Decarbonizing the Transport of Microalgae-based Products - The Role of E-mobility.

BACKGROUND: The decarbonization of road transport is a precondition for achieving carbon neutrality. Battery-electric vehicle technology can make this a reality. In this bias, the objective of the article is to shed light on the ongoing debate about the potentially important role of the adoption of electric vehicles in the transport of microalgae- based products to help them advance to a cleaner life cycle. METHODS: Five routes, including unimodal and multimodal conditions, were defined to assess the carbon emissions of the transport system and, more specifically, of road transport. The headquarters of market-leading microalgae manufacturers were selected as the origin of the routes and, as the destination, regions that sustain them. RESULTS: The results reveal the supremacy of road transport of microalgae-based products using electric vehicles powered by nuclear, hydroelectric, and wind, followed by biomass and photovoltaic energy. They also show that the positive impact of wind, water, and photovoltaic energy on the climate, added to the lower battery charging costs and the greater opportunity to generate revenue from the sale of carbon credits, make their tradeoffs. CONCLUSION: The exquisite results of this study convey key messages to decision-makers and stakeholders about the role of electromobility in building a zero-carbon delivery route.

The Role of Light on the Microalgae Biotechnology: Fundamentals, Technological Approaches, and Sustainability Issues.

Light energy directly affects microalgae growth and productivity. Microalgae in natural environments receive light through solar fluxes, and their duration and distribution are highly variable over time. Consequently, microalgae must adjust their photosynthetic processes to avoid photo limitation and photoinhibition and maximize yield. Considering these circumstances, adjusting light capture through artificial lighting in the main culture systems benefits microalgae growth and induces the production of commercially important compounds. In this sense, this review provides a comprehensive study of the role of light in microalgae biotechnology. For this, we present the main fundamentals and reactions of metabolism and metabolic alternatives to regulate photosynthetic conversion in microalgae cells. Light conversions based on natural and artificial systems are compared, mainly demonstrating the impact of solar radiation on natural systems and lighting devices, spectral compositions, periodic modulations, and light fluxes when using artificial lighting systems. The most commonly used photobioreactor design and performance are shown herein, in addition to a more detailed discussion of light-dependent approaches in these photobioreactors. In addition, we present the principal advances in photobioreactor projects, focusing on lighting, through a patent-based analysis to map technological trends. Lastly, sustainability and economic issues in commercializing microalgae products were presented.

Examining the factors associated with functional capacity of community-dwelling older adults using the ICF framework: a cross-sectional study from the Frailty in Brazilian Older Adults Study (FIBRA).

BACKGROUND: There are many factors associated with functioning and disability in older adults and these relationships are not clear. OBJECTIVE: To explore the factors associated with functional capacity of older adults using the framework of the International Classification of Functioning, Disability, and Health (ICF). METHODS: This is a cross-sectional study with a dataset from a survey of 1 377 community-dwelling older adults (≥ 65 years) in a middle-income country. Three functional outcomes were selected to represent the functioning domains: 1) muscle strength for body function; 2) walking speed for activity; and 3) advanced activities of daily living (ADL) for participation. Demographic, clinical, and social information was selected to represent the domains of health conditions and contextual factors (i.e. personal and environmental factors). Multivariate models tested the impact of these factors on each outcome. RESULTS: Depressive symptoms, age, and physical activity were associated with the three outcomes. Muscle strength was also associated with urinary incontinence, visual deficits, female sex, and employment. Walking speed was also associated with urinary incontinence, obesity, fractures due to falls, female sex, health professionals' visits, and walking aid devices. Advanced ADL were also associated with stroke, visual deficits, education, employment, health perception, social support, and walking aid devices. CONCLUSION: Functional capacity of older adults is associated with some non-modifiable factors, such as age and sex. The modifiable factors must be addressed by health professionals and policymakers in the geriatric area, especially depression, obesity, physical inactivity, and social support.

Bioactive Polysaccharides from Microalgae: A Close Look at the Biomedical Applications.

There is a current tendency towards bioactive natural products that can be used in different areas such as food, pharmaceutical, and biomedical. In the last decades, polysaccharides have attracted increasing interest because of their potent nontoxic effects, therapeutic properties, and diversified range of applications. Polysaccharides are complex and heterogeneous macromolecules constituted of different monosaccharides and, in some cases, of glucuronic acid and sulphate groups. Polysaccharides with biological activity can be derived from plants, animals and microorganisms, especially microalgae. Microalgae are considered one of the most promising sources of these compounds that have already proved to have several important biological properties. In this sense, our objective is to elucidate the use of bioactive polysaccharides from microalgae in biomedical applications, emphasizing the biological activity of these compounds. Furthermore, the microalgal biomass production systems and polysaccharides extraction methods were presented and discussed.

