Influence of prenatal corticosteroid therapy on neonatal vitality and utility as a labor-inducing agent in Santa Inês ewes.

Since the 1970s, maternal corticosteroid therapy has been used successfully to induce labor. This allows for better monitoring of parturients and provision of first aid to neonates, improving neonatal viability, as this treatment induces maturation in a variety of fetal tissues, thereby reducing morbidity and mortality. Although the effects of corticosteroids are well known, few studies have investigated the influence of this therapy in Santa Inês sheep. This study aimed to evaluate the efficacy of dexamethasone at two doses (8 and 16 mg) to induce lambing in Santa Inês ewes at 145 days of gestation and assess its effects on neonatal vitality. For this study, 58 ewes raised in an extensive system were investigated. Pregnancy was confirmed after artificial insemination at a set time or after controlled mounting. Ewes were separated into three groups: an untreated control group (G1: 0 mg) and groups treated with two doses of dexamethasone (G2: 8 mg and G3: 16 mg). In total, 79 lambs were born. Their vitality was assessed based on their Apgar score, weight, temperature, and postnatal behavior. SAS v9.1.3 (SAS Institute, Cary, NC) was used to analyze data, considering a 5% significance level for all analyses. The births in the induced groups occurred 48.4 ± 22.1 h after induction, while the ewes that underwent non-induced labor gave birth 131.96 ± 41.9 h after placebo application (p < 0.05), confirming the efficacy of dexamethasone to induce and synchronize labor. The induced and non-induced neonates had similar Apgar scores, temperatures, weights, and postnatal behavioral parameters (p > 0.05). This study showed that inducing labor in Santa Inês ewes at 145 days of gestation with a full (16 mg) or half dose (8 mg) of dexamethasone is an effective technique and does not compromise neonate vitality.

The complete mitochondrial genome of Leucoptera coffeella (Lepidoptera: Lyonetiidae) and phylogenetic relationships within the Yponomeutoidea superfamily.

The coffee leaf miner (Leucoptera coffeella) is one of the major pests of coffee crops in the neotropical regions, and causes major economic losses. Few molecular data are available to identify this pest and advances in the knowledge of the genome of L. coffeella will contribute to improving pest identification and also clarify taxonomy of this microlepidoptera. L. coffeella DNA was extracted and sequenced using PacBio HiFi technology. Here we report the complete L. coffeella circular mitochondrial genome (16,407 bp) assembled using Aladin software. We found a total of 37 genes, including 13 protein-coding genes (PCGs), 22 transfer RNA genes (tRNAs), 2 ribosomal RNA genes (rRNAs) and an A + T rich-region and a D-loop. The L. coffeella mitochondrial gene organization is highly conserved with similarities to lepidopteran mitochondrial gene rearrangements (trnM-trnI-trnQ). We concatenated the 13 PCG to construct a phylogenetic tree and inferred the relationship between L. coffeella and other lepidopteran species. L. coffeella is found in the Lyonetiidae clade together with L. malifoliella and Lyonetia clerkella, both leaf miners. Interestingly, this clade is assigned in the Yponomeutoidea superfamily together with Gracillariidae, and both superfamilies displayed species with leaf-mining feeding habits.

Does GnRH treatment at TAI regardless of estrus occurrence increase pregnancy rate in crossbred Bos taurus suckled cows?

