RESUMO
Survival of older patients with acute nonlymphocytic leukemia treated with chemotherapy was compared with those given only supportive care. The treated group was younger and had better survival. The benefits which measure in months must be balanced against socioeconomic cost, toxicity of therapy, patient wishes, and evolving information about the standards of management in the older leukemia patient.
Assuntos
Protocolos de Quimioterapia Combinada Antineoplásica/uso terapêutico , Leucemia Mieloide/tratamento farmacológico , Leucemia Mieloide/mortalidade , Doença Aguda , Fatores Etários , Idoso , Idoso de 80 Anos ou mais , Citarabina/administração & dosagem , Daunorrubicina/administração & dosagem , Doxorrubicina/administração & dosagem , Feminino , Humanos , Idarubicina/administração & dosagem , Masculino , Pessoa de Meia-Idade , Indução de Remissão , Fatores Sexuais , Taxa de Sobrevida , Tioguanina/administração & dosagemRESUMO
We review a ten-year experience in treating 60 patients with multiple myeloma. Infectious episodes occurred in 33 patients. Urinary tract infections caused by gram-negative organisms were the most frequent infections, and most of these were the result of catheterization. Pneumonia due to Streptococcus pneumoniae was encountered infrequently. This series confirms the emergence of gram-negative bacilli as the predominant pathogens in patients with multiple myeloma, and emphasizes the risk of instrumentation in these patients.
Assuntos
Infecções Bacterianas/complicações , Mieloma Múltiplo/complicações , Adulto , Idoso , Idoso de 80 Anos ou mais , Infecções Bacterianas/epidemiologia , Infecções Bacterianas/microbiologia , Infecção Hospitalar/complicações , Infecção Hospitalar/epidemiologia , Humanos , Masculino , Pessoa de Meia-Idade , Mieloma Múltiplo/mortalidadeRESUMO
Perinephric abscess is an uncommon complication of acute pyelonephritis. A nephrobronchial colonic fistula is a rare sequela of perinephric abscesses. We report such a case, review the literature, and discuss the associated morbidity and diagnostic dilemmas.