Resistance training as a tool for changing muscle mass and frailty status in sarcopenic older women: a quasi-experimental study / Exercícios resistidos modificam a massa muscular e a classificação de fragilidade em idosas sarcopênicas: estudo quase-experimental / Los ejercicios de fuerza provocan cambios en la masa muscular y la clasificación de la fragilidad en ancianas con sarcopenia: un estudio cuasiexperimental

ABSTRACT Frailty and sarcopenia are geriatric syndromes highly prevalent, complex, and hard to diagnose and treat. The literature still lacks a consensus on which resistance training program is better for older people, especially when considering frailty status and sarcopenia. We aimed to evaluate the effectiveness of a progressive resistance training program on muscle mass and frailty status in older sarcopenic women. This study included 18 community-dwelling sarcopenic women aged 65 or older enrolled in the progressive resistance training program. The intervention was based on 75% of each subject's maximum repetition test (3 times/week, for 12 weeks). Before the intervention, 16.7% were frail, and 61.1% were pre-frail; after the intervention, 5.6% were frail, and 50% were pre-frail. The result shows that the intervention reduced frailty status and increased muscle mass (p=0.01). Hence, after the intervention, we observed both a decrease in frailty and a positive change in function, since the percentage of robust women increased twice (p=0.01). We conclude that the progressive resistance training program might be the best strategy to prevent frailty and sarcopenia. Therefore, we suggest using weight resistance training in daily clinical practice to improve muscle mass and decrease frailty status in sarcopenic women.

RESUMO Fragilidade e sarcopenia são consideradas síndromes geriátricas que apresentam grande prevalência e complexidade e são de difícil diagnóstico e tratamento. Ainda não existe consenso quanto ao melhor programa de exercícios resistidos, especialmente quando se considera a fragilidade e a sarcopenia. O objetivo deste estudo foi avaliar a efetividade de um programa de carga na massa muscular e na classificação de fragilidade em idosas sarcopênicas. Participaram 18 idosas sarcopênicas, com idade a partir de 65 anos, que completaram um programa de carga progressiva. A intervenção utilizou o cálculo de 75% de uma repetição máxima (1RM) para cada participante (3 vezes/semana, por 12 semanas). Antes da intervenção, 16,7% foram consideradas frágeis e 61,1% pré-frágeis; após, 5,6% passaram a ser consideradas frágeis e 50% pré-frágeis. Os resultados mostraram que a intervenção alterou a classificação de fragilidade e aumentou a massa muscular das idosas (p=0,01). Observou-se diminuição nos itens de classificação da fragilidade e consequente melhora no perfil funcional, havendo o aumento da porcentagem daquelas consideradas não frágeis após a intervenção (p=0,01). Conclui-se que o programa de exercício resistido progressivo é provavelmente uma das melhores estratégias para prevenir a fragilidade e a sarcopenia. Desta forma, recomenda-se o seu uso na prática clínica diária para melhorar a massa muscular e diminuir o status de fragilidade em mulheres sarcopênicas.

RESUMEN La fragilidad y la sarcopenia son síndromes geriátricos de alta prevalencia y complejidad, además de ser de difícil diagnóstico y tratamiento. Todavía no hay un consenso sobre el programa de ejercicios de fuerza más indicado, especialmente teniendo en cuenta la fragilidad y la sarcopenia. El objetivo de este estudio fue evaluar la efectividad de un programa de carga sobre la masa muscular y la clasificación de la fragilidad en ancianas con sarcopenia. Participaron 18 ancianas con sarcopenia, de más de 65 años y que completaron un programa de carga progresiva. La intervención utilizó el cálculo del 75% de repetición máxima (1RM) para cada participante (3 veces/semana, durante 12 semanas). Antes de la intervención, el 16,7% de las participantes se consideraban frágiles y el 61,1% prefrágiles; después de la intervención, el 5,6% se consideraban frágiles y el 50% prefrágiles. Los resultados mostraron que la intervención produjo cambios en la clasificación de la fragilidad y aumentó la masa muscular de las ancianas (p=0,01). Hubo una reducción en los ítems de clasificación de la fragilidad y una mejora en el perfil funcional, con un aumento del porcentaje de aquellas consideradas no frágiles después de la intervención (p=0,01). Se concluye que el programa de ejercicios de fuerza progresiva se mostró una de las mejores estrategias para prevenir la fragilidad y la sarcopenia. Por tanto, se recomienda aplicarlo en la práctica clínica cotidiana para mejorar la masa muscular y disminuir el estado de fragilidad de mujeres con sarcopenia.

Microalgae-derived polysaccharides: Potential building blocks for biomedical applications.

In recent years, the increasing concern about human health well-being has strongly boosted the search for natural alternatives that can be used in different fields, especially in biomedicine. This has put microalgae-based products in evidence since they contain many bioactive compounds, of which polysaccharides are attractive due to the diverse physicochemical properties and new or improved biological roles they play. Polysaccharides from microalgae, specially exopolysaccharides, are critically important for market purposes because they can be used as anti-inflammatory, immunomodulatory, anti-glycemic, antitumor, antioxidant, anticoagulant, antilipidemic, antiviral, antibacterial, and antifungal agents. Therefore, to obtain higher productivity and competitiveness of these naturally available compounds, the cultivation parameters and the extraction/purification processes must be better optimized in order to bring perspectives for the exploitation of products in commercial and clinical practice. In this sense, the objective of the present review is to elucidate the potential biomedical applications of microalgae-derived polysaccharides. A closer look is taken at the main polysaccharides produced by microalgae, methods of extraction, purification and structural determination, biological activities and their applications, and current status.

Attitudes and beliefs of older adults with acute low back pain: 12-month results from the Brazilian cohort back complaints in the elders.