The impact of GnRH treatment on the day of TAI in beef cows has received limited investigation, especially concerning its association with estrus expression. Consequently, two experiments were conducted to assess the potential of GnRH treatment on the day of TAI to enhance fertility according to the expression or not of estrus in beef cows. Experiment 1 aimed to determine ovulation rate and luteal function, while Experiment 2 aimed to determine the effect of the two GnRH treatment approaches on pregnancy rate. In Experiment 1, multiparous Brangus suckling cows (n = 17) were submitted to an 8-day TAI protocol. Estrus occurrence was evaluated based on chalk removal on D10 (TAI) and cows were assigned to receive GnRH (25µg lecirelin; im) according to the group: GnRH (n = 7), regardless of estrus expression; or selectGnRH (n = 10), only cows not detected in estrus. Ovulation rate occurring until 77h after IVD removal did not differ (p = 0.17) between GnRH (85.7%; 6/7) and selectGnRH (100%; 10/10). Also, corpus luteum size and serum progesterone concentration were not affected (p>0.05) by treatments. In Experiment 2, crossbred taurine suckled cows (n = 384) were submitted to the same protocol as described in Experiment 1 and were randomly allocated to GnRH or selectGnRH groups. There was no difference in P/AI between groups (selectGnRH = 55.6%; GnRH = 54.3%; p = 0.7) 30 days after TAI. As expected, there was a pronounced effect (p<0.0001) of estrus expression on P/AI (Estrus = 61.5%; No estrus = 33.0%), regardless of group. In summary, ovulation timing and rate and luteal function did not differ between groups. Also, GnRH administration only in cows that do not show estrus is recommended, considering hormone savings and similar conception rate.

Effects of two oral electrolyte solutions in healthy newborn lambs.

This study aimed to evaluate the effects of two oral electrolyte solutions (OES), commercialized for the hydration of calves, on the water, electrolyte, and acid-base balance of newborn lambs. Twenty healthy crossbred Santa Inês lambs, 10 days old, 4-5 kg of body weight (BW), and fed on mother's milk, were included. The OES tested were slightly hyposmolar (OES 1: 279 mOsm/L; and OES 2: 283 mOsm/L) and had an alkalizing potential with an effective strong ion difference (SID3) of 76 mmol/L (OES 1) and 58 mmol/L (OES 2). In a crossover design, all lambs received the two OES, one at a time, with an interval of 7 days. On the day of treatment, the lambs received a volume corresponding to 5% of BW administered by esophageal tube at 0 and 6 h. Physical examinations were performed and venous blood samples were taken at 0, 6, 12, 24, and 48 h. Packed cell volume, total plasma protein, pH, partial pressure of carbon dioxide, bicarbonate ion, base excess, sodium (Na+), potassium, chloride (Cl-), SID3, L-lactate, glucose, anion gap, total concentration of non-volatile weak acids, and percentage change in plasma volume were measured. Data were analyzed by two-way repeated measures ANOVA. OES caused iatrogenic imbalances characterized by expansion of plasma volume, change in the Na+ and Cl- ratio with increase in plasma SID3, and strong ion metabolic alkalosis. These imbalances were mostly reversed 24 h after the start of treatment and did not differ (P > 0.05) between the two tested OES. The absence of side effects indicates that the tested commercial OES are safe for use in newborn lambs. Further studies are needed to prove the therapeutic efficacy of these OES in dehydrated sick lambs with metabolic acidosis.

3D-printed and conventional provisional single crown fabrication on anterior implants: A randomized clinical trial.

OBJECTIVES: The present study aims to compare provisional single crowns on anterior implants made using conventional PMMA and 3D-printed workflows. The study assessed the occurrence of failures, color variation, signs of early deterioration, operating time, and patients' satisfaction with the treatment through a randomized controlled trial. METHODS: This study was conducted as a randomized controlled trial, following the SPIRIT and CONSORT guidelines. Patients were included in the study after meeting the eligibility criteria and were randomly assigned to one of two groups (conventional and 3D-printed). FDI criteria, visible plaque index (VPI), bleeding on probing (BOP), and color variation were considered as the primary outcomes. Operating time and patient satisfaction were also assessed as secondary outcomes. Fisher's exact test was performed to analyze the association between the primary and secondary outcomes and the study groups. Mann-Whitney test was used to compare the mean VAS satisfaction scores between the conventional PMMA and 3D-printed groups (STATA 14™, with an α = 0.05). RESULTS: A total of 42 provisional single crowns (n = 21) were made for 33 patients. Only the fracture parameter (FDI) showed a statistically significant difference, with 3D-printed provisionals exhibiting higher rates of catastrophic failures compared to conventional ones (p = 0.05). Although the operating time for the 3D-printed group was shorter (p < 0.001), no statistical difference observed in patients' satisfaction regarding esthetics, phonetics, chewing, or comfort. SIGNIFICANCE: 3D-printed and conventional PMMA provisional single crowns showed comparable clinical performance, except for the observed fracture types. Although 3D-printed provisional restorations showed a shorter operating time, overall patients' satisfaction was not affected.

