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1.
Contraception ; 103(6): 423-425, 2021 06.
Artigo em Inglês | MEDLINE | ID: mdl-33539801

RESUMO

INTRODUCTION: The Centers for Disease Control and Prevention recommend considering screening asymptomatic women for trichomonas in high-prevalence settings. Whether urban abortion clinics constitute such a setting is unknown. MATERIAL AND METHODS: We offered trichomonas screening to patients presenting for abortion from October 2018 to February 2019 as a practice improvement and conducted a chart review. RESULTS: Ninety-two percent (593/644) of patients underwent testing. Trichomonas prevalence was 10.0% (95% CI 7.7-12.6). Ninety five percent of patients diagnosed were treated. Testing only symptomatic patients would have missed 98% of infections. CONCLUSIONS: Trichomonas was highly prevalent, and universal testing and treatment was feasible in an urban abortion clinic.


Assuntos
Infecções Sexualmente Transmissíveis , Tricomoníase , Vaginite por Trichomonas , Trichomonas vaginalis , Instituições de Assistência Ambulatorial , Feminino , Hospitais Urbanos , Humanos , Gravidez , Prevalência , Tricomoníase/diagnóstico , Tricomoníase/epidemiologia , Vaginite por Trichomonas/diagnóstico , Vaginite por Trichomonas/epidemiologia
2.
Contraception ; 103(2): 116-120, 2021 02.
Artigo em Inglês | MEDLINE | ID: mdl-33075332

RESUMO

OBJECTIVE: To evaluate the efficacy of intramuscular methylergonovine maleate as prophylaxis against excessive bleeding when given after dilation and evacuation (D&E) at 20-24 weeks. STUDY DESIGN: We performed a randomized, double-blinded, placebo-controlled trial in patients without excessive bleeding requiring intervention after D&E completion. We administered study treatment within one minute of the end of the procedure. We primarily compared outcomes using a composite of indicators of excessive post-procedure blood loss (post-procedure measured blood loss exceeding 125 mL, uterine massage or compression for at least two minutes, administration of additional uterotonic medication, intrauterine balloon tamponade, uterine re-aspiration, blood transfusion, uterine artery embolization, hospital admission for bleeding, or major surgery). Secondary outcomes included individual indicator occurrences, satisfaction, and side effects. RESULTS: From March 3, 2015 to March 31, 2017, we randomized 284 participants (n = 140 methylergonovine, n = 144 placebo), five before we registered the trial with clinicaltrials.gov. Baseline characteristics were similar between groups. The composite outcome occurred in 78 (56%) methylergonovine and 75 (52%) placebo participants (p = 0.5). Methylergonovine recipients required more intrauterine balloon use (n = 20 [14%]) versus placebo (n = 10 [7%]), p = 0.04. We also observed a non-significant trend towards more uterotonic administration (n = 56 [40%] versus n = 43 [30%], p = 0.07) and hospital admissions for bleeding (n = 4 [3%] versus n = 0, p = 0.06) in the methylergonovine group compared to placebo. CONCLUSION: We observed no improvement in the composite outcome for excessive bleeding with prophylactic post-procedure methylergonovine. In addition, individual excessive bleeding outcomes occurred more frequently in the methylergonovine group, potentially indicating harm with its prophylactic use after D&E. IMPLICATIONS: When administered prophylactically immediately after dilation and evacuation abortion at 20-24 weeks, methylergonovine increases uterine bleeding. Given the lack of data for effectiveness as a prophylactic agent and our findings indicating harm, we do not recommend its use for post-operative prophylaxis.


