[Intestinal mucosa absorption and esterification of 14C oleic acid during treatment with neomycin]. / Assorbimento ed esterificazione di acido oleico C14 nella mucosa intestinale del ratto durante trattamento con neomicina.

Neomycin administered to rats subjected to lymphatic fistula and treated with 14C-labelled oleic acid did not decrease either the absorption or the esterification of this organic acid. The results appear to indicate that neomycin has no effect on the intestinal mucosa.

[14C-labelled triolein absorption and esterification in rats treated with neomycin]. / Assorbimento ed esterificazione di trioleina C14 in ratti trattati con neomicina mediante fistola linfatica.

Intragastrically administered 14C-triolein was observed in fistula-derived lymph from rats treated with neomycin and controls. Absorption was much reduced in the treated animals, indicating (contrary to the literature data) that neomycin malabsorption also occurs in this species. The slight amount absorbed followed normal routes. It is suggested that the antibiotic acts on the intestinal content and not on the mucosa.