BACKGROUND: Psychosocial factors have been identified as important predictors of onset, course and persistence of low back pain (LBP) in the general population. OBJECTIVE: To identify factors associated with attitudes/beliefs in older adults with LBP throughout a 12-month follow-up. METHODS: A longitudinal investigation was conducted with 500 participants aged ≥60 years reporting a new (acute) episode of nonspecific LBP. Data were obtained at baseline, 6-week, 3-, 6-, 9-, and 12-month interviews. The study variables were: [dependent] LBP-related attitudes/beliefs that were assessed by the Back Beliefs Questionnaire (BBQ); [independent] age; sex; LBP intensity 'at-the-present-time' of interview and 'over-the-past-week' before interview; LBP frequency; LBP-related treatments; disability; mobility; depressive symptoms; self-perceived recovery; expectation of pain improvement; and expectation for returning to activities. Data were analysed by multiple linear regression analysis. RESULTS: At baseline, 85.7% of the participants were female, had mean age of 69.0 (6.3) years, mean BBQ score of 24.5 (6.5), and 79.6% reported pain complaints after an acute episode of LBP. After 12 months, participants maintained a mean BBQ score of 24.6 (6.6) and 63.3% still reported pain complaints after an acute episode of LBP at baseline. Multivariate analysis showed that disability, advancing age, poor expectation of pain improvement in 3 months, and mobility decline were significantly associated with worse BBQ scores during all follow-ups. CONCLUSION: Ageing, hopelessness, and physical and functional impairment impact pain-related behaviours among older patients seeking healthcare due to acute LBP complaints. Their screening may assist in strategies to manage symptoms and prevent the persistence of pain.

Do Older Brazilian Women Who Participate in a Regular Physical Exercise Program Have Higher Habitual Physical Activity Levels? A Cross-Sectional Study Based on Accelerometer Data.

A cross-sectional study was conducted to compare the habitual physical activity level, measured by accelerometry, gait performance, assessed by the GAITRite® system, handgrip strength, and static balance between older Brazilian women who participate (n = 50; 70.7 ± 5.5 years) and do not participate (n = 50; 70.1 ± 5.6 years) in a regular physical exercise program, and to investigate whether participation in a regular exercise program ensures compliance with physical activity recommendations. Older women who participated in a regular physical exercise program had significantly shorter sedentary activity time (effect size [ES] = 0.54), longer moderate activity time (ES = 0.85), and higher energy expenditure (ES = 0.64), number of steps (ES = 0.82), gait speed (ES = 0.49), and step length (ES = 0.45). However, regular participation in an exercise program did not guarantee compliance with physical activity recommendations. Behavioral changes to increase physical activity levels among older women who do and do not participate in a regular exercise program are necessary.

Cross-cultural adaptation, validity and reproducibility of the Back Beliefs Questionnaire among older Brazilians with acute low back pain. A cross-sectional study.

BACKGROUND: Low back pain (LBP) has emerging as an epidemic, multifactorial and multidimensional condition in older age. Assessment of attitudes and beliefs of patients with back pain is necessary for understanding the impact of psychosocial factors on pain perception and management. OBJECTIVES: To cross-culturally adapt and examine the validity and reproducibility (intra and interrater reliability and agreement) of the Back Beliefs Questionnaire (BBQ) in older Brazilians with acute LBP. DESIGN AND SETTING: Cross-sectional methodological report conducted at the Department of Physical Therapy of the Universidade Federal de Minas Gerais, Belo Horizonte, Brazil. METHODS: The present study was conducted for translating, adapting, and examining the psychometric properties of a questionnaire. Participants aged ≥ 60 years experiencing an acute episode of LBP were recruited. Coefficients of internal consistency, reliability and agreement were obtained using Cronbach's α, intraclass correlations, and standard error of measurement and the smallest detectable change, respectively. RESULTS: Twenty-six participants aged between 60-84 years and reporting a mean of 9.8 (4.3) years of schooling completed the study. The Brazilian Portuguese-language version of the BBQ (BBQ-Brazil) was proposed and presented with adequate conceptual, semantic, operational, and measurement equivalence from the original version. Intra and interrater evaluations showed moderate (0.74) and excellent (0.91) intraclass correlation coefficients, respectively, with small standard error of measurement for both evaluations. Internal consistency was considered adequate (0.70). CONCLUSION: BBQ-Brazil had consistent measurements of validity and reproducibility, and proved to be a valuable tool in clinical practice for addressing attitudes and beliefs of older patients with acute LBP.

Carbon dioxide capture and use in photobioreactors: The role of the carbon dioxide loads in the carbon footprint.

This research evaluated the carbon dioxide capture and use by Scenedesmus obliquus in a photobioreactor under different CO2 loads. Performance indicators, carbon and energy balances, sustainability indicators, and carbon credits on the photobioreactor were assessed. The results expressed that the CO2 loads of 384.9 kg/m3/d (15% CO2) provide the best trade-off for the process. For this condition, maximum biomass productivities of 0.36 kg/m3/d, carbon dioxide conversion rates of 0.44 kgCO2/m3/d, and oxygen release rates of 0.33 kgO2/m3/d were observed, reaching maximum CO2 removal efficiencies of 30.76%. Volatile organic compounds were the major products generated (>80%). However, only <3% was fixed in biomass. From the environmental and economic point of view, the net energy ratio was 3.44, while the potential carbon credit was of 0.04 USD per m3 of culture. Finally, the use of adequate CO2 loads was also proven to be determinant to improve the global performance of the system.

Frailty syndrome in Brazilian older people: a population based study.

