Two fatal cases of meningoencephalitis associated with Mycoplasma pneumoniae infection.

Two fatal cases of meningoencephalitis with serological indication of Mycoplasma pneumoniae infection are reported. The patients were young boys, 13 and 17 years old. Attention is drawn to the risk of sequelae or of a fatal outcome in patients where this infection is associated with symptoms from the central nervous system.

Increased lymphocyte ATP-ase activity in patients with carcinomas of the oral cavity and larynx.

Increased mitochondrial ATP-ase activity was found in circulating lymphocytes from 5 out of 8 patients with carcinoma of the oral cavity or oropharynx and from 5 out of 10 patients with carcinoma of the larynx. In a majority of these cases changes in the ATP-ase activity after treatment paralled to the clinical result of treatment. It is suggested that determination of ATP-ase activity of circulating lymphocytes is of diagnostic value in patients with oral, oropharyngeal and laryngeal carcinomas as well as prognostic value after treatment of the patients.

ATP-ase activity of lymphocytes from patients with carcinomas of the urinary bladder.

In 13 out of 26 patients with urinary bladder carcinomas in various stages of malignancy, the ATP-ase activity of circulating lymphocytes was found significantly elevated. A decline in the ATP-ase activity was demonstrated in 14 of 17 patients re-investigated after treatment, while the activity remained unchanged in 2 and rose in 1 patient. No correlation between the clinical tumour stage and the lymphocyte ATP-ase activity was found, but the activity was closely correlated to the histological grade of malignancy. In 11 of the 17 patients the clinical effect of the treatment was closely correlated to a decline in ATP-ase activity. Determination of lymphocyte ATP-ase activity is suggested as an additional and simple help in the diagnosis of bladder carcinoma and in the follow-up control after treatment of patients with this disease.