Single-step genome-wide association studies and post-GWAS analyses for the number of oocytes and embryos in Gir cattle.

Genome-Wide Association Studies (GWAS) are used for identification of quantitate trait loci (QTL) and genes associated with several traits. We aimed to identify genomic regions, genes, and biological processes associated with number of total and viable oocytes, and number of embryos in Gir dairy cattle. A dataset with 17,526 follicular aspirations, including the following traits: number of viable oocytes (VO), number of total oocytes (TO), and number of embryos (EMBR) from 1641 Gir donors was provided by five different stock farms. A genotype file with 2093 animals and 395,524 SNP markers was used to perform a single-step GWAS analysis for each trait. The top 10 windows with the highest percentage of additive genetic variance explained by 100 adjacent SNPs were selected. The genomic regions identified in our work were overlapped with QTLs from QTL database on chromosomes 1, 2, 5, 6, 7, 8, 9, 13, 17, 18, 20, 21, 22, 24, and 29. These QTLs were classified as External, Health, Meat and carcass, Production or Reproduction traits, and about 38% were related to Reproduction. In total, 117 genes were identified, of which 111 were protein-coding genes. Exclusively associations were observed for 42 genes with EMBR, and 1 with TO. Also, 42 genes were in common between VO and TO, 28 between VO and EMBR, and four genes were in common among all traits. In conclusion, great part of the identified genes plays a functional role in initial embryo development or general cell functions. The protein-coding genes ARNT, EGR1, HIF1A, AHR, and PAX2 are good markers for the production of oocytes and embryos in Gir cattle.

Enteral hydration in cows: Comparison between continuous flow and bolus administration.

BACKGROUND: Enteral hydration in cattle is most commonly performed as a bolus (B) via the ororuminal route, although continuous flow (CF) administration via the nasoesophageal route represents a viable alternative. Currently, no study has compared the effectiveness of these two methods. This study aimed to compare the efficiency of enteral hydration using CF and B to correct water, electrolyte and acid-base imbalances in cows. METHODS: Protocols for the induction of dehydration were applied twice to eight healthy cows, with an interval of 1 week. In a crossover design, two types of enteral hydration were performed using the same electrolyte solution and volume equal to 12% of bodyweight (BW): CF (10 mL/kg/h, between 0 and 12 hours) and B (6% BW, twice, at 0 and 6 hours). Clinical and blood variables were determined at -24, 0, 6, 12 and 24 hours and compared using repeated-measures ANOVA. RESULTS: Induced moderate dehydration and hypochloremic metabolic alkalosis were corrected after 12 hours using the two hydration methods, with no differences observed between the methods. LIMITATIONS: The study was conducted with induced rather than natural imbalances, so the findings should be interpreted cautiously. CONCLUSION: Enteral CF hydration is as effective as B hydration in reversing dehydration and correcting electrolyte and acid-base imbalances.

Endodontic therapy in patients with inherited bleeding disorders: a scoping review.

This systematic scoping review aimed to map available evidence regarding endodontic therapy in patients with inherited bleeding disorders (IBDs). Studies in medicine or dentistry were selected if they reported on endodontic therapy in individuals with IBDs such as hemophilia A, hemophilia B, or von Willebrand disease. Two independent researchers performed searches and screening in PubMed/MEDLINE, Embase, Scopus, Web of Science, and Cochrane Library. The search initially yielded 676 potentially relevant studies, 14 of which were included in the final analysis. Of these 14 studies, 3 were classified as consensus statements or guidelines, 3 as observational studies, 2 as reviews, 5 as case reports, and 1 as an editorial. Most of the evidence regarding prophylactic treatment (eg, blood transfusion, replacement therapy, or medication administration) prior to endodontic therapy was derived from observational studies. The most frequently reported procedure was endodontic therapy, while 1 case report described a surgical endodontic procedure. Most studies included in the analysis reported that these procedures could be performed under local anesthesia. Two case reports and 1 observational study described complications after endodontic therapy in patients with IBDs. This scoping review revealed a lack of well-designed studies related to the topic of endodontic therapy in patients with IBDs. The available evidence suggests that endodontic therapy in patients with IBDs can be considered a low-risk procedure; local anesthesia should be used in most cases when patients with IBDs are treated, but the use of prophylactic measures is preferred when nerve block anesthesia is required; endodontic therapy can be conducted in a clinical setting without the need for hospital admittance; and, although the number of reported complications is small, the risk should not be ignored.