Assuntos
Aborto Induzido , Aborto Espontâneo , Metilergonovina , Dilatação , Feminino , Humanos , Gravidez , Hemorragia Uterina/prevenção & controle
3.
Am J Obstet Gynecol ; 223(6): 892.e1-892.e12, 2020 12.
Artigo em Inglês | MEDLINE | ID: mdl-32640198

RESUMO

BACKGROUND: Adverse reproductive health outcomes are well documented among people experiencing homelessness or housing instability. Little is known about abortion outcomes among this population. OBJECTIVE: This study aimed to investigate the relationship between housing status and abortion outcomes and whether gestational age mediates this relationship. STUDY DESIGN: Our sample comprised 1903 individuals who had abortions at an urban clinic in San Francisco, CA, from 2015 to 2017. We defined homelessness or housing instability as a binary exposure, which included staying outside, with friends and/or family, or in a tent, vehicle, shelter, transitional program, or hotel. We evaluated gestational duration of ≥20 weeks as a mediator variable. Our primary outcome was any abortion complication. Logistic regression models were adjusted for age, race, substance use, mental health diagnoses, and previous vaginal and cesarean deliveries. RESULTS: Approximately 19% (n=356) of abortions were among people experiencing homelessness or housing instability. Compared with those with stable housing, people experiencing homelessness or housing instability presented later in pregnancy (mean gestational duration, 13.3 vs 9.5 weeks; P<.001) and had more frequent complications (6.5% vs 2.8%; P<.001; odds ratio, 2.2; 95% confidence interval, 1.2-3.9). Adjusting for race, substance use, mental health diagnoses, and previous cesarean deliveries, individuals experiencing homelessness or housing instability were more likely to have abortion complications (odds ratio, 2.3; 95% confidence interval, 1.3-4.0). However, the relationship was attenuated after adjusting for gestational duration (odds ratio, 1.4; 95% confidence interval, 0.7-2.6), suggesting that gestational duration mediates the relationship between housing status and abortion complications. CONCLUSION: Patients experiencing homelessness or housing instability presented later in gestation, which seems to contribute to the increased frequency of abortion complications.


Assuntos
Aborto Induzido , Dilatação e Curetagem , Idade Gestacional , Pessoas Mal Alojadas/estatística & dados numéricos , Complicações Pós-Operatórias/epidemiologia , Hemorragia Uterina/epidemiologia , Inércia Uterina/epidemiologia , Perfuração Uterina/epidemiologia , Abortivos/uso terapêutico , Adulto , Negro ou Afro-Americano , Asiático , Colo do Útero/lesões , Colo do Útero/cirurgia , Cesárea , Etnicidade/estatística & dados numéricos , Feminino , Hispânico ou Latino , Hospitalização , Humanos , Complicações Intraoperatórias/epidemiologia , Complicações Intraoperatórias/terapia , Lacerações , Modelos Logísticos , Transtornos Mentais/epidemiologia , Complicações Pós-Operatórias/terapia , Hemorragia Pós-Operatória/epidemiologia , Hemorragia Pós-Operatória/terapia , Gravidez , Estudos Retrospectivos , Fatores de Risco , São Francisco/epidemiologia , Transtornos Relacionados ao Uso de Substâncias/epidemiologia , Infecção da Ferida Cirúrgica/tratamento farmacológico , Infecção da Ferida Cirúrgica/epidemiologia , Serviços Urbanos de Saúde , Hemorragia Uterina/terapia , Inércia Uterina/terapia , Perfuração Uterina/terapia , População Branca , Adulto Jovem
4.
Contraception ; 101(5): 286-292, 2020 05.
Artigo em Inglês | MEDLINE | ID: mdl-32007418

RESUMO

Although only 1.3% of abortions in the United States are between 20 and 24 weeks' gestation, these procedures are associated with elevated risks of morbidity and mortality. Adequate cervical preparation before dilation and evacuation (D&E) at 20-24 weeks' gestation reduces procedural risk. For this gestational range, at least one day of cervical preparation with osmotic dilators is recommended before D&E. The use of overnight osmotic dilators alone is sufficient for most D&Es at 20-24 weeks' gestation. Dilapan-S® dilators require a shorter time to achieve maximum dilation, may be more effective than laminaria and may increase the likelihood of success on the first D&E attempt. The use of adjunctive mifepristone administered one-day pre-operatively at the time of osmotic dilator placement, should be considered because evidence demonstrates that it makes D&E subjectively easier at 20-24 weeks without increasing side effects. While older studies suggest that two-days of serial osmotic dilators provide greater dilation than one day of dilators, adjunctive mifepristone may be comparable to a second day of dilators. Adjunctive misoprostol administered on the day of D&E does not appear to affect initial cervical dilation and procedure time and compared with mifepristone is associated with more side effects, such as pain and nausea. Using overnight mifepristone and same-day misoprostol without osmotic dilators at 20-24 weeks' gestation lengthens D&E procedure time and appears to increase immediate complications, at least among less experienced providers. Some evidence shows the feasibility of same-day cervical preparation before D&E at 20-24 weeks using Dilapan-S® with adjunctive misoprostol or serial repeat dosing of misoprostol, but same-day preparation should be limited to providers with significant experience with these regimens. The Society of Family Planning recommends preoperative cervical preparation before D&E at 20-24 weeks' gestation. Further studies are needed to clarify the best means of preparing the cervix in order to minimize abortion complications and improve outcomes in this gestational range.


