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1.
J Fr Ophtalmol ; 41(7): 659-668, 2018 Sep.
Artigo em Francês | MEDLINE | ID: mdl-30173871

RESUMO

Arboviruses are viral diseases transmitted by mosquitoes and tics bites. They are a major cause of morbidity and sometimes mortality. Their expansion is constant and due in part to climate change and globalization. Mostly found in tropical regions, arboviruses are sometimes the source of epidemics in Europe. Recently, the Chikungunya virus and the Zika virus were responsible for very large epidemics impacting populations that had never been in contact with those viruses. There are currently no effective antiviral treatments or vaccines. Ocular manifestations due to those infections are thus more frequent and increasingly better described. They are sometimes, as with Zika, complicated by a congenital ocular syndrome. The goal of this review is to describe the ophthalmological manifestations of Dengue fever, Chikungunya virus, Zika virus, West Nile virus, and yellow fever.


Assuntos
Infecções por Arbovirus/diagnóstico , Doenças Transmissíveis Emergentes/diagnóstico , Infecções Oculares Virais/diagnóstico , Infecções por Arbovirus/complicações , Infecções por Arbovirus/epidemiologia , Arbovírus/fisiologia , Febre de Chikungunya/complicações , Febre de Chikungunya/diagnóstico , Febre de Chikungunya/epidemiologia , Doenças Transmissíveis Emergentes/complicações , Doenças Transmissíveis Emergentes/epidemiologia , Dengue/complicações , Dengue/diagnóstico , Dengue/epidemiologia , Infecções Oculares Virais/epidemiologia , Infecções Oculares Virais/virologia , Humanos , Febre Amarela/complicações , Febre Amarela/diagnóstico , Febre Amarela/epidemiologia , Infecção por Zika virus/complicações , Infecção por Zika virus/diagnóstico , Infecção por Zika virus/epidemiologia
2.
J Fr Ophtalmol ; 41(6): e235-e243, 2018 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-29929827

RESUMO

Arboviruses are viral diseases transmitted by mosquitoes and tick bites. They are a major cause of morbidity and sometimes mortality. Their expansion is constant and due in part to climate change and globalization. Mostly found in tropical regions, arboviruses are sometimes the source of epidemics in Europe. Recently, the Chikungunya virus and the Zika virus were responsible for very large epidemics impacting populations that had never been in contact with those viruses. There are currently no effective antiviral treatments or vaccines. Ocular manifestations due to those infections are thus more frequent and increasingly better described. They are sometimes, as with Zika, complicated by a congenital ocular syndrome. The goal of this review is to describe the ophthalmological manifestations of Dengue fever, Chikungunya virus, Zika virus, West Nile virus, and yellow fever.


Assuntos
Infecções por Arbovirus , Infecções Oculares Virais/epidemiologia , Infecções Oculares Virais/virologia , Infecções por Arbovirus/diagnóstico , Infecções por Arbovirus/epidemiologia , Infecções por Arbovirus/virologia , Arbovírus/classificação , Arbovírus/isolamento & purificação , Febre de Chikungunya/complicações , Febre de Chikungunya/diagnóstico , Febre de Chikungunya/epidemiologia , Vírus Chikungunya/isolamento & purificação , Vírus Chikungunya/fisiologia , Doenças Transmissíveis Emergentes/diagnóstico , Doenças Transmissíveis Emergentes/epidemiologia , Doenças Transmissíveis Emergentes/virologia , Dengue/complicações , Dengue/diagnóstico , Dengue/epidemiologia , Infecções Oculares Virais/diagnóstico , Humanos , Vírus do Nilo Ocidental/isolamento & purificação , Vírus do Nilo Ocidental/fisiologia , Febre Amarela/complicações , Febre Amarela/diagnóstico , Febre Amarela/epidemiologia , Zika virus/isolamento & purificação , Zika virus/fisiologia , Infecção por Zika virus/complicações , Infecção por Zika virus/diagnóstico , Infecção por Zika virus/epidemiologia
5.
J Fr Ophtalmol ; 36(3): e41-3, 2013 Mar.
Artigo em Francês | MEDLINE | ID: mdl-23238074

