Antiplatelet therapy in patients undergoing oral surgery: A systematic review and meta-analysis.

BACKGROUND: The number of patients under antiplatelet therapy (APT) continues to raise as current recommendations foster this practice. Although some recommendations to manage this treatment during oral surgery procedures exist, these have methodological shortcomings that preclude them from being conclusive. MATERIAL AND METHODS: A systematic review and meta-analysis of the best current evidence was carried out; The Cochrane Library, EMBASE and MEDLINE databases were searched for Randomized Controlled Trials (RCT) concerning patients undergoing oral surgery with APT, other relevant sources were searched manually. RESULTS: 5 RCTs met the Inclusion criteria. No clear tendency was observed (RR= 0.97 CI 95%: 0,41-2,34; p=0,09; I2= 51%), moreover, they weren't clinically significant. CONCLUSIONS: According to these findings and as bleeding is a manageable complication it seems unreasonable to undermine the APT, putting the patient in danger of a thrombotic event and its high inherent morbidity, which isn't comparable in severity and manageability to the former."

Maxillofacial Mazabraud's syndrome: A case report & review.

Mazabraud's syndrome is characterized by myxomas of intramuscular type present in association with fibrous dysplasia. Up to this day, approximately 80 cases of Mazabraud's syndrome have been reported, although in the head and neck territory intramuscular myxoma reports in association with fibrous dysplasia of the bone are very scarce. An unusual case of Mazabraud's syndrome in a 63 years old female displaying fibrous dysplasia of the mandible and soft tissue myxoma in the edentulous alveolar ridge in the molar area is reported. After four years of follow-up, the clinical, imagenological and microscopical findings that led to the diagnosis and treatment are discussed. This report exemplifies the diagnostic and treatment challenge of this rare disease and enhances our clinical knowledge due to its long follow-up, highlighting the need of understanding better its behavior in order to establish proper guidelines for its treatment.