RESUMO
A 68-year-old woman had uneventful deep sclerectomy with a collagen implant in the left eye that was complicated by infectious keratitis 2 weeks later. Corneal scraping revealed the presence of Staphylococcus aureus. The patient responded to topical antibiotic treatment, and the corneal infiltration resolved, leaving a corneal scar. Bacterial keratitis may occur after nonpenetrating glaucoma surgery and should be included in the list of early postoperative complications.
Assuntos
Úlcera da Córnea/microbiologia , Infecções Oculares Bacterianas/microbiologia , Glaucoma de Ângulo Aberto/cirurgia , Complicações Pós-Operatórias , Infecções Estafilocócicas/microbiologia , Idoso , Antibacterianos/uso terapêutico , Colágeno/administração & dosagem , Córnea/microbiologia , Úlcera da Córnea/diagnóstico , Úlcera da Córnea/tratamento farmacológico , Quimioterapia Combinada , Infecções Oculares Bacterianas/diagnóstico , Infecções Oculares Bacterianas/tratamento farmacológico , Feminino , Fluormetolona/uso terapêutico , Gentamicinas/uso terapêutico , Humanos , Testes de Sensibilidade Microbiana , Esclerostomia , Infecções Estafilocócicas/diagnóstico , Infecções Estafilocócicas/tratamento farmacológico , Staphylococcus aureus/isolamento & purificaçãoRESUMO
PURPOSE: The exact anatomic and neurophysiologic correlates of idiopathic generalized epilepsy (IGE) in humans are still not well understood, although the thalamus has frequently been invoked as the crucial structure in the generation of primary generalized seizures. The few in vivo magnetic resonance (MR)-based studies in IGE patients suggest an altered cortical/subcortical gray matter ratio, but with no evidence of structural alterations of the thalamus. In this study, we sought to determine the volumes of the other subcortical structures. METHODS: The volumes of the caudate nucleus, putamen, pallidum as well as the thalamus were each determined in both hemispheres in 11 patients with various IGE syndromes, normalized for whole-brain volumes and then compared with 15 age-matched controls. RESULTS: No differences were noted in thalamic volumes, confirming previous reports. However, smaller subcortical volumes were noted in the IGE patients (p < 0.009), mainly due to smaller putamen bilaterally (p < or = 0.015). CONCLUSIONS: It is speculated that the presence of discrete frontal dysfunction, as noted in neuropsychological studies in IGE patients, indirectly supports our results because the putamen projects predominantly to the frontal cortex. Larger studies with more homogeneous patient populations are needed to determine the robustness of these findings and whether they are specific for particular IGE syndromes.