RESUMO

We report a case of unsuspected penetrating trauma with intraorbital foreign body, namely a needlefish jaw. A 44-year-old fisherman presented with vertical diplopia and discrete swelling of the upper lid near the medial canthus after being hit by a fish. He was unaware of any penetrating lesion or foreign body. There was no entry wound. CT-scan showed a foreign body between the globe and the medial orbital wall. Surgical exploration found that it was a 4.5cm long needlefish jaw. Removal resulted in complete resolution of symptoms. Needlefish can be very dangerous. This is the first reported case of a needlefish jaw in the orbit with no associated lesion, infection or inflammation.


Assuntos
Beloniformes , Corpos Estranhos no Olho/diagnóstico , Traumatismos Oculares/diagnóstico , Traumatismos Ocupacionais/diagnóstico , Adulto , Animais , Dacriocistite/diagnóstico , Diagnóstico Diferencial , Corpos Estranhos no Olho/diagnóstico por imagem , Traumatismos Oculares/diagnóstico por imagem , Traumatismos Oculares/etiologia , Humanos , Arcada Osseodentária , Masculino , Traumatismos Ocupacionais/diagnóstico por imagem , Traumatismos Ocupacionais/etiologia , Órbita/diagnóstico por imagem , Órbita/lesões , Radiografia
6.
J Fr Ophtalmol ; 35(10): 824.e1-6, 2012 Dec.
Artigo em Francês | MEDLINE | ID: mdl-23022342

RESUMO

Three Afro-Caribbean women presented with a decreased visual acuity associated with preeclampsia during the third trimester of pregnancy. Fundus examination exhibited a serous retinal detachment (SRD). Postpartum fluorescein and indocyanine green angiography indicated subretinal leakage induced by choroidal ischemia. The three patients had an improvement of their visual acuity to 20/20 within 2 to 3 months of the onset of symptoms. Fundus exam and fluorescein angiography showed no further abnormality. SRD in preeclampsia may have an impressive acute presentation but seems to resolve favorably spontaneously without intervention, upon delivery. Nevertheless, SRD must be considered to be a sign of imminent worsening of preeclampsia.


Assuntos
Pré-Eclâmpsia , Complicações na Gravidez/diagnóstico , Descolamento Retiniano/diagnóstico , Adulto , População Negra , Feminino , Angiofluoresceinografia , Humanos , Pré-Eclâmpsia/diagnóstico , Gravidez , Descolamento Retiniano/complicações , Índias Ocidentais , Adulto Jovem
7.
J Fr Ophtalmol ; 35(2): 124.e1-4, 2012 Feb.
Artigo em Francês | MEDLINE | ID: mdl-21824680

RESUMO

INTRODUCTION: Non-Hodgkin lymphomas (NHLs) constitute a group of heterogeneous diseases that can arise in lymphatic nodal or extranodal sites. Ocular lymphomas account for 1% of all NHLs. Tumor of the orbit, which can lead to compression of the optic nerve, is the most frequent presentation of the disease. Primary infiltration of the optic nerve and its sheath remains exceptional. OBSERVATION: We report the case of a 51-year-old female patient treated for a NHL. While she was considered to be in remission after four courses of chemotherapy, she presented a right visual loss with hand motion acuity. Her examination revealed a right afferent pupillary defect. Brain MRI emphasized an infiltration of her right optic nerve with no other orbit abnormality. Cerebrospinal fluid analysis showed lymphomatous meningitis. She was then considered to have lymphomatous optic neuropathy (LON). Despite initial improvement of the visual acuity with treatment, the patient died of bone marrow aplasia 6 weeks later. CONCLUSION: LON can be suspected in a painful and sudden visual loss in a context of neoplasia. The diagnosis is confirmed by MRI and cerebrospinal fluid analysis. LON may occur as the sole ocular manifestation of disease recurrence in a patient with systemic NHL, otherwise thought to be in clinical remission.