Reporting quality of scoping reviews in dental public health.

BACKGROUND: The study aimed to explore reporting characteristics of scoping reviews in dental public health and the impact of some factors on the reporting quality. METHODS: This study searched for dental public health scoping reviews in PubMed and Scopus without year restrictions and restricted to English-language publications. Study selection was undertaken by two reviewers independently. One reviewer, after training, extracted data from included studies considering general study characteristics and reporting characteristics. The impact of PRISMA-ScR publication, journal endorsement, and use of study protocol on the reporting was explored. RESULTS: Eighty-one scoping reviews were included. Five items presented rates of appropriate reporting higher than 80% considering the overall percentage. Related to the impact of PRISMA-ScR publication, six items were found more often in scoping reviews published after the publication of PRISMA-ScR than in scoping reviews published before the publication of PRISMA-ScR. With regards to journals endorsement, only two reporting characteristics were found more often in scoping reviews published in journals that endorse the PRISMA-ScR statement than in scoping reviews published in non-endorsers journals. Last, regarding the use of the pre-specified protocol, five reporting characteristics presented differences in studies reporting the use of pre-specified protocol than in studies that did not mention the use of a protocol. All differences were statistically significant. CONCLUSIONS: Important information is missing in the included scoping reviews demonstrating crucial reporting problems.

Pedigree reconstruction and population structure using SNP markers in Gir cattle.

Our objective was to establish a SNPs panel for pedigree reconstruction using microarrays of different densities and evaluate the genomic relationship coefficient of the inferred pedigree, in addition to analyzing the population structure based on genomic analyses in Gir cattle. For parentage analysis and genomic relationship, 16,205 genotyped Gir animals (14,458 females and 1747 males) and 1810 common markers to the four SNP microarrays were used. For population structure analyses, including linkage disequilibrium, effective population size, and runs of homozygosity (ROH), genotypes from 21,656 animals were imputed. Likelihood ratio (LR) approach was used to reconstruct the pedigree, deepening the pedigree and showing it is well established in terms of recent information. Coefficients for each relationship category of the inferred pedigree were adequate. Linkage disequilibrium showed rapid decay. We detected a decrease in the effective population size over the last 50 generations, with the average generation interval around 9.08 years. Higher ROH-based inbreeding coefficient in a class of short ROH segments, with moderate to high values, was also detected, suggesting bottlenecks in the Gir genome. Breeding strategies to minimize inbreeding and avoid massive use of few proven sires with high genetic value are suggested to maintain genetic variability in future generations. In addition, we recommend reducing the generation interval to maximize genetic progress and increase effective population size.

A Modified Technique for Induced Gingival Growth Around Compromised Teeth Prior to Implant Placement: A Report of Two Cases.

Regenerative and reconstructive periodontal plastic surgery are important options for treating marginal tissue recession and can be indicated for root coverage or periodontal procedures prior to implant placement. Among the available procedures, periodontal flaps with subepithelial connective tissue graft (CTG) is the most common treatment option to achieve proper tissue manipulation. The present study proposes a modification of a previous technique for inducing spontaneous gingival growth around teeth that will be extracted prior to implant placement, through successive reduction of the buccal root surface. This successive reduction of root surfaces is performed with diamond burs, and such reductions create space for the gingival tissue to grow coronally by reducing root convexity and, consequently, stimulating the healing process with the formation of granulation tissue that will then differentiate into keratinized tissue. The presented technique is suggested to improve the esthetic outcomes for cases involving tooth extraction, implant placement in the extraction socket, and immediate loading with interim restoration and CTG.

Assessment of Surgical and Radiographic Parameters for Abutment Height Selection: A Prospective Study with 1-Year Follow-up.

