RESUMO
Background: Pollen-food syndrome (PFS) is an allergic reaction to fresh fruits, vegetables and/or nuts that can occur in patients who are allergic to pollen. The prevalence of PFS in children is not clearly known. Objective: The objective of this study was to determine the frequency and clinical features of PFS in pediatric patients with pollen-induced allergic rhinitis (AR). Method: This study was conducted in the pediatric allergy outpatient clinic of our hospital. Pollen-induced seasonal AR patients who were evaluated for any symptoms appearing after consuming any fresh fruits and vegetables. Results: Six hundred and seventy-two pollen-sensitized patients were included in this study. The symptoms related to PFS were reported in 22 (3.3%) patients. The median age of the patients was 12.3 years and 59% (n = 13) were female. Peach was the most common culprit (22%). There were isolated oropharyngeal symptoms in 20 (91%) patients and anaphylaxis in two (9%) patients with the suspected food. The multiple logistic regression analysis revealed that female gender, history of atopic dermatitis and allergic diseases in the family were the potential risk factors for PFS [Odds ratio 95% CI: 3.367 (1.344-8.435), 5.120 (1.935-13.550), 3.046 (1.239-7.492), respectively]. Conclusion: PFS can be seen in children who are followed up for pollen-induced AR. The symptoms of PFS are usually mild and transient. However, comprehensive evaluation of patients is important since serious systemic reactions such as anaphylaxis can also be observed
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Assuntos
Humanos , Feminino , Criança , Rinite Alérgica Sazonal/epidemiologia , Hipersensibilidade Alimentar/epidemiologia , Rinite Alérgica Sazonal/diagnóstico , Plantas/efeitos adversos , Frutas/efeitos adversos , Modelos Logísticos , Imunoterapia , Anafilaxia/epidemiologiaRESUMO
BACKGROUND: Pollen-food syndrome (PFS) is an allergic reaction to fresh fruits, vegetables and/or nuts that can occur in patients who are allergic to pollen. The prevalence of PFS in children is not clearly known. OBJECTIVE: The objective of this study was to determine the frequency and clinical features of PFS in pediatric patients with pollen-induced allergic rhinitis (AR). METHOD: This study was conducted in the pediatric allergy outpatient clinic of our hospital. Pollen-induced seasonal AR patients who were evaluated for any symptoms appearing after consuming any fresh fruits and vegetables. RESULTS: Six hundred and seventy-two pollen-sensitized patients were included in this study. The symptoms related to PFS were reported in 22 (3.3%) patients. The median age of the patients was 12.3 years and 59% (n=13) were female. Peach was the most common culprit (22%). There were isolated oropharyngeal symptoms in 20 (91%) patients and anaphylaxis in two (9%) patients with the suspected food. The multiple logistic regression analysis revealed that female gender, history of atopic dermatitis and allergic diseases in the family were the potential risk factors for PFS [Odds ratio 95%CI: 3.367 (1.344-8.435), 5.120 (1.935-13.550), 3.046 (1.239-7.492), respectively]. CONCLUSION: PFS can be seen in children who are followed up for pollen-induced AR. The symptoms of PFS are usually mild and transient. However, comprehensive evaluation of patients is important since serious systemic reactions such as anaphylaxis can also be observed.