This article aims to categorize elderly non-frail (NF), pre-frail (PF) and frail (FF) as to fast and slow gait speed. Compare NF, PF and FF, and analyze associations between fast or slow gait speed with clinical, functional and mental factors. 5,501 elderly (65 years or over; to the Frailty in Brazilian Older People Study), classified as NF, PF and FF (Fried´s frailty phenotype) and, in relation to fast gait speed (≥ 0.8m/s) and slow (< 0.8m/s). Age, sex, body mass index, muscular strength, advanced, instrumental and basic activities of daily living, falls, fear of falling and depressive symptoms were evaluated. Logistic regression analysis investigated associations between variables. The proportion of the slow elderly increased with fragility (NF = 12.39%, PF = 37.56%, FF = 88.83%, p < 0.01). Be woman, performance in activities of daily living, muscle strength and fall were associated with fragility syndrome. The association between frailty and adverse health outcomes reinforces its primacy as an indicator of the functional health of the elderly. Functional capacity, muscular strength, and falls should be evaluated considering their potential for reversibility.

Relationship Between Physical Activity, Depressive Symptoms and Low Back Pain Related Disability in Older Adults With Low Back Pain: A Cross-Sectional Mediation Analysis.

Low back pain (LBP) can be less disabling in those who are physically active. This study analyzed the association between physical activity (PA)- and LBP-related disability in older people with LBP, exploring if this association was mediated by depressive symptoms. The authors analyzed the relationship between PA levels and disability using the short version of the International Physical Activity Questionnaire and the Roland-Morris Disability Questionnaire, respectively, collected at baseline from the Brazilian Back Complaints in the Elders study. The authors investigated depressive symptoms as a mediator of this association using the Center of Epidemiologic Studies Depression scale. PA was inversely associated with disability. This association was smaller when considering the indirect effect through depressive symptoms. Thus, depressive symptoms partially mediated the association between PA and disability in older adults with LBP, and higher levels of PA were associated with less depressive symptoms and disability.

Informações transmitidas às famílias das crianças na emergência na perspectiva da Enfermagem / Nursing professionals' performance regarding the transmission of information to the relatives of children admitted to emergency care units / Información transmitida a las familias de los niños en la emergencia desde la perspectiva de la Enfermería

Objetivo: Analisar a atuação da enfermagem na transmissão das informações às famílias das crianças na emergência. Métodos: Pesquisa qualitativa. Os participantes foram 16 membros da equipe de enfermagem do setor de emergência de um hospital pediátrico público do Rio de Janeiro. O procedimento para a coleta dados foi à entrevista não diretiva em grupo, e os depoimentos foram submetidos à analise temática, à luz da Política Nacional de Humanização. Resultados: As informações transmitidas ao familiar/acompanhante foram relacionadas ao ambiente, normas e rotinas hospitalares, higiene corporal, procedimentos invasivos, e medicamentos. Três momentos distintos para a transmissão de informações foram identificados: admissão da criança, permanência na unidade e alta. Conclusão: A equipe de enfermagem reconhece o direito à informação das famílias das crianças e atua em todos os momentos da assistência à criança no setor de emergência. Acredita-se que a capacitação dos enfermeiros é fundamental para promover transformações na atuação da enfermagem

Objective: This paper analyzes the nursing professionals' performance regarding the transmission of information to the relatives of children admitted to emergency care units. Methods: This qualitative research was performed with 16 members of a nursing team working in an emergency unit of a public pediatric hospital in Rio de Janeiro city, Rio de Janeiro State, Brazil. Data collection was accomplished by using non-directive group interviews, and the statements were submitted to thematic analysis in the light of the Brazilian National Humanization Policy. Results: The information transmitted to the family member/companion was related to the environment, norms and routines, body hygiene, invasive procedures, and medications. Three distinct moments related to the transmission of information were identified: child's admission, stay and discharge within the unit. Conclusion: The nursing team recognized that the children's relatives have the right to information and provided continuous emergency care in the emergency unit. Training nursing professionals is fundamental to improve their performance

Objetivo: Analizar la actuación de la enfermería en la transmisión de informaciones a las familias de niños en la emergencia. Método: Investigación cualitativa. Participaron 16 miembros del equipo de enfermería del sector de emergencia de un hospital pediátrico público en Rio de Janeiro. Datos recolectados por entrevista no directiva en grupo; testimonios sometidos al análisis temático, a la luz de la Política Nacional de Humanización. Resultados: Las informaciones transmitidas a la familia/acompañante se relacionaron con el ambiente, normas y rutinas hospitalarias, higiene corporal, procedimientos invasivos y medicamentos. Emergieron tres categorías: admisión del niño; permanencia en la unidad y; alta. Conclusión: El equipo de enfermería reconoce el derecho a la información a la familia/acompañante y actúa en los momentos de asistencia al niño en emergencia. Se cree que la capacitación de enfermeros es fundamental para promover transformaciones en la actuación de la enfermería

Frailty syndrome in Brazilian older people: a population based study / Síndrome de fragilidade em idosos brasileiros: um estudo de base populacional

Abstract This article aims to categorize elderly non-frail (NF), pre-frail (PF) and frail (FF) as to fast and slow gait speed. Compare NF, PF and FF, and analyze associations between fast or slow gait speed with clinical, functional and mental factors. 5,501 elderly (65 years or over; to the Frailty in Brazilian Older People Study), classified as NF, PF and FF (Fried´s frailty phenotype) and, in relation to fast gait speed (≥ 0.8m/s) and slow (< 0.8m/s). Age, sex, body mass index, muscular strength, advanced, instrumental and basic activities of daily living, falls, fear of falling and depressive symptoms were evaluated. Logistic regression analysis investigated associations between variables. The proportion of the slow elderly increased with fragility (NF = 12.39%, PF = 37.56%, FF = 88.83%, p < 0.01). Be woman, performance in activities of daily living, muscle strength and fall were associated with fragility syndrome. The association between frailty and adverse health outcomes reinforces its primacy as an indicator of the functional health of the elderly. Functional capacity, muscular strength, and falls should be evaluated considering their potential for reversibility.