PURPOSE: The "one-abutment, one-time" concept entails the placement of a definitive abutment at the time of implant placement, without removal during prosthesis manufacture, with the aim to promote a safer environment for the peri-implant tissues. Identifying surgical and radiographic parameters that can assist with the abutment height selection would facilitate the adoption of the one-abutment, one-time concept. Therefore, the aim of this study was to assess the role of surgical and radiographic parameters as predictive factors for abutment height selection in implant-retained single crowns. MATERIALS AND METHODS: This prospective study assessed the role of surgical and radiographic measurements in the implant survival and success rates and marginal bone loss in implant-retained single crowns. Implants were placed in both healed sites and extraction sockets, and the distances between the implant platform and alveolar bone crest, implant platform and gingival margin, and buccal gap (when present) were recorded using a straight periodontal probe. Digital radiographs were made at implant placement (T0), abutment height selection (Ta), and 1-year follow-up (Tf), and the distance between the implant platform and the alveolar bone crest (mm) was assessed. Linear regression models and Pearson correlation were used to assess the influence of primary and secondary outcomes on abutment height. RESULTS: A total of 130 implants were placed in 68 patients. The mean surgical distance between the bone crest and the implant platform was 1.71 ± 1.01 mm, and the mean distance from the gingival margin to the implant platform was 3.94 ± 1.90 mm, while at the abutment selection appointment, the mean transmucosal height was 3.58 ± 1.50 mm. A high linear correlation was found between the selected abutment height and two primary outcomes: the radiographic implant platform to alveolar bone crest distance at T0 (r2 = 0.66; P < .001) and the transmucosal height at Ta (r2 = 0.81; P < .001). CONCLUSION: Radiographic measurements of the distance between the implant platform and the alveolar bone crest at implant placement can serve as an important parameter to select the abutment height for definitive restorations.

COVID-19 cross-sectional study in Maricá, Brazil: The impact of vaccination coverage on viral incidence.

Population surveillance in COVID-19 Pandemic is crucial to follow up the pace of disease and its related immunological status. Here we present a cross-sectional study done in Maricá, a seaside town close to the city of Rio de Janeiro, Brazil. Three rounds of study sampling, enrolling a total of 1134 subjects, were performed during May to August 2021. Here we show that the number of individuals carrying detectable IgG antibodies and the neutralizing antibody (NAb) levels were greater in vaccinated groups compared to unvaccinated ones, highlighting the importance of vaccination to attain noticeable levels of populational immunity against SARS-CoV-2. Moreover, we found a decreased incidence of COVID-19 throughout the study, clearly correlated with the level of vaccinated individuals as well as the proportion of individuals with detectable levels of IgG anti-SARS-CoV-2 and NAb. The observed drop occurred even during the introduction of the Delta variant in Maricá, what suggests that the vaccination slowed down the widespread transmission of this variant. Overall, our data clearly support the use of vaccines to drop the incidence associated to SARS-CoV-2.

Insecticides in Use and Risk of Control Failure of Boll Weevil (Coleoptera: Curculionidae) in the Brazilian Cerrado.

Growers rely on synthetic insecticides to control the boll weevil throughout the reproductive cotton stage. An average of 19.6 insecticide applications (range: 10 to 30) for control of boll weevil were found in a survey with growers in the Brazilian Cerrado, covering an area of 494,100 hectares of cotton. Twenty-one insecticides were applied, with 64.8% of the applications made with malathion, fipronil, carbosulfan, and thiamethoxam + lambda-cyhalothrin. These four insecticides were used by 100, 76, 70, and 62% of the growers, with respectively 7.2, 2.1, 1.8, and 1.6 applications. Growers classified their boll weevil control achieved into four categories (fair, good, very good, or excellent), without correlation between these categories with the number of insecticide applications. Control of cotton regrowth and volunteer cotton plants were the major obstacles for effective boll weevil management, followed by the low efficacy of insecticides. Five registered insecticides to spray cotton against other pests than boll weevil were enlisted by growers with potential for recommendation. A boll weevil standard population for susceptibility was assayed with 27 insecticides and the results presented within a failure risk quotient (FRQ). The FRQ of eight, six, and 13 of the 27 tested insecticides was high, intermediate, and low, respectively. The high FRQ included 7 of 10 pyrethroid formulations, pymetrozine, and methomyl. On the opposite end, fipronil had the lowest FRQ value.

