and spherical refractive error between the two protocols. Atropine is the best cycloplegic, however ACT provides reliable results. CONCLUSION: The cyclopentolate-tropicamide combination is satisfactory for routine cycloplegia in children.


Assuntos
Ciclopentolato/uso terapêutico , Midriáticos/uso terapêutico , Erros de Refração/tratamento farmacológico , Tropicamida/uso terapêutico , Adolescente , Atropina/uso terapêutico , População Negra , Criança , Pré-Escolar , Quimioterapia Combinada , Feminino , Humanos , Masculino , Estudos Prospectivos
15.
Artigo em Inglês | MEDLINE | ID: mdl-19182212

RESUMO

OBJECTIVES: A cross-sectional study was conducted to assess the prevalence of human immunodeficiency virus (HIV), hepatitis B virus (HBV), and their coinfection among blood donors at the National Blood Transfusion Center in Bamako, Mali, from November 2001 to July 2002. METHODS: Enzyme-linked immunosorbent assay techniques with reagents from Bio-Rad (France) were used to test the blood samples. RESULTS: 11,592 blood donors were tested for HIV and HBV surface antigens. The prevalence of HIV was 4.5% and the prevalence of HBV was 14.9%. The HIV/HBV coinfection rate was only 1.13% in this population. CONCLUSION: The coinfection rate was unexpectedly low in this blood donor population where monoinfection with HIV or HBV prevalence was high.


Assuntos
Antígenos HIV/sangue , Infecções por HIV/epidemiologia , Antígenos de Superfície da Hepatite B/sangue , Hepatite B/epidemiologia , Adolescente , Adulto , Distribuição por Idade , Doadores de Sangue , Estudos Transversais , Ensaio de Imunoadsorção Enzimática , Feminino , Infecções por HIV/sangue , Infecções por HIV/complicações , Hepatite B/sangue , Hepatite B/complicações , Humanos , Masculino , Mali/epidemiologia , Pessoa de Meia-Idade , Estudos Soroepidemiológicos , Inquéritos e Questionários , Adulto Jovem
18.
Med Mal Infect ; 34(5): 210-5, 2004 May.
Artigo em Francês | MEDLINE | ID: mdl-16235597

RESUMO

OBJECTIVES: The purpose of this report was to describe epidemiological, clinical, and bacteriological findings in cases of Staphylococcus aureus bacteremia at the Infectious Diseases Clinic in Dakar. MATERIALS AND METHODS: This retrospective study was carried out on data recorded between January 1, 1996 and December 31, 2002. The diagnosis of bacteremia was based on isolation of bacteria from blood culture. Bacterial susceptibility was studied with an antibiogram. Resistance to methicillin was assessed with a disk containing 5 microg of oxacillin on Mueller Hinton Agar containing 5% of NaCl. RESULTS: One hundred and thirty cases of S. aureus bacteremia were recorded. The mean age of patients was 31 years. Nosocomial bacteremia occurred in 22% of the cases. HIV infection was noted in 38 patients (29%). The death rate was 24%. Nosocomial and community-acquired strains were resistant to methicillin, respectively, in 72% and 51% of the cases. Bacteremias due to methicillin-resistant S. aureus strain were nosocomial infections in 23% of the cases. Most of the strains (80-100%) were susceptible to fusidic acid, gentamycin, erythromycin, and pefloxacin. All of them were susceptible to vancomycin. CONCLUSION: Such a high rate of MRSA bacteremia, in particular among nosocomial bacteremia, makes it essential to reinforce preventive measures in our hospitals and to provide them with effective drugs against MRSA, such as vancomycin.


Assuntos
Bacteriemia/epidemiologia , Infecções Estafilocócicas/epidemiologia , Adulto , Idoso , Comorbidade , Infecção Hospitalar/epidemiologia , Farmacorresistência Bacteriana Múltipla , Infecções por Enterobacteriaceae/epidemiologia , Feminino , Infecções por HIV/epidemiologia , Hospitais Universitários/estatística & dados numéricos , Humanos , Pacientes Internados , Masculino , Resistência a Meticilina , Pessoa de Meia-Idade , Prevalência , Estudos Retrospectivos , Senegal/epidemiologia , Staphylococcus aureus/efeitos dos fármacos , Staphylococcus aureus/isolamento & purificação , Infecções Estreptocócicas/epidemiologia , Síndrome de Resposta Inflamatória Sistêmica/epidemiologia , Síndrome de Resposta Inflamatória Sistêmica/microbiologia , Vancomicina/farmacologia , Vancomicina/uso terapêutico
19.
Tese em Francês | AIM (África) | ID: biblio-1277077

RESUMO

Dans ce travail qui concerne la prevalence des varietes histologiques de la M.D.H. et leur incidence pronostic fait sur 50 cas colliges dans le service d'hematologie du C.H.U. de Yopougon; notre etude revele: -La predominance du type 3 histologique avec 52pour cent des cas ; -La M.D.H. est une affection de l'adulte jeune (16-39 ans) majoritairement de sexe masculin (sex-ratio = 2;5) ; -La reponse initiale au traitement n'est pas bonne a 48;8pour cent des cas ; -Les guerisons sont insignifiantes avec 4pour cent des cas et la survie moyenne basse a 12;40 mois. ; -L'existence d'une correlation entre le type histologique et le sexe ; -Le type 4 histologique presente un taux eleve d'echec au traitement avec 75pour cent des cas; 4 cas de deces sur 8 et une survie n'allant pas au-dela de 12 mois confirmant ainsi son caractere de mauvais pronostic


Assuntos
Doença de Hodgkin , Terapêutica
20.
Artigo em Francês | MEDLINE | ID: mdl-8815143

RESUMO

OBJECTIVE: Determine whether certain factors of risk can be identified for post-cesarean section endometritis. METHODS: The hospital charts of patients who underwent cesarean section between April 1, 1992 and March 31, 1993 at Notre-Dame Hospital in Montreal, Canada were evaluated retrospectively. Completed descriptive variables were recorded for all patients. chi 2 analysis and linear regression analysis were used to determine significant values with p < or = 0.05. RESULTS: There were 372 cesarean sections. In this group 52 developed endometritis (14%). These results are similar to those reported in the literature. Seven variables were found to be significant with the chi 2 test: cystitis (p = 0.04), anemia (p = 0.047), cesarean delay (p = 0.049), positive urine culture (p = 0.0000), ruptured membranes > 8 h 30 (p = 0.019), 4 or more vaginal exams (p = 0.034), blood loss > or = 1,000 cm3 (p = 0.026). After linear regression analysis, only three variables remained significant: urine culture (p = 0.000), ruptured membranes > or = 8 h 30 (p = 0.02) and blood loss > or = 1.000 cm3 (p = 0.0005). CONCLUSION: The population at Notre-Dame Hospital is similar to that described in the literature. The incidence of cesarean section and endometritis were also similar with other populations. Physicians should be aware of the importance of urine cultures after withdrawing urine drains since most of the germs found can cause endometritis. It would be important to search for causal germs by direct culture of endometrial material.


Assuntos
Cesárea/efeitos adversos , Endometrite/etiologia , Adolescente , Adulto , Bacteriúria/complicações , Perda Sanguínea Cirúrgica , Feminino , Ruptura Prematura de Membranas Fetais/complicações , Humanos , Incidência , Modelos Lineares , Gravidez , Quebeque , Estudos Retrospectivos , Fatores de Risco
SELEÇÃO DE REFERÊNCIAS
DETALHE DA PESQUISA
...