Assuntos
Hipersensibilidade Alimentar/epidemiologia , Rinite Alérgica Sazonal/epidemiologia , Adolescente , Alérgenos/imunologia , Criança , Feminino , Hipersensibilidade Alimentar/diagnóstico , Hipersensibilidade Alimentar/patologia , Frutas/imunologia , Humanos , Incidência , Masculino , Pólen/imunologia , Prevalência , Rinite Alérgica Sazonal/diagnóstico , Rinite Alérgica Sazonal/patologia , Fatores de Risco , Verduras/imunologiaRESUMO
BACKGROUND: Atopic dermatitis (AD) is the most common chronic skin disease in childhood. There is no definitive test for diagnosing AD. The Hanifin-Rajka criteria (HRC) and The United Kingdom Working Party criteria (UKC) are the most used in the literature. It is aimed to evaluate the clinical efficacy of HRC and UKC in pediatric age. METHODS: Children diagnosed AD in the pediatric allergy clinic were enrolled. Patients with skin problems other than AD were involved as controls. All participants were evaluated for HRC and UKC at the time of diagnosis. Clinical diagnosis by the pediatric allergist was determined as the gold standard. RESULTS: 200 children with AD and 90 controls were enrolled in the study. Median (interquartile range, IQR) age of AD patients was 13.5 (7-36) months. There was no significant difference in age and sex between groups (p=0.11 and p=0.34, respectively). The HRC were superior to the UKC for sensitivity, negative predictive value, kappa and accuracy rate (94% vs. 72%, 84% vs. 60%, 0.68 vs. 0.56 and 87 vs. 78, respectively). On the other hand, specificity and positive predictive value of UKC were better than those of HRC (92% vs. 71% and 95% vs. 88%, respectively). CONCLUSION: HRC seem to be better in diagnosing AD than UKC for young children. Further studies are needed to evaluate comparableness of HRC and UKC for AD in childhood in order to generate an international consensus for clinical trials.
Assuntos
Dermatite Atópica/diagnóstico , Adolescente , Criança , Pré-Escolar , Feminino , Humanos , Lactente , MasculinoRESUMO
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Humanos , Masculino , Pré-Escolar , Dessensibilização Imunológica/métodos , Etoposídeo/efeitos adversos , Anafilaxia/terapia , Hipersensibilidade a Drogas/imunologia , Antineoplásicos Fitogênicos/efeitos adversos , Mitose , Epinefrina/uso terapêutico , Retinoblastoma/tratamento farmacológicoRESUMO
Background: In recent years, laryngopharyngeal reflux (LPR) in children has been taken into consideration. Objective: The aim of this study was to assess the laryngoscopic findings in children diagnosed LPR and/or gastro-oesophageal reflux (GERD).Methods: The findings of 49 patients with at least one or more respiratory complaint such as chronic cough, wheezing, hoarseness, recurrent laryngitis, and throat clearing/postnasal discharge suggesting LPR were evaluated retrospectively. The diagnosis of LPR + GERD or GERD was done by the clinical history and 24 h double-probe pH monitoring and/or scintigraphy. Results: Thirty eight out of 49 patients examined by laryngoscopy underwent 24 h double-probepH monitoring and/or scintigraphy. Thirty of them were diagnosed as LPR + GERD or GERD by any test positivity. Twelve of 30 patients diagnosed with LPR + GERD or GERD had a positive laryngeal finding on the examination of fibre optic laryngoscopy. The most common finding with eight cases was arytenoid erythema A sensitivity of 40% and specificity of 50% for the laryngoscopy in the diagnosis of LPR/GERD were found. Conclusion: In children with unexplained respiratory symptoms, laryngopharyngeal reflux should be suspected. Therefore, until enough data on this issue in the literature accumulates, the history and the laboratory findings of the patients obtained from various techniques to document paediatric LPR should be evaluated together(AU)
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Humanos , Masculino , Feminino , Criança , Refluxo Laringofaríngeo/diagnóstico , Laringoscopia/métodos , Refluxo Gastroesofágico/diagnóstico , Tecnologia de Fibra Óptica/métodos , Doenças Respiratórias/diagnóstico , Asma/diagnóstico , Tosse/etiologia , Diagnóstico DiferencialRESUMO
BACKGROUND: In recent years, laryngopharyngeal reflux (LPR) in children has been taken into consideration. OBJECTIVE: The aim of this study was to assess the laryngoscopic findings in children diagnosed LPR and/or gastro-oesophageal reflux (GERD). METHODS: The findings of 49 patients with at least one or more respiratory complaint such as chronic cough, wheezing, hoarseness, recurrent laryngitis, and throat clearing/postnasal discharge suggesting LPR were evaluated retrospectively. The diagnosis of LPR+GERD or GERD was done by the clinical history and 24 h double-probe pH monitoring and/or scintigraphy. RESULTS: Thirty eight out of 49 patients examined by laryngoscopy underwent 24 h double-probe pH monitoring and/or scintigraphy. Thirty of them were diagnosed as LPR+GERD or GERD by any test positivity. Twelve of 30 patients diagnosed with LPR+GERD or GERD had a positive laryngeal finding on the examination of fibre optic laryngoscopy. The most common finding with eight cases was arytenoid erythema A sensitivity of 40% and specificity of 50% for the laryngoscopy in the diagnosis of LPR/GERD were found. CONCLUSION: In children with unexplained respiratory symptoms, laryngopharyngeal reflux should be suspected. Therefore, until enough data on this issue in the literature accumulates, the history and the laboratory findings of the patients obtained from various techniques to document paediatric LPR should be evaluated together.
