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1.
Actas esp. psiquiatr ; 46(5): 174-182, sept.-oct. 2018. tab, graf
Artigo em Espanhol | IBECS | ID: ibc-174685

RESUMO

Introducción. La Escala de Depresión Postnatal de Edimburgo (EPDS) es considerada el gold standard para el cribado de depresión postparto. Aunque la versión española ha sido ampliamente utilizada, su estructura factorial no ha sido todavía analizada. Metodología. Un total de 1.204 mujeres completaron la EPDS a las 32 semanas del parto. Para evitar pruebas múltiples dividimos la muestra en dos mitades de 602 participantes. Se realizó un análisis factorial exploratorio (AFE) con rotación oblimin con la primera sub-muestra. Posteriormente, con la segunda de las muestras se realizó un análisis factorial confirmatorio (AFC) mediante la estimación Weighted Least Squares Means and Variance (WLSMV). Se exploraron diferentes soluciones entre dos y cuatro factores. Comparamos los factores en dos grupos de participantes con depresión y sin depresión (evaluados con la Entrevista Diagnóstica para Estudios Genéticos (DIGS) para el DSM-IV). Resultados. El AFE mostró un modelo de tres factores compuesto por ansiedad, depresión y anhedonia. Los resultados del AFC confirmaron el modelo de tres factores (χ2=99,203, p<0,001; RMSEA=0,06, 90% CI=0,04/0,07, CFI=0,87 y TLI=0,82). Mujeres con depresión a las 32 semanas tuvieron puntuaciones más elevadas en ansiedad, depresión y anhedonia (p<0,001). Conclusiones. Primer estudio de análisis confirmatorio de la versión española de la EPDS, en una amplia muestra de mujeres sin tratamiento psiquiátrico durante el embarazo. Un modelo de tres factores compuesto por ansiedad, depresión y anhedonia ha sido obtenido. Mujeres con depresión tuvieron una mayor puntuación en las tres dimensiones de la EPDS


Introduction. The Edinburgh Postnatal Depression Scale (EPDS) is considered the gold standard in screening for postpartum depression. Although the Spanish version has been widely used, its factorial structure has not yet been studied. Methods. A total of 1,204 women completed the EPDS 32 weeks after delivery. To avoid multiple testing, we split the sample into two halves, randomly drawing two subsamples of 602 participants each. We conducted exploratory factor analysis (EFA), followed by an oblimin rotation with the first sub-sample. Confirmatory factor analysis (CFA) was conducted using a Weighted Least Squares Means and Variance (WLSMV) estimation of the data. We explored different solutions between two and four factors. We compared the factors between two groups with depression and non-depression (evaluated with the Diagnostic Interview for Genetic Studies (DIGS) for the DSM-IV). Results. The EFA indicated a three-factor model consisting of anxiety, depression and anhedonia. The results of the CFA confirmed the three-factor model (χ2=99.203, p<0.001) RMSEA=0.06, 90% CI=0.04/0.07, CFI=0.87 and TLI=0.82). Women with depression in the first 32 weeks obtained higher scores for anxiety, depression and anhedonia dimensions (p<0.0101). Conclusions. This is the first study of confirmatory analysis with the Spanish version of EPDS in a large sample of women without psychiatric care during pregnancy. A three-factor model consisting of anxiety, depression and anhedonia was used. Women with depression had a higher score in the three dimensions of the EPDS


Assuntos
Humanos , Feminino , Gravidez , Adulto , Depressão/epidemiologia , Análise Fatorial , Depressão Pós-Parto/epidemiologia , Escalas de Graduação Psiquiátrica , Transtornos de Ansiedade/epidemiologia , Depressão/psicologia , Depressão Pós-Parto/psicologia , Complicações na Gravidez/psicologia , Anedonia , Transtornos de Ansiedade/complicações , Transtornos de Ansiedade/psicologia
2.
An. psicol ; 24(1): 100-105, jun. 2008. tab
Artigo em Es | IBECS | ID: ibc-66535

RESUMO

El objetivo de este estudio es evaluar los niveles de sobrecarga, así como el estado de salud mental y física en los cuidadores de niños diagnosticados de autismo. También se analizarán la relación existente entre dichas variables. Han participado un total de 40 cuidadores, casi en su totalidad cuidadoras, obteniéndose medidas de factores sociodemográficos, sobrecarga (adaptación española de la escala de sobrecarga de Zarit), psicopatología (SCL-90) y estado de salud (SF-36).Los resultados indican una elevada sobrecarga en los cuidadores, así como una peor salud mental y física respecto de la población general. Se encuentran correlaciones positivas y significativas entre los niveles de sobrecarga y las dimensiones psicopatológicas y de salud evaluadas. Dichos resultados son consistentes con estudios previos en este campo. Se apoya la idea de la necesidad de programas de atención y apoyo para los cuidadores de niños con enfermedades crónicas


The objective of this study was to evaluate if caregivers were overloaded when their children were diagnosed with autism disorder, how it may influence their mental and physical health. 40 caregivers have been participating in this study, mainly mothers. The parameters studied include sociodemographic factors, caregivers burden overload (Zarit Scale, adapted to the Spanish language), Psychopathology (SCL-90) and health status (SF-60).The results indicate that caregivers were overloaded, and in a worse state of mental and physical health compared to the general population. A strong positive correlation was observed between overwhelmed carers and the evaluated health and pathopsicological parameters. These results are in accordance with previous findings that were published by other groups, supporting the idea that specific health programs are needed for caregivers of children with chronic diseases


Assuntos
Humanos , Masculino , Feminino , Criança , Adulto , Pessoa de Meia-Idade , Transtorno Autístico/enfermagem , Estresse Psicológico/psicologia , Cuidadores/psicologia , Nível de Saúde
3.
Genet. mol. biol ; Genet. mol. biol;25(1): 01-06, 2002. tab, graf
Artigo em Inglês | LILACS | ID: lil-324978

RESUMO

Fragile X syndrome is the most common inherited form of mental retardation. We investigated the prevalence of the Fragile X syndrome in the population with mental retardation of unknown etiology in Andalusia, South Spain. We analyzed 322 unrelated patients (280 males and 42 females), and found a fragile X syndrome frequency of 6.5 percent. Among the non-fragile X chromosomes, the 29 CGG repeat was the most common allele. At the linked microsatellite DXS548 locus, we found a new allele which we called "allele 10" (17 CA). Similar to other south European populations, allele 2 (25 CA) at the DXS548 locus and the fragile X allele were in linkage disequilibrium supporting the idea of a common founder chromosome predisposing to the CGG expansion


Assuntos
Humanos , Masculino , Feminino , Deficiência Intelectual , Síndrome do Cromossomo X Frágil/genética , Repetições de Trinucleotídeos , Efeito Fundador , Síndrome do Cromossomo X Frágil/etiologia , Espanha
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