RESUMO
Hyponatremia due to isolated adrenocorticotropic hormone (ACTH) deficiency is difficult to diagnose as it is usually indistinguishable from non-endocrine syndrome of inappropriate antidiuretic hormone secretion (SIADH). We present a case secondary to empty sella. Most patients with empty sella remain asymptomatic throughout life and require no treatment; however, in cases involving the development of isolated ACTH deficiency, corticosteroid treatment should be enforced to avoid fatal consequences.
Assuntos
Hormônio Adrenocorticotrópico/deficiência , Síndrome da Sela Vazia/complicações , Doenças do Sistema Endócrino/etiologia , Doenças Genéticas Inatas/etiologia , Hipoglicemia/etiologia , Síndrome de Secreção Inadequada de HAD/etiologia , Sódio/sangue , Hormônio Adrenocorticotrópico/sangue , Idoso , Síndrome da Sela Vazia/diagnóstico , Doenças do Sistema Endócrino/sangue , Doenças do Sistema Endócrino/diagnóstico , Doenças Genéticas Inatas/sangue , Doenças Genéticas Inatas/diagnóstico , Humanos , Hipoglicemia/sangue , Hipoglicemia/diagnóstico , Síndrome de Secreção Inadequada de HAD/sangue , Síndrome de Secreção Inadequada de HAD/diagnóstico , Imageamento por Ressonância Magnética , MasculinoRESUMO
Sarcomas represent a challenge t clinicians as they are rare and diagnosis is often delayed. Soft tissue sarcomas are relatively uncommon cancers, the incidence is estimated about 1% from all malignant tumors. Due to aggressive biological behavior of pleomorphic undifferentiated sarcoma diagnosis must hi made as quickly as possible. MRI is the standard imaging modality for investigating possibl3 malignant masses. Excisional biopsy appears to be necessary for differentiating soft tissus sarcoma from expanding hematoma. FDG PET scans may be helpful in specific circum. stances (as was the situation in our case, because the lesion is composed from two components: an area without precise edges and a necrotic-cystic area).