[Preliminary results of the Russia (St.Petersburg)/WHO program for the evaluation of the effectiveness of breast self-examination]. / Promezhutochnye rezul'taty programmy Rocciia (Sankt-Peterburg)/VOZ po otsenke éffektivnosti samoobsledovaniia molochnykh zhelez.

Although an absolute difference of 10% (65,4 vs. 54,9%) in 5- and 9-year survival in breast cancer patients was recorded between the self-examination and control groups a large-scale randomized population-controlled study of 122,471 females has failed to provide significant differences (Log-rank - 0,774, p > 0.05). No significant decrease in mortality was observed in the self-examination group as compared with the untrained controls. As a result of providing more information to the population on risk factors. twice as many of the trained females consulted oncologists. Also, the number of early detection of breast tumor (T1-2NOMO) in both groups was 1,5-2,5 times that recorded elsewhere. Since 3,55 per 1,000 patients with breast tumors per year, aged 50-59, died of cardio-vascular disease, i.e. 3,1 times the expected 1,16 per 1,000, more attention should be focused on timely diagnosis and treatment of concomitant cardio-vascular pathology.

[A method for making up the cost pricing of clinico-diagnostic studies in oncology]. / Metodika formirovaniia sebestoimosti klniko-diagnosticheskikh issledovanii v onkologii.

The functioning of the present-day system of public health is largely determined by the extent and effectiveness of the use of resources. The saving of resources is reflected in the costs. The research was concerned with development of methods of calculating the costs of clinical laboratory tests. Due account of costs offers means for evolving new patterns of self-reliance accounting and paid medical services.

[Methodology of calculating the net cost of biochemical clinical studies]. / Metodologiia rascheta sebestoimosti biokhimicheskikh klinicheskikh issledovanii.

A method for estimating the net cost of biochemical investigations has been developed as exemplified by the clinical laboratory of the N. N. Petrov Research Institute of Oncology of the USSR Ministry of Health. A data bank including information on the wages fund, cost of material used, equipment wear, and other expenditures was created for these estimations. Labor consumption for each of the 27 types of biochemical investigations comprised the production time of physicians (79.3 percent) and laboratory assistants (87.3 percent). Net cost of physicians' productive minute has made up 0.04 roubles, that of laboratory assistants' minute, 0.02 roubles. Wastes unrelated to the time of investigation were also taken into consideration.

[Economic bases of treatment intensification at specialized oncological facilities]. / Ekonomicheskoe obosnovanie intensifikatsii lecheniia v spetsializirovannom onkologicheskom uchrezhdenii.

The purpose of the study was to work out economic rationale for intensifying treatment at specialized oncological establishments. Modern modalities of cancer treatment require patients to be admitted to specialized hospitals. However, at present nearly half of them receive treatment in general medical establishments which, as a rule, do not have facilities for combined and complex treatment. It is estimated that shifting patient examination emphasis from hospital to outpatient clinic might increase the clinical bed turnover by 6.7% which, in turn, will allow to treat 43000 patients more in specialized hospitals every year. The introduction of such scheme will cost 6.8 times less than commission of new beds required for management of the equivalent number of cancer patients.