RESUMO
The paper presents the results of anterior spine fusion in 250 patients with tuberculous spondylitis involving 2 to 8 vertebrae, by using free and non-free autologous bone grafts, carbonaceous implants, and revascularized transplants. Anterior spine fusion added to posterior spinal fixation with a CD-type metal construction. A tuberculous process in the spine was cured in 96.1% of cases; the spinal support capability recovery rate was 95.2% in the early postoperative period and in 93.5% in the late one.
Assuntos
Mycobacterium tuberculosis/patogenicidade , Recuperação de Função Fisiológica , Coluna Vertebral/microbiologia , Coluna Vertebral/cirurgia , Espondilite/microbiologia , Espondilite/cirurgia , Adolescente , Adulto , Idoso , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Radiografia , Costelas/transplante , Fusão Vertebral/instrumentação , Coluna Vertebral/diagnóstico por imagem , Espondilite/diagnóstico por imagem , Transplante Autólogo , Resultado do TratamentoAssuntos
Histiocitose de Células de Langerhans/diagnóstico , Tuberculose/diagnóstico , Adulto , Osso e Ossos/diagnóstico por imagem , Diagnóstico Diferencial , Erros de Diagnóstico , Fêmur/diagnóstico por imagem , Fluoroscopia , Histiocitose de Células de Langerhans/diagnóstico por imagem , Humanos , Vértebras Lombares , Masculino , Radiografia Torácica , Tomografia Computadorizada por Raios X , Tuberculose/diagnóstico por imagem , Tuberculose Pulmonar/diagnóstico , Tuberculose Pulmonar/diagnóstico por imagem , Tuberculose da Coluna Vertebral/diagnóstico , Tuberculose da Coluna Vertebral/diagnóstico por imagemRESUMO
The post mortem content and composition of cerebrosides, sulfocerebrosides and gangliosides found in different sections of the spinal marrow of the healthy persons and 5 patients with spinal tuberculosis were analysed. It was shown that the changes in the content of gangliosides were varying in the lesion focus of different patients. In all patients with chronic tuberculous spondylitis, a significant drop in the content of cerebrosides (myelin markers) and sulfocerebrosides in the lesion focus, as compared with controls, was detected. There were some changes found in the content of cerebrosides and gangliosides in the spinal marrow lesion focus, which are also typical of the disease associated with demyelination of the nervous system. The findings suggest that identification of blood anti-cerebroside antibodies in patients with spinal tuberculosis allows one to make an early diagnosis of abnormalities in the cellular structures of nervous tissue in this form of the disease and to predict its course.
Assuntos
Cerebrosídeos/metabolismo , Gangliosídeos/metabolismo , Medula Espinal/metabolismo , Tuberculose da Coluna Vertebral/metabolismo , Cerebrosídeos/química , Cerebrosídeos/deficiência , Vértebras Cervicais/metabolismo , Gangliosídeos/química , Gangliosídeos/deficiência , Humanos , Vértebras Lombares/metabolismo , Pessoa de Meia-Idade , Medula Espinal/química , Vértebras Torácicas/metabolismoRESUMO
Content and composition of phospholipids in various sections of the spinal marrow were investigated in patients with spinal tuberculosis. In the patients with tuberculous spondylitis, changes in the content of phospholipids in the spinal marrow were observed which were especially pronounced in the injured areas. The changes varied in different patients: in some patients, the content of the lipids was changed insignificantly while in the others it was markedly lowered (5-6-fold). Investigation of the phospholipid composition revealed in some patients decreased relative contents of the phosphatidyl ethanolamine plasmogenic form characteristic of myelin. It was suggested that the spinal marrow cells had undergone destruction in the injured areas.