The effects of thiamethoxam on coffee seedling morphophysiology and Neotropical leaf miner (Leucoptera coffeella) infestations.

BACKGROUND: Coffee (Coffea arabica L.) is one of the main commodities produced in Brazil. Insecticides like the (systemic) neonicotinoid thiamethoxam are widely used to suppress pest populations during coffee production, in particular the Neotropical leaf miner (Leucoptera coffeella Guérin-Mèneville & Perrottet, 1842) (Lepidoptera: Lyonetiidae). In addition to its efficacy against this pest species, thiamethoxam is also thought to be a bioactivator of plant metabolism, but has not yet been tested for such activity. Thus, the objectives of the present study were (1) to assess the concentration-response effects of thiamethoxam on the vegetative vigor of coffee seedlings (C. arabica 'Catuaí 144' cultivar) at different concentrations [2, 20, 40, 80 and 200 mg active ingredient (a.i.) kg-1 ] applied via soil drenching and (2) to evaluate if the plant response interferes with the effectiveness of thiamethoxam in controlling leaf miner populations. The morphophysiological traits of the coffee seedlings were evaluated 20, 40, 60 and 80 days after application, and leaf miner infestations were recorded starting 20 days after the insecticide application with the releasing of adults, and every 20 days afterwards. RESULTS: The results indicated that thiamethoxam has a deleterious effect on the morphophysiological traits of the plants compromising their development with increase in concentrations. However, leaf area exhibited a different pattern with a peak at 50 mg a.i. kg-1 consistent with thiamethoxam-induced hormesis (i.e. biphasic response with stimulatory effect at sublethal range of a toxic substance at the higher concentration). Nonetheless, such bioactivator effect did not affect thiamethoxan effectiveness against the leaf miner even at the lowest concentration tested. CONCLUSION: Thiamethoxan exhibited bioactivation effect on leaf at low concentration, but without compromising efficacy against leaf miner populations. Therefore, its proposed metabolism-boosting properties may encourage the unnecessary use of this insecticide, potentially leading to higher selection for insecticide resistance and an eventual decline in its effectiveness against the Neotropical leaf miner. © 2022 Society of Chemical Industry.

Can anti-PGL-I antibody isotypes differentiate leprosy contacts and leprosy patients?

BACKGROUND: Serological tests for antibody measurement in leprosy have a series of limitations in discriminating contacts and patients. The present paper intends to evaluate if association of more than one antibody isotype in serum samples may be a useful tool in leprosy diagnosis. METHODS: This study evaluated 395 leprosy contacts and 71 leprosy index cases living in endemic municipalities in Northeastern Brazil. The participants were evaluated according to their anti-phenolic glycolipid antigen-I isotype (PGL-I) profile. Serum anti-PGL-I IgM, IgG, and IgA were measured by indirect ELISA. RESULTS: A strong association was found for antibody positivity in MB leprosy index cases. The odds ratios were 6.11 (95% CI 3.08 - 12.16) for IgM, 3.31 (1.66 - 6.61) for IgG, and 16.97 (8.39 - 34.2) for IgA. For IgM associated with one or more isotypes, the OR was 21.0 (95% CI 10.11 - 43.64), and for IgG + IgA, the OR was 17.58 (6.23 - 49.54). The highest diagnostic sensitivity of 76.0% (95% CI 61.8 - 86.9) was observed for IgM, and the lowest value was 24.1% (13.0 - 38.2), which was observed for IgG + IgA isotypes. Regarding presumptive positive predictive values, the lowest value was obtained for IgM at 24.7% (95% CI 18.1 - 32.3), and the highest values were observed for IgM+ one or more isotypes and for IgG + IgA isotype at 60.0% (44.3 - 74.3) and 66.7% (41.0 - 86.7), respectively. CONCLUSIONS: The present work demonstrated that by associating two or more positive antibody isotypes, the risk of facing a real case of leprosy may increase.

Comparison of material properties and biofilm formation in interim single crowns obtained by 3D printing and conventional methods.