Resumo O artigo tem por objetivos categorizar idosos não frágeis (NF), pré-frágeis (PF) e frágeis (FF) quanto à velocidade rápida e lenta de marcha. Compara NF, PF e FF, e analisa associações entre velocidade de marcha rápida e lenta com fatores clínicos, funcionais e mentais. 5.501 idosos (65 anos ou mais; Estudo de Fragilidade em Idosos Brasileiros - Rede Fibra), classificados em NF, PF e FF (fenótipo de fragilidade de Fried) e, quanto a velocidade de marcha rápida (≥ 0.8m/s) e lenta (< 0.8m/s). Avaliou-se idade, sexo, índice de massa corpórea, força muscular, atividades instrumentais, básicas e avançadas de vida diária, quedas, medo de quedas e sintomas depressivos. Análise de regressão logística para verificar associação entre variáveis. A proporção de idosos lentos aumentou com a fragilidade (NF = 12,39%, PF = 37,56%, FF = 88,83%, p < 0,01). Ser mulher, desempenho nas atividades de vida diária, força muscular e relato de quedas associou-se com a fragilidade. A associação entre fragilidade e eventos adversos de saúde reforçou sua importância em ser um indicador da saúde funcional dos idosos. Capacidade funcional, força muscular e ocorrência de quedas devem ser avaliados, considerando seu potencial de reversibilidade.

Declínio da velocidade da marcha e desfechos de saúde em idosos: dados da Rede Fibra / Disminución de la velocidad de la marcha y resultados en la salud de los ancianos: datos de la Red Fibra / Decreased gait speed and health outcomes in older adults: Rede FIBRA's data

RESUMO A velocidade da marcha (VM) tem sido considerada um marcador de saúde em idosos capaz de predizer desfechos adversos de saúde, mas a compreensão de fatores associados a ela ainda é limitada e controversa. O objetivo deste trabalho é identificar desfechos adversos de saúde relacionados ao declínio da velocidade de marcha em idosos comunitários. Trata-se de estudo transversal e multicêntrico, que avaliou o autorrelato de doenças crônicas e de hospitalização no último ano, polifarmácia e velocidade de marcha. Utilizou-se análise de regressão logística para estimar os efeitos de cada variável independente na chance de os idosos apresentarem declínio na velocidade de marcha inferior (VM<0,8m/s) (α=0,05). Participaram da pesquisa 5.501 idosos. A menor velocidade da marcha mostrou-se associada a portadores de doenças cardíacas (OR=2,06; IC: 1,67-2,54), respiratórias (OR=3,25; IC: 2,02-5,29), reumáticas (OR=2,16; IC: 1,79-2,52) e/ou depressão (OR=2,51; IC: 2,10-3,14), hospitalizados no último ano (OR=1,51; IC: 1,21-1,85) e polifarmácia (OR=2,14; IC: 1,80-2,54). Assim, os resultados indicaram que idosos com velocidade de marcha menor que 0,8m/s apresentam maior risco de eventos adversos de saúde. Dessa forma, sugere-se que a velocidade de marcha não seja negligenciada na avaliação de idosos comunitários, inclusive na atenção básica.

RESUMEN La velocidad de la marcha (VM) se ha considerado un marcador de salud en los ancianos capaz de predecir resultados adversos en la salud, pero la comprensión de sus factores asociados todavía es limitada y controvertida. El presente estudio tiene como objetivo identificar los resultados adversos para la salud relacionados con la disminución de la velocidad de la marcha en los ancianos comunitarios. Se trata de un estudio transversal y multicéntrico, el que evaluó el autoinforme de enfermedades crónicas y de la hospitalización en el último año, la polifarmacia y la velocidad de la marcha. Se utilizó el análisis de regresión logística para estimar los efectos de cada variable independiente sobre la posibilidad de que los ancianos presenten una disminución más baja en la velocidad de la marcha (VM<0,8 m/s) (α=0,05). Participaron en el estudio 5.501 ancianos. La velocidad de marcha más baja estuvo asociada a portadores de enfermedades cardíacas (OR=2,06; IC: 1,67-2,54), respiratorias (OR=3,25; IC: 2,02-5,29), reumáticas (OR=2,16; IC: 1,79-2,52) y/o depresión (OR=2,51; IC: 2,10-3,14), hospitalizados en el último año (OR=1,51; IC: 1,21-1,85) y polifarmacia (OR=2,14; IC: 1,80-2,54). De esta manera, los resultados indicaron que los ancianos con velocidades de marcha por debajo de 0,8m/s presentan un mayor riesgo de eventos adversos para la salud. Por lo tanto, se sugiere que la velocidad de la marcha no debe ser descuidada en la evaluación de ancianos comunitarios, incluso en la atención primaria.

