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1.
Bioengineering (Basel) ; 9(1)2022 Jan 01.
Artigo em Inglês | MEDLINE | ID: mdl-35049721

RESUMO

Orthodontic implants have been developed for the implementation of skeletal anchorage and are effectively used in the design of individual orthodontic devices. However, despite a significant amount of clinical research, the biomechanical aspects of the use of skeletal anchorage have not been adequately studied. The aim of this work was to numerically investigate the stress-strain state of the developed palatal orthodontic device supported by mini-implants. Four possible options for the placement of mini-implants in the bone were analyzed. The effect of a chewing load of 100 N on the bite plane was investigated. The study was carried out using biomechanical modeling based on the finite element method. The installation of the palatal orthodontic device fixed on mini-implants with an individual bite plane positioned on was simulated. The dependence of equivalent stresses and deformation changes on the number and location of the supporting mini-implants of the palatal orthodontic device was investigated. Two materials (titanium alloy and stainless steel) of the palatal orthodontic device were also investigated. The choice of a successful treatment option was based on the developed biomechanical criteria for assessing the surgical treatment success. Application of the criteria made it possible to estimate the stability and strength of fixation of each of the considered mini-implants installation options. As a result, options for the mini-implants optimal placement were identified (the first and the fourth which provide distributed front and side support of the device), as well as the preferred material (titanium alloy) for the manufacture of the palatal orthodontic device.

2.
Acta Bioeng Biomech ; 18(2): 9-17, 2016.
Artigo em Inglês | MEDLINE | ID: mdl-27406681

RESUMO

PURPOSE: Approximately 5% of the adult population has one or more cerebral aneurysm. Aneurysms are one of the most dangerous cerebral vascular pathologies. Aneurysm rupture leads to a subarachnoid hemorrhage with a very high mortality rate of 45-50%. Despite the high importance of this disease there are no criteria for assessing the probability of aneurysm rupture. Moreover, mechanisms of aneurysm development and rupture are not fully understood until now. METHODS: Biomechanical and numerical computer simulations allow us to estimate the behavior of vessels in normal state and under pathological conditions as well as to make a prediction of their postoperative state. Biomechanical studies may help clinicians to find and investigate mechanical factors which are responsible for the initiation, growth and rupture of the cerebral aneurysms. RESULTS: In this work, biomechanical and numerical modeling of healthy and pathological cerebral arteries was conducted. Patient-specific models of the basilar and posterior cerebral arteries and patient-specific boundary conditions at the inlet were used in numerical simulations. A comparative analysis of the three vascular wall models (rigid, perfectly elastic, hyperelastic) was performed. Blood flow and stress-strain state of the two posterior cerebral artery aneurysm models was compared. CONCLUSIONS: Numerical simulations revealed that hyperelastic material most adequately and realistically describes the behavior of the cerebral vascular walls. The size and shape of the aneurysm have a significant impact on the blood flow through the affected vessel and on the effective stress distribution in the aneurysm dome. It was shown that large aneurysm is more likely to rupture than small aneurysm.


Assuntos
Hemodinâmica , Aneurisma Intracraniano/fisiopatologia , Estresse Mecânico , Pressão Sanguínea/fisiologia , Artérias Carótidas/fisiopatologia , Diástole/fisiologia , Humanos , Modelos Biológicos , Fluxo Sanguíneo Regional , Sístole/fisiologia , Artéria Vertebral/fisiopatologia
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