RESUMO
A case of Gaucher's disease associated with pregnancy is reported. Although clinical symptoms were not present, portal hypertension was detected by ultrasound in the 13th week of pregnancy. Maternal anemia implied the use of erythropoietin from the 33rd week onwards. Good perinatal and maternal outcomes were achieved and there were no hemorrhagic complications.
Assuntos
Doença de Gaucher/diagnóstico , Complicações na Gravidez/diagnóstico , Adulto , Transfusão de Sangue , Cesárea , Terapia Combinada , Eritropoetina/administração & dosagem , Feminino , Doença de Gaucher/terapia , Humanos , Gravidez , Complicações na Gravidez/terapia , Proteínas RecombinantesRESUMO
There are some arguments concerning prenatal Hepatitis B testing: universal screening versus testing of risk groups. A thousand parturients were evaluated in order to assess the sensitivity of risk factors in the identification of Hepatitis B surface antigen (HBsAg) positive women. To achieve that purpose they were questioned regarding risk factors and blood samples were collected for HBsAg testing. Thirty two HBsAg positive parturients were identified. A larger number of HBsAg positive was found amongst women included in the class 5 of the Graffard scale (p = 0.005), or referring contact with patients with hepatitis (p = 0.01). These risk factors identified no more than 17 of the 32 positive mothers (sensitivity = 53%). None of the other risk factors proved significant. The entire questionnaire allows a sensitivity of 87.5% but presents a specificity of 22.5%. In this population, risk factors are not a good method of screening HBsAg positive women. A universal screening must be undertaken in order to prevent vertical transmission of the virus and to detect families in risk.