Abstract Gait speed (GS) can predict adverse health outcomes. However, an understanding of its associated factors is still limited and with some controversy. The objective of this study was to identify adverse health outcomes related to the decline in gait speed in community-dwelling older adults. This is a cross-sectional study that evaluated records of chronic diseases and hospitalization in the last year, polypharmacy, and gait speed. Logistic regression analysis was used to estimate the effects of each independent variable on the chance of older adults presenting a decline in gait speed (GS<0.8 m/s) (α=5%). In total, 5,501 older adults participated. Brazilian older adults with heart diseases (OR=2.06; 1.67-2.54 CI), respiratory diseases (OR=3.25; 2.02-5.29 CI), rheumatic (OR=2.16; 1.79-2.52 CI) and/ or depression diseases (OR=2.51; 2.10-3.14 CI); hospitalized in the last year (OR=1.51; 1.21-1.85 CI) and under polypharmacy (OR=2.14; 1.80-2.54 CI) were associated with lower gait speed. Thus, the results showed that those with gait speed lower than 0.8 m/s are at higher risk of some adverse health events. Therefore, it is suggested that gait speed should not be neglected in the evaluation in community-dwelling older adults, including basic health care.

Prediction equation for the mini-mental state examination: influence of education, age, and sex / Equação de predição para o miniexame do estado mental: influência da educação, idade e sexo / Ecuación de predicción para el mini-examen del estado mental: influencia de la educación, edad y sexo

ABSTRACT The mini-mental state examination (MMSE) is a screening test used worldwide for identifying changes in the scope of cognition. Studies have shown the influence of education, age and sex in the MMSE score. However, in Brazil, the studies consider only one factor to score it. The aim of this study was to establish a prediction equation for the MMSE. An exploratory cross-sectional study was developed and trained researchers examined participants at the community. The volunteers were evaluated by the MMSE and also by the Geriatric Depression Scale (GDS). The MMSE score was the dependent variable. Age, educational level, sex, and GDS score were the independent variables. Multivariate regression analysis was used to determine the model of best prediction value for MMSE scores. A total of 250 participants aged 20-99 years, without cognitive impairment, were assessed. The educational level, age, and sex explained 38% of the total variance of the MMSE score (p<0.0001) and resulted in the following equation: MMSE=23.350+0.265(years of schooling)-0.042(age)+1.323(sex), in which female=1 and male=2. The MMSE scores can be better explained and predicted when educational level, age, and sex are considered. These results enhance the knowledge regarding the variables that influence the MMSE score, as well as provide a way to consider all of them in the test score, providing a better screening of these patients.

RESUMO O mini-exame do estado mental (MEEM) é um teste de rastreio mundialmente utilizado para identificar alterações no âmbito da cognição. Estudos têm demonstrado a influência da educação, idade e gênero na pontuação do MEEM. No entanto, no Brasil, os estudos consideram apenas um fator para a pontuação no teste. O objetivo do estudo foi estabelecer uma equação preditiva para o MEEM. Um estudo transversal exploratório foi desenvolvido e examinadores treinados avaliaram participantes da comunidade. Os voluntários foram avaliados pelo MEEM e pela Escala de Depressão Geriátrica (EDG). A pontuação do MEEM foi a variável dependente. A idade, nível educacional, gênero e pontuação na EDG foram as variáveis independentes. A análise de regressão multivariada foi utilizada para determinar o modelo de melhor valor preditivo para os escores do MEEM. Foram avaliados 250 indivíduos entre 20 e 99 anos, sem comprometimento cognitivo. O nível educacional, a idade e o sexo explicaram 38% da variância total da pontuação do MEEM (p<0,0001) e resultaram na equação: MEEM=23,350+0,265(anos de escolaridade)-0,042(idade)+1,323(gênero), em que mulher=1 e homem=2. A pontuação do MEEM pode ser melhor explicada e predita quando o nível educacional, idade e gênero são considerados. Os resultados contribuem para o conhecimento sobre as variáveis que influenciam o escore do MEEM, bem como fornece uma maneira de considerá-las na pontuação do teste, proporcionando uma melhor triagem desses pacientes.

RESUMEN El mini-examen del estado mental (MEEM) es una prueba de rastreo mundialmente utilizada para identificar alteraciones en el ámbito de la cognición. Los estudios han demostrado la influencia de la educación, la edad y el sexo en la puntuación del MEEM. Sin embargo, en Brasil, los estudios consideran sólo un factor para la puntuación en la prueba. El objetivo del estudio fue establecer una ecuación predictiva para el MEEM. Un estudio transversal exploratorio fue desarrollado y examinadores entrenados evaluaron a participantes de la comunidad. Los participantes fueron evaluados por el MEEM y la Escala de Depresión Geriátrica (EDG). La puntuación del MEEM fue la variable dependiente. La edad, nivel educativo, sexo y puntuación en la EDG fueron las variables independientes. El análisis de regresión multivariada fue utilizado para determinar el modelo de mejor valor predictivo para los escores del MEEM. Se evaluaron 250 individuos entre 20 y 99 años, sin comprometimiento cognitivo. El nivel educativo, la edad y el sexo explicaron el 38% de la varianza total de la puntuación del MEEM (p <0,0001) y resultaron en la ecuación: MEEM=23,350+0,265(años de escolaridad)-0,042 (edad)+1,323 (sexo), en que mujer = 1 y hombre = 2. La puntuación del MEEM puede ser mejor explicada y predecible cuando se considera el nivel educativo, la edad y el sexo. Los resultados contribuyen para el conocimiento sobre las variables que influencian el score del MEEM, así como proporciona una manera de considerar las variables en la puntuación de la prueba, proporcionando una mejor forma de triar a estos pacientes.

Energy Expenditure in Older Adults Who Are Frail: A Doubly Labeled Water Study.

