Malignant hyperthermia in maxillofacial surgery: Literature review supported by case presentation.

OBJECTIVE: Malignant hyperthermia (MH) is characterized by a state of hypermetabolism after exposure to halogenated inhalational anesthetics or succinylcholine. The aims of this study were to carry out an updated review on the subject and report an illustrative case of MH in urgent maxillofacial surgery. MATERIAL AND METHODS: A search of the PubMed/MEDLINE database using the keyword "malignant hyperthermia" was performed including articles published over the last 11 years in English, Spanish or Portuguese. Exclusion criteria were similar presentations but not associated with MH and cases not related to the use of anesthetic drugs as a trigger of the condition. CASE REPORT: A 45-year-old man (75 kg, ASA status IE) with a negative family history for neuromuscular diseases, victim of a car accident with a facial fracture, underwent surgery under balanced general anesthesia and developed signs of MH 4 h after anesthesia induction. In our patient, the causative agent was sevoflurane and the diagnosis of MH was confirmed, subsequently, by muscle biopsy. RESULTS/DISCUSSION: Overall, 44 cases of MH were found. According to the recent literature, MH shows a male predilection (3:1) and the mean age of patients is 32.2 ± 22.2 years. The most frequently cited causative agents were sevoflurane (30.5%), isoflurane (22.2%), and sevoflurane + succinylcholine (13.8%). The most common clinical indicators included hypercarbia (88.8%), hyperthermia (86.1%), and tachycardia (63.8%). Dantrolene was administered in 24 cases. The outcome was favorable in 31 cases (86.1%). The in vitro muscle contracture test (IVCT) was performed in only 15 patients and all of them tested positive. In our patient, the causative agent was sevoflurane and the diagnosis of MH was confirmed by muscle biopsy. CONCLUSION: The mortality from MH is still high and an early clinical diagnosis and specific treatment with dantrolene are necessary for a favorable outcome. A complete understanding will allow better management of patients with MH. At present, the best management is to identify susceptible patients and to avoid triggering agents, combined with vigilant monitoring.

Complications associated with submental liposuction: a scoping review

Background: Liposuction is one of the most commonly performed cosmetic procedures worldwide. Complications associated with submental liposuction are rare. However, when they occur they are significant and can cause disFiguring consequences. The objective of this study was evaluated complications from submentual liposuction in literature and description of clinical experience of complication after submentual liposuction. Material and Methods: At first, a scoping review was carried out online search with no time restrictions for complications after submental liposuction was performed in the databases Medline / PubMed, Embase, and Web of Science. The variables analyzed were: age, sex, type of esthetic procedure, anesthesia, complications, time after Procedure, treatment, follow-up care, and sequelae. Then, a case of a patient with submental hematoma after an aesthetic procedure for submental liposuction was described. Results: Firstly, 539 articles were selected, after application of the inclusion criteria, 4 studies were included. Most cases were female (8:1), with a mean age of 55.77 years. Postoperative complications were found, such as submental depression, submental edema, hypertrophic scar formation, scar contracture, cervical necrotizing fasciitis, Cervico-facial dystonia and transient facial nerve paralysis. The follow-up period for cases ranged from 3 to 12 months. The clinical case presented there was no sequelae. Conclusions: Submental liposuction requires the surgeon's attention. Anatomical knowledge, correct clinical and surgical management, diagnosis, and immediate approach to adverse situations are points that must be respected in this type of esthetic procedure to avoid more serious complications.(AU)

Ressecção segmentar de granuloma central de células gigantes: relato de caso / Segmentation of central giant cell granuloma: case report

O Granuloma central de células gigantes é próprio dos ossos gnáticos, sendo um tumor benigno não odontogênico. É uma lesão de crescimento normalmente lento, bem circunscrito e assintomático, geralmente diagnosticado através de algum exame de rotina ou, em casos mais avançados, quando se começa a visualizar alguma alteração estético-anatômica. O tratamento de eleição para este tipo de lesão é a simples curetagem ou a ressecção em bloco. No entanto, em pacientes adultos jovens e em crianças, o efeito mutilante que este tipo de tratamento pode acarretar deve ser levado em consideração, utilizando tratamentos não cirúrgicos, como injeção intralesional de corticosteroides, administração de interferon alpha e calcitonina. Assim, o objetivo deste trabalho é relatar um caso de tratamento com ressecção segmentar de granuloma central de células gigantes. Tumores mais agressivos e recorrentes devem ser submetidos à ressecção e mesmo assim deve se levar em consideração o efeito estético que pode causar na face do paciente, principalmente, se forem crianças e adultos jovens... (AU)

