RESUMO
Three patients with Mycobacterium simiae infection were seen during a 5-yr period. One patient with chronic infiltrative pulmonary disease had the diagnosis established by open lung biopsy. Two patients with normal chest roentgenograms had disseminated infection, one having had elective surgery for a nonfunctioning kidney. Caseating granulomata were discovered in kidney tissue sections. Both M. kansasii and M. simiae were subsequently recovered from bone marrow and urine cultures. The other patient had vertebral osteomyelitis, and M. simiae was isolated from tissue obtained by needle biopsy. To our knowledge, disseminated M. simiae infection has not been previously described.
Assuntos
Infecções por Mycobacterium não Tuberculosas/diagnóstico , Infecções por Mycobacterium/diagnóstico , Mycobacterium/isolamento & purificação , Micobactérias não Tuberculosas/isolamento & purificação , Idoso , Feminino , Humanos , Nefropatias/etiologia , Masculino , Pessoa de Meia-Idade , Osteomielite/etiologia , Tuberculose Pulmonar/etiologiaRESUMO
Mycobacterium kansasii musculoskeletal infections are unusual. The infection presents as either a tenosynovitis, monoarticular arthritis or generalized systemic spread. In 2 patients, vigorous surgical and antimycobacterial medical regimens controlled the infection and produced full return of function.