BACKGROUND AND PURPOSE: Frailty is a common and important geriatric syndrome, distinct from any single chronic disease, and an independent predictor of mortality. It is characterized by age-associated decline in physiological reserve and function across multiple systems, culminating in a vicious cycle of altered energy expenditure. The total energy expenditure (TEE) of an individual includes the resting metabolic rate (RMR), the thermic effect of feeding, and the energy expenditure in physical activity (PAEE). The investigation of the energy expenditure of older adults who are frail is essential for better understanding the syndrome. Therefore, we compared the RMR, the PAEE, the physical activity level (PAL), and the TEE of older adults who were frail with those who were not frail. METHODS: A cross-sectional study was conducted with 26 community-dwelling older adults (66-86 years of age). Older adults in the frail and nonfrail groups were matched for age and gender, and the matched pairs were randomly selected to continue the study. The RMR was measured by indirect calorimetry. The TEE was obtained by the multipoint, doubly labeled water method. After collecting a baseline urine sample, each participant received an oral dose of doubly labeled water composed of deuterium oxide and oxygen-18 (H2O). Subsequently, urine samples were collected on the 1st, 2nd, 3rd, 7th, 12th, 13th, and 14th days after the baseline collection and analyzed by mass spectrometry. RESULTS AND DISCUSSION: The older adults who were frail presented significantly lower PAEE (1453.7 [1561.9] vs 3336.1 [1829.3] kj/d, P < .01), PAL (1.4 [0.3] vs 1.9 [0.6], P = .04), and TEE (7919.0 [2151.9] vs 10442.4 [2148.0] kj/d, P < .01) than the older adults who were nonfrail. There was no difference in their RMRs (5673.3 [1569.2] vs 6062.0 [1891.7] kj/d, P = .57). Frailty has been associated with a smaller lean body mass and with a disease-related hypermetabolic state, which might explain the lack of difference in the RMR. The PAL of the older adults who were frail was below the recommended level for older adults and determined a lower PAEE and TEE when compared with older adults who were not frail. CONCLUSION: This study showed that low energy expenditure in physical activity is a main component of frailty. The PAL of the older adults who were frail was far below the recommended level for older adults.

A presença do familiar/acompanhante da criança submetida à cirurgia ortopédica: implicações para a enfermagem / The presence of the family/child accompanied by orthopedic surgery: implications for nursing

Introdução: Quando a criança é submetida à cirurgia, a presença do familiar transmite segurança e tranquilidade nos momentos que perpassam o período perioperatório. Objetivos: Descrever as experiências do familiar/acompanhante da criança submetida à cirurgia ortopédica no período perioperatório; analisar a presença do familiar/acompanhante da criança submetida à cirurgia no período perioperatório; e discutir a presença do familiar/acompanhante no período perioperatório e suas implicações para a prática assistencial de enfermagem. Método: estudo qualitativo baseado nos conceitos de família saudável e de presença como elemento constitutivo do cuidado familial. O cenário foi uma unidade de pediatria de um hospital especializado em ortopedia no município do Rio de Janeiro. Os participantes foram nove familiares/acompanhantes das crianças internadas e que foram submetidas à cirurgia. Os procedimentos metodológicos foram um formulário de caracterização dos acompanhantes e das crianças e a entrevista não-diretiva em grupo. Os dados foram analisados por meio da análise temática. O projeto foi aprovado no Comitê de Ética em Pesquisa da Escola de Enfermagem Anna Nery e Instituto de Atenção à Saúde São Francisco de Assis e no Comitê de Ética em Pesquisa da instituição coparticipante. Resultados: No pré-operatório, as reações dos familiares/acompanhantes, das crianças e da equipe foram bastante diversificadas, tendo em vista as informações da criança e seu acompanhante e também dos conhecimentos técnico-científicos da equipe. Na sala de cirurgia, os depoimentos apontaram a segurança da criança diante da presença do familiar/acompanhante. No pós-operatório, as depoentes destacaram o êxito da cirurgia e a expectativa de vida das crianças. A religiosidade e a distância da família permeiam as experiências do familiar/acompanhante durante o período perioperatório. Conclusões: A presença do familiar/acompanhante no perioperatório resulta na ampliação da interação família- criança-equipe, estabelecendo situações propícias ao cuidado centrado na criança e sua família em situações cirúrgicas, reafirmando a relevância da presença da família e a garantia do direito da criança de ter um acompanhante.

Introduction: When the child undergoes surgery, the presence of the relative conveys safety and tranquility during the perioperative period. Objectives: describe the experiences of the family member / companion of the child submitted to orthopedic surgery in the perioperative period; presence of the family member / companion of the child submitted to surgery in the perioperative period, to discuss the presence of the family member / companion in the perioperative period and its implications for nursing care practice. Method: qualitative study based on the concepts of healthy family and presence as a constituent element of family care. The setting was a pediatric unit of a hospital specialized in orthopedics in the city of Rio de Janeiro. Participants were nine relatives / companions of hospitalized children who underwent surgery. The methodological procedures were a form of characterization of the companions and the children, non-directive interview in the group. The data were analyzed by means of the thematic analysis. The project was approved by the Research Ethics Committee of the Anna Nery School of Nursing and the São Francisco de Assis Health Care Institute and the Research Ethics Committee of the co-participating institution. Results: In the preoperative period, the reactions of the family / companions, the child and the team were quite diversified considering the information of the child and his / her companion, as well as the technical-scientific knowledge of the team. In the operating room, the testimonies pointed to the child's safety in the presence of the relative / companion. In the postoperative period, the deponents highlighted the success of the surgery and the children's life expectancy. The religiosity and the experiences of the family membercompanion during the perioperative period. The presence of the family membercompanion in the perioperative results in the expansion of the family-child-team interaction, establishing situations propitious to care centered on the child and his family in surgical situations, reaffirming the relevance of family presence and the guarantee the right of the child to have an accompanying person.