Assuntos
Neoplasias do Sistema Nervoso Central/secundário , Linfoma não Hodgkin/complicações , Linfoma não Hodgkin/patologia , Neoplasias Meníngeas/secundário , Doenças do Nervo Óptico/etiologia , Neoplasias do Sistema Nervoso Central/complicações , Neoplasias do Sistema Nervoso Central/diagnóstico , Feminino , Humanos , Neoplasias Meníngeas/complicações , Neoplasias Meníngeas/diagnóstico , Pessoa de Meia-Idade , Doenças do Nervo Óptico/complicações , Doenças do Nervo Óptico/diagnóstico , Neurite Óptica/diagnóstico , Neurite Óptica/etiologia , Acuidade Visual
9.
J Fr Ophtalmol ; 33(10): 701-9, 2010 Dec.
Artigo em Francês | MEDLINE | ID: mdl-21093961

RESUMO

INTRODUCTION: microbial keratitis is a significant health concern for the one million wearers of contact lenses and their ophthalmologists, with some potentially modifiable risk factors. The number of risk factors for contact lens-related microbial keratitis has been described, but many of them still remain assumed or unknown. PATIENTS AND METHODS: a multicenter prospective case-control study was conducted in 12 French university hospitals (Besançon, Bordeaux, Dijon, Fort-de-France, Grenoble, Limoges, Lyon, Nancy, Nantes, Paris, Marseille and Strasbourg) beginning in July 2007 on contact lens wearers presenting with microbial keratitis and on healthy contact lens wearers. Patients and healthy wearers were interviewed using a 51-item anonymous standardized questionnaire to determine subject demographics and contact lens wear history. RESULTS: two hundred and fifty-six patients with microbial keratitis were included. One hundred and thirteen healthy contact lenses wearers were surveyed. Cosmetic contact lens wear highly increased the relative risk (RR) of microbial keratitis (RR, 16.5). Time since the last visit to an ophthalmologist longer than 1 year (RR, 3.4) or prescription by someone other than an ophthalmologist (RR, 7.6) also increased the risk of microbial keratitis. Education on lens care and handling was deficient (hand washing: RR, 2.2; rub and rinse: RR, 2.7). DISCUSSION: a standardized questionnaire is a powerful tool to determine risk factors for contact lens-related microbial keratitis, but also to analyze individual mistakes in contact lenses use and care.


Assuntos
Lentes de Contato/efeitos adversos , Ceratite/microbiologia , Ceratite/prevenção & controle , Inquéritos e Questionários , Adulto , Estudos de Casos e Controles , Feminino , Humanos , Masculino , Estudos Prospectivos , Medição de Risco , Inquéritos e Questionários/normas
10.
J Fr Ophtalmol ; 33(4): 258-62, 2010 Apr.
Artigo em Francês | MEDLINE | ID: mdl-20223558

RESUMO

PURPOSE: To determine the characteristics of infectious keratitis related to plano cosmetic lenses. METHODS: Retrospective case study of a series of infectious keratitis among plano cosmetic lenses wearers. The main parameters were demographic data, medical history, risk factors for infectious complications and keratitis severity criteria, microbiological results, clinical course, and final visual acuity. RESULTS: Five patients were included, all females, ranging from 15 to 50 years of age. Four were emmetropic. One patient had undergone refractive photokeratectomy a few months before. All had risk factors for infectious complications. The fundamental causes of infections were diverse: bacterial abscesses, keratomycosis, and amoebic keratitis. All presented severity criteria. In two cases, the keratitis led to severe consequences with legal blindness requiring penetrating keratoplasty in one case. DISCUSSION: Infectious keratitis in plano cosmetic lenses wearers is not rare and may have dramatic consequences. Sales are specifically regulated and the lenses are considered cosmetic products, not medical devices. The sales regulations for plano cosmetic lenses should be updated, as several countries have already done after encountering many serious incidents.