The central granuloma of giant cells is specific to gnathic bones, being a benign non-odontogenic tumor. It's a growth injury usually slow, well circumscribed and asymptomatic, usually diagnosed through some routine examination or, in more advanced cases, when it begins to visualize some aesthetic-an atomical alteration. The treatment of choice for this type of injury is a simple curettage or resection in block. However, in young adult patients and children, the mutilating effect that this type of treatment can bring must be taken in to consideration, using non-surgical treatments, such as intralesional injection of corticosteroids, administration of alpha interferon and calcitonin. Therefore, the objective of this work is to report a case of treatment with resection segment of central granuloma of giant cells. More aggressive and recurrent tumors must be submitted to resection and even then taking into account the aesthetic effect it can have on the patient's face, especially if they are children and young adults... (AU)

Reconstrução mandibular com enxerto livre de crista ilíaca: relato de caso / Mandibular reconstruction with iliac crest free graft: case report

Os defeitos ósseos nos maxilares podem ser causados por patologias como ameloblastoma, carcinoma de células escamosas e sarcomas, bem como, por traumatismos faciais que vão desde acidentes de trânsito a agressões por arma de fogo. As reconstruções de tais defeitos ósseos não deverão apenas devolver a anatomia e contorno da região, mas também, restabelecer a estética e função. A escolha do melhor tipo de enxerto para reconstrução mandibular deverá ser feita de acordo com a característica do defeito e, principalmente, a observação do seu tamanho. O presente trabalho relata o caso clínico de um paciente que procurou o serviço de CTBMF do Hospital da Restauração, queixando-se de deformidade em terço inferior de face após agressão por projétil de arma de fogo (PAF) há, aproximadamente, 2 anos. Ao exame físico apresentava perda de continuidade óssea em região de parassínfise mandibular direita, oclusão pouco funcional e com prometimento funcional. Para o caso foi proposta cirurgia para reconstrução do defeito mandibular com enxerto livre de crista ilíaca. Diante disso, um diagnóstico preciso, planejamento minucioso e boa execução da técnica de reconstrução mandibular com enxerto livre de crista ilíaca proporcionam resultados estéticos satisfatórios, contorno e volume ósseos adequados possibilitando um restabelecimento funcional da área receptora... (AU)

Bone defects in the jaws can be caused by pathologies such as ameloblastoma, squamous cell carcinoma, and sarcomas, as well as facial trauma ranging from traffic accidents to gunshot wounds. Reconstructions of such bone defects should not only restore the anatomy and contour of the region, but also restore aesthetics and function. The choice of the best graft type for mandibular reconstruction should be made according to the characteristic of the defect and, especially, the observation of its size. The present study reports the clinical case of a patient who sought the CTBMF service of the Hospital da Restauração, complaining of deformity in the lower third of the face after aggression by FAP for approximately 2 years. Physical examination showed loss of bone segment in a region of right mandibular paresis, malocclusion and functional impairment. For the case, surgery was proposed to reconstruct the mandibular defect with free iliac crest graft. Therefore, a precise diagnosis, careful planning and good execution of the mandibular reconstruction technique with free iliac crest graft provide satisfactory aesthetic results, adequate bone contour and volume allowing a functional reestablishment of the receiver area... (AU)

Surgical Management of Odontogenic Infection in Sturge-Weber Syndrome: Report of a Case.

ABSTRACT: Surgical management of odontogenic infections in Sturge-Weber Syndrome is challenging, due to the risk of massive bleeding and difficulty to achieve hemostasis. The authors describe the use of preoperative vascular embolization for oral surgery in a 29-year-old patient. The authors highlight the importance of hemostatic agents and primary wound closure and the role of vascular embolization as a potential tool for preventing hemorrhage in these cases.

Reconstruction of Posttraumatic Nasal Defect Through Paramedian Frontal Flap.

ABSTRACT: Facial injuries caused by motorcycle accidents represent a challenge for reconstructions. Currently, the most indicated treatment for facial fractures is anatomical reduction and internal fixation, however, this procedure is not exempt from complications, such as infection and exposure of osteosynthesis material, thus requiring a new surgical procedure and repair. In this study, the authors describe a case of a 60-year-old woman who was the victim of a motorcycle accident and developed exposure of osteosynthesis material on the nasal dorsum after treatment of facial fractures. The patient underwent surgical treatment with objective of removing the osteosynthesis material and associated infected tissue, as well as reconstruction using a paramedian frontal flap, which resulted in a harmonic relationship and skin color similar to the recipient area. This case shows the importance of anatomical knowledge and reconstructive techniques for hard and soft tissues.

