[Comparative double blind study of pirprofen, indomethacin, and placebo in the treatment of osteoarthritis of the spine]. / Etude comparative en double insu du pirprofène, de l'indométacine et d'un placebo dans le traitement de l'arthrose vertébrale.

137 out-patients suffering from osteoarthritis of the spine were treated for two-weeks by pirprofen (600 mg/day), indomethacin (75 mg/day), or placebo. At the end of the trial, spontaneous pain disappeared in 47% of patients in the pirprofen group, 38% in the indomethacin group, and 17% in the placebo group. The efficacy of pirprofen and indomethacin, compared to the placebo, is demonstrated with respect to both spontaneous pain (p less than 0,01) and functional disorders (p less than 0,05). Side effects, especially digestive, were noted in 29% of patients treated by pirprofen, 33% of those treated by indomethacin and 17% of those on placebo. Tolerance was satisfactory in 86%, 80% and 90% of patients. Pirprofen is thus judged an effective drug for the treatment of osteoarthritis of the spine.

[Upper tibial osteotomy for gonarthrosis in geriatric patients (author's transl)]. / Die hohe Tibiaosterotomie in de Behandlung de Gonarthrose bei Betagten.

In gonarthrosis with unicompartmental prevalence showing either varus or valgus deformity a correction of the leg-axis is indicated even at old age. The upper transcondylar osteotomy is technically simple and easely tolerated. Weight bearing of the operated leg should be avoided during 6 weeks. A follow-up study of 78 patients aged 70 and more years was performed at an average time of 3 years postoperatively. A good pain releave was found in 78% and an objective improvement in walking capacity in 73%. It is the autors impression that tibial osteotomy has a better prognosis than endoprostetic replacement.