STATEMENT OF PROBLEM: Three-dimensionally printed interim restorations are among the recent technological advancements in dentistry. However, evidence of their performance is lacking. PURPOSE: The purpose of this in vitro study was to compare the properties of interim restorations made by 3D printing with different technologies, laser stereolithography (SLA), technology and selective laser sintering (SLS) with those obtained by conventional techniques from acrylic resin and bis-acryl resin. MATERIAL AND METHODS: Four different groups (acrylic resin, bis-acryl resin, SLS, SLA) were tested for flexural strength, Vickers microhardness, fatigue test, compressive strength, surface roughness before and after polishing, and biofilm formation. Specimens were made in the form of rectangular blocks, disks, and single crowns by following the manufacturing technique of each material. One-way ANOVA was used to test biofilm formation, Vickers microhardness, and the results of the 3-point bend flexural test, while the paired t test was used to assess differences in surface roughness between the materials (α=.05 for all tests). RESULTS: The highest Vickers microhardness value was for acrylic resin interim crowns, while the elastic moduli were lower for both the 3D printed materials. Only the SLA resin fractured during the fatigue test. For surface roughness, a statistically significant difference was found among the studied materials (P<.001), with SLA resin and bis-acryl resin having the lowest values. No statistically significant differences were found for biofilm formation (P>.05). CONCLUSIONS: SLS resin had favorable results for the Vickers microhardness, higher maximum flexural strength, and peak stress in load-to-fracture tests, the fatigue test, and biofilm formation compared with acrylic resin and bis-acryl resin, while SLA resin showed favorable results only for biofilm formation and surface roughness.

Delayed Bleeding in a Hemophilic Patient After Sinus Floor Elevation and Multiple Implant Placements: A Case Report.

Dental treatments in hemophilic patients are challenging, and the absence of adequate preparation for the procedures can be life-threatening. This letter describes a delayed postoperative bleeding after multiple dental implants with sinus floor elevation in a patient with mild hemophilia A.

Anderson localization induced by interaction in linearly coupled binary Bose-Einstein condensates.

In this paper we investigate the existence of Anderson localization induced by one specific component of a binary Bose-Einstein condensate (BEC). We use a mean-field approach, in which each type of particle of the BEC is considered as a specific field, and we consider that only one kind of particle is subject to a quasiperiodic potential, which induces a localization in the partner field. We assume the system is under a Rabi coupling, i.e., a linear coupling mixing the two-field component, and we investigate the conditions associated with the parameter values of the system for observing the localization. Numerical simulations are performed, confirming the existence of Anderson localization in the partner field.

Influence of low-level laser therapy on implant stability in implants placed in healed sites: a randomized controlled trial.

BACKGROUND: The present study aims to assess the influence of low-level laser therapy (LLLT) on stability in implants placed in healed sites. MATERIAL AND METHODS: The present study followed the SPIRIT statement and is reported according to CONSORT. Patients were randomly allocated to LLLT or control groups. LLLT consisted in the application of 808-nm GaAlA laser applied before the preparation of the implant bed and after suturing (80 seconds; 11J/cm2). Implant stability quotient (ISQ) and the distance between the implant platform to the alveolar bone crest (millimeters) were assessed at implant placement (T0) and the abutment selection phase (4-6 months, Ta). RESULTS: A total of 64 implants were placed in 33 patients. The insertion torque ranged from 10 to 70 N.cm (mean 43.23; SD ±16.82). The T0 ISQ ranged from 18 to 95.5 (mean 61.7; SD ±18.23) and the crestal bone radiographic distance was 2.03 mm (SD±1.27). At Ta, the ISQ ranged from 39 to 90 (mean 64.2; SD±9.84), and the mean crestal bone radiographic loss was 1.70mm (SD±1.65). However, no differences were observed when LLLT and control groups were compared with ISQ difference (Ta-T0; p=0.598) or radiographical peri-implant alterations (p=0.531). CONCLUSION: LLLT did not influence the implant stability in implants placed in healed sites compared to a control group. TRIAL REGISTRATION: ReBEC, RBR-35TNJ7 . Registered May 23, 2018.