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1.
Polymers (Basel) ; 14(21)2022 Oct 31.
Artigo em Inglês | MEDLINE | ID: mdl-36365625

RESUMO

PTFE/Al reactive material is an energetic material that releases energy under impact conditions, resulting in a wide range of application prospects. In order to improve its damage ability-considering the higher heat of the reaction per unit mass when Ni2O3 is involved in the aluminothermic reaction-we designed and studied PTFE/Al/Ni2O3, a reaction material based on polytetrafluoroethylene (PTFE). We also designed two other kinds (PTFE/Al, PTFE/Al/CuO) for comparative study, with the mass fraction of the metal oxides added at 10%, 20%, and 30%, respectively. The quasi-static compression properties and impact initiation behavior of the material were investigated by a universal material testing machine and a drop hammer test. The reaction process of different materials under a high strain rate was recorded using a high-speed camera. The results show that with the increase in Ni2O3 content, the strength of the PTFE/Al/Ni2O3 reactive material shows an increasing trend followed by a decreasing trend. Among the three reactive materials, when the content of Al/Ni2O3 reaches 30 wt.%, the reaction duration is the longest (at 4 ms) and the reaction fireball is the largest. The addition of Ni2O3 is helpful to improve the reactivity and reaction duration of the PTEF/Al reactive material.

2.
Artigo em Chinês | WPRIM (Pacífico Ocidental) | ID: wpr-1008483

RESUMO

There are many chemical components in the volatile oil of Dictamni Cortex. The complex network relationship of "component-target-disease" can be revealed by using the network pharmacology method, and the mechanism of the efficacy of Dictamni Cortex can be revealed. In this study, we used Swiss Target Prediction database to predict the target of action, STRING database to build protein interaction network, and Cytoscape software to build "component-target-disease" network. The results showed that the antibacterial, anti-inflammatory and antiallergic effects of Dictamni Cortex were closely related to the components of thymol methyl ether, elemenol, anethole, and the related targets of each component were cross-linked to play a multi-target pharmacodynamic role. This study laid a foundation for the study of the effective substance basis and quality control evaluation of the Dictamni Cortex, and provided a scientific basis for further revealing its mechanism.


Assuntos
Dictamnus/química , Medicamentos de Ervas Chinesas/farmacologia , Óleos Voláteis/farmacologia , Mapas de Interação de Proteínas , Controle de Qualidade , Software
3.
Skin Res Technol ; 14(1): 45-52, 2008 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-18211601

RESUMO

BACKGROUND/PURPOSE: The efficacy of cosmetics on human skin measured under normal mild laboratory environment might be discounted by exterior environment factors such as wind, UV exposure, etc. Few studies have focused on the 'genuine' efficacy of cosmetics on human skin during exposure to external rigorous environment. The aim of this study was to develop a model for the evaluation of the efficacy of cosmetics on human skin under simulated rigorous environment. METHODS: We measured skin water content and transepidermal water loss (TEWL) before and after products application under simulated windy and sub-erythema UV exposure treatment in a constant temperature and humidity laboratory. RESULTS: The results showed that the products had higher water content and lower TEWL at 2, 4 and 8 h of products application, and ameliorated the skin moisturization situation after a 3-week continuous use of the products. In addition, the products might protect the skin to maintain the normal water content and TEWL under the simulated windy or sub-erythema UV exposure treatment in our laboratory when compared with untreated area. CONCLUSION: Our data indicate that this model may provide a more accurate evaluation for the genuine moisturizing effect of cosmetics under external natural climate.


Assuntos
Cosméticos/farmacologia , Emolientes/farmacologia , Fenômenos Fisiológicos da Pele , Pele/efeitos dos fármacos , Adulto , Bochecha/fisiologia , Cosméticos/farmacocinética , Capacitância Elétrica , Emolientes/farmacocinética , Ambiente Controlado , Feminino , Antebraço/fisiologia , Humanos , Pele/efeitos da radiação , Raios Ultravioleta , Perda Insensível de Água , Vento
4.
Wei Sheng Yan Jiu ; 35(6): 811-3, 2006 Nov.
Artigo em Chinês | MEDLINE | ID: mdl-17290775

RESUMO

With the fast development of cosmetics research, the adverse skin reactions induced by cosmetics allergy has attracted more and more attention of researchers. The article briefly introduces the causes and classifications of cosmetics allergy, and presents in detail the internal and international development of cosmetics allergy analysis and evaluation methods, including in vivo patch test, in vitro epidermis equivalents test, skin stratum hydration test, skin transepidermal water loss (TEWL) test, skin redness test, etc. Also, the future developing trend for cosmetics allergy prevention and cure is discussed here. The article will provide a technical reference for the future healthy development of cosmetics in China.


Assuntos
Cosméticos/efeitos adversos , Dermatite Alérgica de Contato/diagnóstico , Dermatite Alérgica de Contato/classificação , Dermatite Alérgica de Contato/etiologia , Humanos , Testes Cutâneos
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