RESUMO
The small cells lung carcinoma (SCLC) represents 10-25% of the bronchogenical carcinomas, prevails at middle ages and is closely associated with tobacco smoke. It belongs to the group of carcinomas with neuroendocrine differentiation, the patients presenting various paraneoplastic syndromes. The study was performed on 491 patients with a clinical and radiological suspicion of bronchopulmonary cancer. In this study, the histopathological examination gives results similar to those mentioned in the medical literature for the small cells lung carcinoma, prevailing in the case of young patients. The immunohistochemical examinations are particularly precious in confirming the diagnosis, especially in the diagnosis of the lymphonodular micrometastases.
Assuntos
Carcinoma de Células Pequenas/diagnóstico , Neoplasias Pulmonares/diagnóstico , Adulto , Idoso , Idoso de 80 Anos ou mais , Broncoscopia , Carcinoma de Células Pequenas/patologia , Carcinoma de Células Pequenas/secundário , Carcinoma de Células Escamosas/diagnóstico , Carcinoma de Células Escamosas/metabolismo , Carcinoma de Células Escamosas/patologia , Cromograninas/metabolismo , Feminino , Humanos , Imuno-Histoquímica , Neoplasias Pulmonares/metabolismo , Neoplasias Pulmonares/patologia , Metástase Linfática , Masculino , Pessoa de Meia-Idade , FumarRESUMO
Acute effects of l-carnitine (vials of 1 g endovenous) were recorded in a group of elite athletes (17 swimmers) by a prospective double-blind placebo-controlled trial and cross over. Significant changes were registered after l-carnitine injection, compared to placebo, for FFA, triglycerides, lactic acid after exercise, evoked muscular potential, 90 to 120 minutes after injection. The authors explain these changes by the increase of free carnitine, which permits a larger quantity of FFA to enter the mitochondria and to be more extensively used as energy source.