Assuntos
Lentes de Contato/efeitos adversos , Ceratite/microbiologia , Abscesso/microbiologia , Ceratite por Acanthamoeba/parasitologia , Adolescente , Adulto , Antibacterianos/uso terapêutico , Anti-Infecciosos/uso terapêutico , Anti-Infecciosos Locais/uso terapêutico , Antifúngicos/uso terapêutico , Benzamidinas/uso terapêutico , Biguanidas/uso terapêutico , Cegueira/etiologia , Opacidade da Córnea/etiologia , Cirurgia da Córnea a Laser , Feminino , Gentamicinas/uso terapêutico , Humanos , Pessoa de Meia-Idade , Infecções por Pseudomonas/microbiologia , Pirimidinas/uso terapêutico , Estudos Retrospectivos , Fatores de Risco , Infecções por Serratia/microbiologia , Infecções Estafilocócicas/microbiologia , Ticarcilina/uso terapêutico , Triazóis/uso terapêutico , Vancomicina/uso terapêutico , Voriconazol , Adulto Jovem
11.
J Fr Ophtalmol ; 31(6 Pt 1): 579-84, 2008 Jun.
Artigo em Francês | MEDLINE | ID: mdl-18772808

RESUMO

OBJECTIVES: To clarify the clinical and angiographic characteristics of idiopathic polypoidal choroidal vasculopathy (IPCV) and its natural course. METHODS: Descriptive, prospective, consecutive case series of patients with presumed IPCV seen at Fort-de-France Hospital Center (French West Indies) between January and June 2006. All participants underwent complete eye examination and fluorescein and indocyanine green (ICG) angiography. The nature and location of the lesions were assessed in all eyes. Inclusion criteria were demonstration of characteristic lesions of IPCV on ICG angiography. RESULTS: Diagnosis of IPCV was made in 26 eyes of 14 patients, ten women and four men, all of Afro-Caribbean origin. The mean age was 77.4 years (range 60-92 years). Drusen were present in 13 eyes (50%), age-related macular degeneration (AMD) in one eye, and branch retinal vein occlusion in one eye. Twelve patients (85.7%) had bilateral involvement. Twelve eyes (46.2%) had visual acuity (VA) (Snellen) worse than 20/200, six eyes (23.1%) had VA between 20/200 and 20/100, and eight eyes (30.8%) had VA better than 20/100. On ICG angiography, lesions were predominantly located in the peripapillary area but also in the midperiphery, the macular and interpapillomacular areas, and the far periphery. CONCLUSION: Peripheral locations of IPCV and associations with drusen or AMD are not rare. The prognosis of the disease is poor in its natural course. Its etiology is unknown but genetic factors are probably involved. It is the main differential diagnosis for exudative AMD in black patients.


Assuntos
Doenças da Coroide/diagnóstico por imagem , Corioide/irrigação sanguínea , Idoso , Idoso de 80 Anos ou mais , Doenças da Coroide/complicações , Doenças da Coroide/etnologia , Doenças da Coroide/patologia , Dilatação Patológica/diagnóstico por imagem , Progressão da Doença , Etnicidade , Feminino , Fluoresceína , Angiofluoresceinografia , Humanos , Verde de Indocianina , Degeneração Macular/complicações , Degeneração Macular/diagnóstico por imagem , Masculino , Martinica/epidemiologia , Pessoa de Meia-Idade , Estudos Prospectivos , Radiografia , Drusas Retinianas/complicações , Drusas Retinianas/diagnóstico por imagem , Oclusão da Veia Retiniana/complicações , Oclusão da Veia Retiniana/diagnóstico por imagem , Acuidade Visual
12.
J Fr Ophtalmol ; 31(5): 533.e1-5, 2008 May.
Artigo em Francês | MEDLINE | ID: mdl-18641577