Assuntos
Refluxo Gastroesofágico/diagnóstico , Refluxo Laringofaríngeo/diagnóstico , Transtornos Respiratórios/diagnóstico , Adolescente , Criança , Pré-Escolar , Diagnóstico Diferencial , Feminino , Refluxo Gastroesofágico/complicações , Refluxo Gastroesofágico/fisiopatologia , Humanos , Lactente , Refluxo Laringofaríngeo/complicações , Refluxo Laringofaríngeo/fisiopatologia , Laringoscopia , Masculino , Prognóstico , Transtornos Respiratórios/complicações , Transtornos Respiratórios/fisiopatologia , Estudos Retrospectivos , Sensibilidade e EspecificidadeAssuntos
Humanos , Masculino , Pré-Escolar , Hipersensibilidade Alimentar/complicações , Hipersensibilidade Alimentar/diagnóstico , Hipersensibilidade Alimentar/epidemiologia , Cicer/efeitos adversos , Cicer/imunologia , Hipersensibilidade a Ovo/complicações , Hipersensibilidade a Ovo/diagnóstico , Hipersensibilidade a Ovo/epidemiologia , Lens (Planta)/efeitos adversos , Lens (Planta)/imunologia , Fabaceae/efeitos adversos , Fabaceae/imunologiaAssuntos
Humanos , Masculino , Criança , Imunoglobulina E/sangue , Imunoglobulina E , Imunoglobulina E/imunologia , Alérgenos/efeitos adversos , Alérgenos/imunologia , Baratas/imunologia , Eosinofilia/sangue , Eosinofilia/imunologia , Eosinofilia/etiologia , Testes Cutâneos , Eosinófilos/imunologia , Baratas/patogenicidadeRESUMO
BACKGROUND: The pathogenesis of asthma is associated with both genetic and environmental factors. Allergen sensitization is an important risk factor in asthma development. AIM: To evaluate sensitivity to allergens by using the skin prick test in patients with a diagnosis of bronchial asthma. METHOD: Patients with a diagnosis of bronchial asthma followed-up at the Ministry of Health, Diskapi Children's Diseases Training and Research Hospital in Ankara (Turkey) between January 1995 and March 2000 were included. Sensitivity to allergens, as determined by the skin prick test, was evaluated retrospectively. RESULTS: The files of a total of 3025 children (63.3 % boys) with bronchial asthma, aged 3 months to 16 years were evaluated. Of the total, 1667 patients with a diagnosis of bronchial asthma and 1358 with bronchial asthma plus allergic rhinitis were under follow-up. Of the 3025 asthmatic patients, 1902 had undergone the skin prick test and 60.3 % of these patients were atopic. The most common allergens were house dust mite [726 patients (63.3 %)], followed by pollens [565 patients (49.3 %)]. The most common allergen within this group was grass pollens [348 patients (30.3 %)]. CONCLUSIONS: Atopy was an important risk factor in our patients and the most common allergens were aeroallegens. The development of sensitization could be delayed by early precautions.