Management of chronic suppurative osteomyelitis in a patient with pycnodysostosis.

Pycnodysostosis is a rare bone dysplasia that causes changes in the facial skeleton. Osteomyelitis is common in patients with this syndrome, and, among the gnathic bones, the mandible is the most commonly affected. This case report describes the treatment of a 46-year-old woman with pycnodysostosis that was associated with chronic suppurative osteomyelitis of 5 years' duration. The patient had no intraoral focus of infection or history of tooth extraction that would explain the clinical findings of pain and a left-sided submandibular fistula. After the patient received 8 days of antibiotic therapy consisting of ceftriaxone and metronidazole, surgical access was achieved through the left submandibular region, and biopsy and curettage of the lesion and excision of the associated fistula were performed. At the 2-year follow-up examination, there was no evidence of lesion recurrence.

Surgical Management of Gunshot Injury to the Temporomandibular Joint.

One of the indications of the surgical approach of the temporomandibular joint is the presence of foreign body in its interior. However, joint handling offers risks, especially bleeding. In these cases, angiography and embolization of the arteries involved with the projectile play an important role in the prevention of complications. In this report, the authors describe a case of a 23-year-old male victim of firearm attack with comminuted fracture of the right mandibular condyle. The patient underwent angiography and prophylactic embolization of the arteries adjacent to the foreign body. A surgical procedure was performed to remove the projectile and bone fragments with the aid of the X-ray image intensifier, which resulted in the restoration of mandibular function, absence of joint pain, and satisfactory dental occlusion. This case shows the importance of auxiliary imaging methods for performing a safe surgical procedure for removal of ballistic and bony fragments from the interior of the temporomandibular joint.

Prescrição de medicamentos para tratamento da dor por estudantes da Faculdade de Odontologia de Pernambuco - FOP/UPE / Prescription medicines for treatment of pain for students of Pernambuco Dentistry College - FOP/UPE

Introdução: Avaliar o nível de conhecimento dos estudantes de Graduação em Odontologia da FOP em relação aos medicamentos que são prescritos para tratamento da dor leve e moderada. Metodologia: Estudo prospectivo, descritivo, de corte transversal, com abordagem quantitativa por meio de coleta de dados. Seguindo a metodologia proposta por Silva¹, o nível de conhecimento dos estudantes foi classificado em: 1 ­ nível bom; 2 ­ nível regular e 3 ­ nível insuficiente, mostrando que o estudante não está em condições de prescrever os medicamentos para tratar dor de forma segura. Resultados: Verificouse que 100% da amostra souberam indicar corretamente uma medicação para tratar a dor leve, e 93% indicaram na posologia correta. Entretanto, apenas 48% dos entrevistados tinham conhecimento do princípio ativo da droga prescrita. A maioria dos estudantes demonstrou conhecimento insatisfatório quanto à contraindicação e possíveis interações medicamentosas. Conclusões: Os estudantes prescrevem medicações para tratar dor; a maioria dos estudantes demonstrou conhecimento satisfatório quanto à indicação da droga e respectiva posologia para manejo da dor leve e moderada, no entanto a maior parte demonstrou conhecimento insatisfatório quanto à contraindicação e possíveis interações medicamentosas em relação aos medicamentos prescritos para tratar dor leve e moderada... (AU)

Introduction: To evaluate the level of knowledge of dental undergraduate students of FOP in relation to medications that are prescribed for the treatment of mild and moderate pain. Methodology: Prospective, descriptive cross-sectional study with a quantitative approach through data collection. Following the methodology proposed by Silva¹, the students' level of knowledge was classified as: 1 - good level; 2 - regular level and 3 - insufficient level, shows that the student is not in a position to prescribe drugs to treat pain safely. Results: It was verified that 100% of the sample was able to correctly indicate a medication to treat mild pain and 93% indicated in the correct dosage. However, only 48% of the interviewees were aware of the active principle of the prescribed drug. Most students demonstrated unsatisfactory knowledge regarding contraindication and possible drug interactions. Conclusions: Students prescribe medications to treat pain; the majority of students demonstrated satisfactory knowledge regarding the indication of the drug and its dosage for the management of mild and moderate pain. However, most demonstrated unsatisfactory knowledge regarding contraindication and possible drug interactions over prescribed drugs to treat mild and moderate pain... (AU)