RESUMO

We report four cases referred to the Ophthalmologic Department of the University Hospital Center of Fort de France for the therapeutic management of a conjunctival malignant tumor. All cases reported involved conjunctival squamous cell carcinoma. All tumors were unilateral, one was localized, another was recurrent, one occurred in a patient with acquired immunodeficiency syndrome, and the last one was seen at the late stage of massive locoregional invasion. Three patients had surgery completed by corneolimbic cryotherapy. The last case was exentered. All of them consulted regularly. These four cases were collected over 5 years in approximately 15,000 patients examined per year in the University Hospital Center of Fort de France. Conjunctival squamous cell carcinoma is rare, even in Martinique, a tropical area. Careful attention to risk factors such as the sun exposure is recommended, as is the histologic diagnosis with any conjunctival tumour, since it changes quickly. The treatment must be adapted to the extension of the disease and to the patient's general health. The high rate of recurrence requires long-term follow-up in corneal and conjunctival intraepithelial neoplasia.


Assuntos
Carcinoma de Células Escamosas/terapia , Neoplasias da Túnica Conjuntiva/terapia , Idoso , Carcinoma de Células Escamosas/patologia , Terapia Combinada , Neoplasias da Túnica Conjuntiva/patologia , Feminino , Humanos , Pessoa de Meia-Idade , Recidiva , Luz Solar/efeitos adversos , Resultado do Tratamento , Raios Ultravioleta/efeitos adversos
13.
Eur J Ophthalmol ; 18(3): 456-8, 2008.
Artigo em Inglês | MEDLINE | ID: mdl-18465733

RESUMO

PURPOSE: To report a case of macular hole secondary to Bartonella henselae neuroretinitis. METHODS: Observational case report. An 11 year-old boy presented urgently with a decrease of visual acuity in the left eye. Posterior segment examination revealed neuroretinitis attributed to Bartonella henselae. Treatment was initiated, resulting in the disappearance of symptoms. RESULTS: Follow-up consultations 7 months later showed a further decline in visual acuity secondary to a macular hole. CONCLUSIONS: Cat scratch disease is a rare pathology and is most often considered benign. Serious complications can nonetheless occur, such as neuroretinitis, choroidal nodules, and disciform keratitis. The authors report a case of sequellar macular hole. They found only one previous report of macular hole caused by B henselae, which, contrary to their case, appeared rapidly 12 days after presentation.


Assuntos
Bartonella henselae/isolamento & purificação , Doença da Arranhadura de Gato/complicações , Infecções Oculares Bacterianas/complicações , Perfurações Retinianas/etiologia , Retinite/complicações , Antibacterianos/uso terapêutico , Anticorpos Antibacterianos/sangue , Bartonella henselae/imunologia , Doença da Arranhadura de Gato/diagnóstico , Doença da Arranhadura de Gato/tratamento farmacológico , Criança , Doxiciclina/uso terapêutico , Quimioterapia Combinada , Infecções Oculares Bacterianas/diagnóstico , Infecções Oculares Bacterianas/tratamento farmacológico , Técnica Indireta de Fluorescência para Anticorpo , Humanos , Imunoglobulina M/sangue , Masculino , Retinite/diagnóstico , Retinite/tratamento farmacológico , Rifampina/uso terapêutico , Acuidade Visual
15.
J Fr Ophtalmol ; 29(9): e25, 2006 Nov.
Artigo em Francês | MEDLINE | ID: mdl-17114988

RESUMO

INTRODUCTION: We report a case of unilateral leukemic infiltration of the optic nerve caused by acute lymphoblastic leukemia. CASE REPORT: A 30-year-old woman with acute lymphoblastic leukemia beginning 3 months before was referred for left visual loss. The left fundus showed optic disc engorgement by infiltrating tumor, with numerous hemorrhages and exudates caused by optic nerve leukemic infiltration. CONCLUSION: Optic nerve leukemic infiltration is considered as central nervous system damage with severe prognosis. Treatment is based upon systemic and intrathecal chemotherapy and central nervous system radiation.


