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1.
Adv Mater ; 33(42): e2104497, 2021 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-34476854

RESUMO

Beryllium has long been predicted by first principle theory as the best p-type dopant for GaN and AlN. But experimental validation of these theories has not, until now, borne out the original predictions. A key challenge is the dopant-induced strain leading to Be rejection from substitutional sites in favor of interstitial sites, leading to self-compensation. More flexible growth methods like metal modulated epitaxy (MME) that can operate at substantially lower temperatures than traditional approaches, can more effectively place Be into the proper substitutional lattice sites. MME grown Be-doped AlN shows substantial p-type conductivity with hole concentrations in the range of 2.3 × 1015 -3.1 × 1018  cm-3  at room temperature. While others have achieved sizable carrier concentrations near surfaces via carbon doping or Si implantation, this is the only known demonstration of substantial bulk p-type doping in AlN and is a nearly 1000 times higher carrier concentration than the best previously demonstrated bulk electron concentrations in AlN. The acceptor activation energy is found to be ≈37 meV, ≈8 times lower than predicted in literature but on par with similar results for MME p-type GaN. Preliminary results suggest that the films are highly compensated. A p-AlN:Be/i-GaN:Be/n-GaN:Ge pin diode is demonstrated with substantial rectification.

2.
Science ; 365(6456): 897-902, 2019 08 30.
Artigo em Inglês | MEDLINE | ID: mdl-31467217

RESUMO

Environmentally transformative human use of land accelerated with the emergence of agriculture, but the extent, trajectory, and implications of these early changes are not well understood. An empirical global assessment of land use from 10,000 years before the present (yr B.P.) to 1850 CE reveals a planet largely transformed by hunter-gatherers, farmers, and pastoralists by 3000 years ago, considerably earlier than the dates in the land-use reconstructions commonly used by Earth scientists. Synthesis of knowledge contributed by more than 250 archaeologists highlighted gaps in archaeological expertise and data quality, which peaked for 2000 yr B.P. and in traditionally studied and wealthier regions. Archaeological reconstruction of global land-use history illuminates the deep roots of Earth's transformation and challenges the emerging Anthropocene paradigm that large-scale anthropogenic global environmental change is mostly a recent phenomenon.

3.
Proc Natl Acad Sci U S A ; 113(41): 11382-11383, 2016 10 11.
Artigo em Inglês | MEDLINE | ID: mdl-27679848
4.
Int J Circumpolar Health ; 64(4): 365-86, 2005 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-16277121

RESUMO

OBJECTIVES: To determine the prevalence of CVD and to identify and characterize associated risk factors in three distinct Eskimo populations. STUDY DESIGN: Cross-sectional. METHODS: A slightly modified Strong Heart Study protocol was followed to examine 454 participants, aged 25-91, from four villages. RESULTS: Overall, 6% of the participants under 55 years of age and 26% of those > or = 55 years of age showed evidence of CHD by ECG, or in patient records. The prevalence of "definite coronary heart disease" (CHD) in women with glucose intolerance (GI) was 21.0%, compared to 2.4% in those with normal glucose tolerance (NGT). Men had comparable values of 26.7% and 6.3%. In addition, comparable values for "possible CHD" were 29.7% vs 6.0% for women and 21.4% vs 8.0% for men. GI was associated with relatively higher prevalences of CHD in women than in men (prevalence ratio = 8.5 vs 4.3). CHD was significantly related to age, glucose intolerance and insulin. Hypertension and obesity were significantly associated with CHD only in some ethnic groups. The prevalence of current smokers was 56%. CONCLUSIONS: Recent changes in lifestyle and diet of Alaskan Eskimos, leading to obesity, hypertension, insulin resistance and DM, contribute to an increased risk for cardiovascular disease.


Assuntos
Doenças Cardiovasculares/etnologia , Inuíte/estatística & dados numéricos , Adulto , Distribuição por Idade , Idoso , Idoso de 80 Anos ou mais , Alaska/epidemiologia , Albuminúria/metabolismo , Índice de Massa Corporal , Doenças Cardiovasculares/metabolismo , Comorbidade , Estudos Transversais , Feminino , Hemoglobinas Glicadas/metabolismo , Humanos , Hipertensão/etnologia , Insulina/sangue , Estilo de Vida , Lipídeos/sangue , Modelos Logísticos , Masculino , Pessoa de Meia-Idade , Obesidade/etnologia , Prevalência , Fatores de Risco , Distribuição por Sexo , Fumar/etnologia , Relação Cintura-Quadril/estatística & dados numéricos
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