Prevalência e transição para a fragilidade em idosos com alteração cognitiva em uma coorte de um ano / Prevalence and transition to frailty in older adults with cognitive impairment: a 1-year cohort study

Alteração cognitiva e fragilidade são frequentemente encontradas em idosos e parece haver uma relação entre elas. Entretanto, pouco se sabe sobre a prevalência e a transição para a fragilidade nos idosos com alteração cognitiva, principalmente para a população brasileira. O objetivo do estudo foi avaliar a prevalência e a transição entre os estados de fragilidade em um grupo de idosos com alteração cognitiva em uma coorte prospectiva de um ano. Neste estudo de coorte foram avaliados 59 idosos comunitários com alteração cognitiva (≥ 65 anos). O indivíduo frágil foi identificado por apresentar pelo menos três dos seguintes critérios: perda de peso não intencional, fraqueza da força de preensão palmar, exaustão, lentidão na marcha e baixo nível de atividade física. Quando o indivíduo apresentou um ou dois critérios, foi considerado pré-frágil; quando não apresentou nenhum critério, foi considerado não frágil. A função cognitiva foi avaliada pelo Mini Exame do Estado Mental e a gravidade, pela Clinical Dementia Rating Scale. Do total de 59 idosos avaliados na linha de base, 28 (47,5%) eram frágeis, a mesma quantidade era de pré-frágeis e apenas 3 idosos eram não frágeis. Em 12 meses, verificou-se uma transição para fragilidade de 33,3%. Este estudo mostrou que a prevalência de fragilidade é alta entre os idosos com alteração cognitiva e, em um período de 12 meses, novos casos de fragilidade ocorreram entre os idosos com alteração cognitiva. Entretanto, mais estudos são necessários para investigar com melhor precisão uma relação existente entre o declínio cognitivo e a fragilidade

Cognitive impairment and frailty are often found in older people, and they appear to be related to each other. However, little is known about the prevalence and transition to frailty in older adults with cognitive impairment, especially in the Brazilian population. The present study aimed to determine the prevalence and transitions between frailty states in a cohort of older adults with cognitive impairment followed prospectively for 1 year. A cohort of 59 community-dwelling older adults (aged ≥ 65 years) with cognitive impairment was evaluated. Individuals were classified as frail by the presence of 3 or more of the following criteria: unintentional weight loss; reduced grip strength; exhaustion; slowness; and low physical activity level. Individuals meeting 1 or 2 criteria were classified as prefrail, and those meeting 0 criteria as nonfrail. Cognitive function was assessed by the Mini-Mental State Examination, and severity, by the Clinical Dementia Rating scale. Of 59 older adults evaluated at baseline, 28 (47.5%) were classified as frail, 28 (47.5%) as prefrail, and only 3 (5%) as nonfrail. Over 12 months, 33.3% of participants transitioned from prefrail to frail. The present study showed a high prevalence of frailty in older adults with cognitive impairment and, within 12 months, new cases of frailty were identified in this population. Therefore, more research is needed to further investigate the relationship between cognitive decline and frailty.

The fabric of resilience among the elderly and the reinvention of the self despite the difficulties faced / A tessitura da resiliência em idosos, a reinvenção de si "apesar de"

Abstract Objective :To seek an understanding of how frail elderly persons construct resilience. Method: The "signs, meanings and actions" model was used. The population was randomly selected among elderly persons classified as robust or pre-frail in the FIBRA-study, Belo Horizonte, Minas Gerais, Brazil. Thirteen elderly persons (aged 69 to 86) were interviewed. Results: a) the construction of bonds - a healthy relationship with spouses, sons, daughters, grandchildren and great-grandchildren brings meaning to and sustains life and contributes to its organization; b) the reinvention of oneself - when suffering trauma, elderly people seek paths that can give sense to life, even if difficult memories persist; c) religiosity: catholic, evangelical or spiritualist experiences strengthen; cures, protections and so-called miracles are valued, and the religious community represents a space for belonging. Conclusion: Resilience is constructed through the bonds between the elderly person and those close to them, and in the search for solutions, including through the religious experience.

Resumo Objetivo: Buscar uma compreensão, a partir da visão de idosos em processo de fragilização, sobre como tecem sua resiliência. Método: Foram entrevistados 13 idosos (69 a 86 anos), selecionados aleatoriamente entre idosos classificados como robustos ou pré-frágeis em Belo Horizonte, Minas Gerais, Brasil, na Rede FIBRA. A coleta e a análise dos dados foram fundamentadas no modelo de "Signos, significados e ações". Resultados: a) Construção de vínculos - a relação saudável com os cônjuges, filhos, netos e bisnetos traz sentido à vida, sustenta e se torna um organizador; b) reinvenção de si mesmo - ao sofrer um trauma, uma parte da pessoa busca caminhos que possam dar sentido à vida, mesmo se persistem as memórias sofridas; c) a religiosidade - católica, evangélica ou espírita - fortalece para trabalhar na solução de problemas e aceitar o imutável: valorizam-se curas, proteções, milagres e a comunidade religiosa como espaço de pertença. Conclusão: Os idosos constroem resiliência na sua ligação com as pessoas próximas, na busca de soluções, e na experiência religiosa.