Assuntos
Infiltração Leucêmica , Nervo Óptico/patologia , Leucemia-Linfoma Linfoblástico de Células Precursoras/patologia , Adulto , Feminino , Humanos
16.
Eur J Ophthalmol ; 16(5): 751-2, 2006.
Artigo em Inglês | MEDLINE | ID: mdl-17061229

RESUMO

PURPOSE: To report an unusual incident of isolated conjunctival ulcerations which preceded all other signs of Behçet's disease. METHODS: Description of a 34-year-old woman of West Indian origin with an unremarkable medical history presenting with bilateral bulbar conjunctival ulcerations. RESULTS: The authors noted the presence of a diffuse bilateral conjunctival hyperemia which was more pronounced at the temporal bulbar conjunctiva of the right eye and the nasal conjunctiva of the left eye, each having one ulceration. The rest of the ophthalmologic examination was normal. One month later, the appearance of buccogenital aphthosis led to the diagnosis of Behçet's disease. CONCLUSIONS: This observation is unusual, as the conjunctival ulcerations are isolated and precede the onset of all other symptoms of Behçet's disease. Conjunctival ulcerations are rarely seen with Behçet's disease, but are characteristic enough to be included among the diagnostic criteria.


Assuntos
Síndrome de Behçet/complicações , Doenças da Túnica Conjuntiva/etiologia , Úlcera/etiologia , Adulto , Síndrome de Behçet/patologia , Doenças da Túnica Conjuntiva/patologia , Diagnóstico Diferencial , Feminino , Seguimentos , Humanos , Úlcera/patologia
17.
J Fr Ophtalmol ; 29(2): e4, 2006 Feb.
Artigo em Francês | MEDLINE | ID: mdl-16523150

RESUMO

We report a case of endophthalmitis caused by the fungus Lasiodiplodia theobromae. A 68-year-old man was referred to the hospital for right ocular pain since experiencing right ocular branch trauma 2 weeks before. The best-corrected acuity was limited to hand motion. Slit-lamp examination showed a large corneal abscess and an anterior chamber reaction. The patient underwent systemic and local antibiotic therapy, and corneal scraping for microbiological diagnosis. Sabouraud-chloramphenicol-gentamicin agar disclosed filamentous fungus, which was treated with oral itraconazole and topic amphotericin B. Molecular biology revealed Lasiodiplodia theobromae. Despite antimycotic drugs, severe panophthalmia occurred very quickly and led to evisceration. This case report describes Lasiodiplodia theobromae as the cause of keratomycosis and discusses risk factors and clinical features of fungal keratitis in order to improve prognosis by earlier treatment.


Assuntos
Ascomicetos , Endoftalmite/microbiologia , Ceratite/microbiologia , Micoses , Idoso , Humanos , Masculino
18.
Eur J Ophthalmol ; 16(5): 751-752, 2006.
Artigo em Inglês | MEDLINE | ID: mdl-28221629

RESUMO

PURPOSE: To report an unusual incident of isolated conjunctival ulcerations which preceded all other signs of Behets disease. METHODS: Description of a 34-year-old woman of West Indian origin with an unremarkable medical history presenting with bilateral bulbar conjunctival ulcerations. RESULTS: The authors noted the presence of a diffuse bilateral conjunctival hyperemia which was more pronounced at the temporal bulbar conjunctiva of the right eye and the nasal conjunctiva of the left eye, each having one ulceration. The rest of the ophthalmologic examination was normal. One month later, the appearance of buccogenital aphthosis led to the diagnosis of Behets disease. CONCLUSIONS: This observation is unusual, as the conjunctival ulcerations are isolated and precede the onset of all other symptoms of Behets disease. Conjunctival ulcerations are rarely seen with Behets disease, but are characteristic enough to be included among the diagnostic criteria.

19.
Eur J Ophthalmol ; 15(3): 392-9, 2005.
Artigo em Inglês | MEDLINE | ID: mdl-15945010

RESUMO

PURPOSE: To describe the visual phenotype of multiple sclerosis (MS) in the Afro-Caribbean population living in Martinique (French West Indies) and to specify the influence of the migration to metropolitan France on ocular impairment. DESIGN: Prospective consecutive observational case series. METHODS: A complete ophthalmologic examination was performed. PARTICIPANTS: A total of 112 patients of Afro-Caribbean origin with MS satisfying McDonald's diagnostic criteria, divided into 53 cases (47.3%), the non-migrant patients (group NM), who had never left the Caribbean basin, and 59 cases (52.7%), the migrant patients (group M), who had lived in metropolitan France for at least 1 year before age 15. RESULTS: MS first manifested as an impairment of the optic nerve in 41 cases (36.6%): 25 cases (47.1%) in group NM and 16 cases (27.1%) in group M. Visual function was recovered in 13/25 cases (52%) in group NM compared to 13/16 cases (81%) in group M. Two-thirds of patients presented with a clinical ocular impairment, which was bilateral in 58.5% of cases in group NM. Fourteen cases (12.5%) met the criteria of neuromyelitis optica, nine cases (17%) in group NM and five cases (8.5%) in group M. In group NM, when the initial visual attack did not regress, the visual Expanded Disability Status Scale (EDSS) score was 5+/-1.5 ; 75% of patients had monocular blindness and 50% binocular. CONCLUSIONS: In the non-migrants (group NM), MS manifested more frequently with an optical neuropathy, the ocular impairment was more severe, and corresponded to neuromyelitis optica in 17% of the cases; a visual presentation and the absence of complete recovery from the first attack represented a factor of poor prognosis. This series is the largest description of the visual phenotype of MS in patients of African origin. The results confirm the preferential impairment of the optic nerve in the black population in the course of the disease. The migration towards an area of high prevalence of MS influences the visual phenotype in terms of a lower incidence and less severe prognosis of ocular impairment.


Assuntos
Negro ou Afro-Americano , Emigração e Imigração , Esclerose Múltipla/etnologia , Neurite Óptica/etnologia , Adulto , Região do Caribe/etnologia , Feminino , França/epidemiologia , Humanos , Incidência , Masculino , Esclerose Múltipla/patologia , Neurite Óptica/diagnóstico , Fenótipo , Prognóstico , Estudos Prospectivos , Acuidade Visual
20.
J Fr Ophtalmol ; 28(10): 1110-4, 2005 Dec.
Artigo em Francês | MEDLINE | ID: mdl-16395206

RESUMO

PURPOSE: Melanocytoma is a rare benign tumor that usually occurs as a pigmented lesion in the optic nerve head. It seems to be more frequently encountered in the Black population. We report three cases of melanocytoma observed in Martinique, where 90% of the population is of African origin. OBSERVATIONS: The first and second cases were found on routine ophthalmic examination. These patients had a heavily pigmented lesion that obscured part or all of the optic disc with slight extension into the adjacent nerve fiber layer of the retina. The tumor's margins were finely fibrillated. Fluorescein angiography demonstrated a homogenous hypofluorescent black tumor obscuring the optic disc vessels, with no tumor vessels visible. There were no juxtapapillary choroid vascular abnormalities. The third case was discovered on visual field examination. This melanocytoma was accompanied by papillary edema. CONCLUSION: Only three cases of melanocytoma have been noted from 1994 to 2004 in 150,000 Caribbean patients examined in the University Hospital Center of Fort de France. The rarity of melanoma and the predisposition to melanocytoma are important epidemiologic factors in the etiologic search for pigmented tumor within the Black population. Yearly fundus examination is useful for monitoring growth and detecting malignant transformation.


Assuntos
Nevo/diagnóstico , Disco Óptico , Neoplasias do Nervo Óptico/diagnóstico , Adulto , Feminino , Humanos , Masculino
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