Assuntos
Abortivos , Aborto Induzido/métodos , Colo do Útero/efeitos dos fármacos , Cuidados Pré-Operatórios/métodos , Colo do Útero/fisiologia , Extração Obstétrica/métodos , Serviços de Planejamento Familiar/organização & administração , Feminino , Humanos , Primeira Fase do Trabalho de Parto/efeitos dos fármacos , Primeira Fase do Trabalho de Parto/fisiologia , Laminaria , Mifepristona , Misoprostol , Gravidez , Segundo Trimestre da Gravidez , Sociedades Médicas
6.
Obstet Gynecol ; 132(1): 171-178, 2018 07.
Artigo em Inglês | MEDLINE | ID: mdl-29889744

RESUMO

OBJECTIVE: To estimate the incidence of pulmonary aspiration and other anesthesia-related adverse events in women undergoing dilation and evacuation (D&E) under intravenous deep sedation without tracheal intubation in an outpatient setting. METHODS: We reviewed all D&Es done under anesthesiologist-administered intravenous deep sedation without tracheal intubation between February 2009 and April 2013. The study's primary outcome was pulmonary aspiration; secondary outcomes included other anesthesia-related complications. We calculated the incidence of anesthesia-related adverse events as well as a 95% CI around the point estimate. RESULTS: During the 51-month study period, 4,481 second-trimester abortions were completed. Of these, 2,523 (56%) were done under deep sedation without tracheal intubation, 652 (26%) between 14 and 19 6/7 weeks of gestation, and 1,871 (74%) between 20 and 24 weeks of gestation. Seven cases of anesthesia-related complications were identified: two cases of pulmonary aspiration (0.08%, 95% CI 0.01-0.29%), four cases of upper airway obstruction (0.016%, 95% CI 0.04-0.41%), and one case of lingual nerve injury (0.04%, 95% CI 0.001-0.22%). CONCLUSION: Deep sedation without tracheal intubation for women undergoing D&E has a low incidence of anesthesia-related complications.


Assuntos
Aborto Induzido/efeitos adversos , Sedação Profunda/efeitos adversos , Dilatação/efeitos adversos , Aspiração Respiratória/epidemiologia , Aborto Induzido/métodos , Adulto , Dilatação/métodos , Feminino , Idade Gestacional , Humanos , Incidência , Gravidez , Segundo Trimestre da Gravidez , Aspiração Respiratória/etiologia , Estudos Retrospectivos
7.
Contraception ; 97(5): 451-455, 2018 05.
Artigo em Inglês | MEDLINE | ID: mdl-29410259

RESUMO

OBJECTIVE: To compare estimated versus measured blood loss at the time of dilation and evacuation (D&E). STUDY DESIGN: We measured blood loss for all D&E procedures between 16 and 24 weeks at one abortion clinic over 9 months. We weighed all blood-containing items and measured blood captured in the D&E tray. Providers recorded estimated blood loss before weighing or measuring blood. We compared median measured blood loss (MBL) and estimated blood loss (EBL) for each gestational week. RESULTS: We measured blood loss in 371 of the 534 D&Es in the study period; we excluded 163 procedures because of failure to measure blood loss or contamination with amniotic fluid. Included and excluded procedures had similar median EBLs. Median EBL differed significantly from MBL for each week gestation from 16 to 24 weeks (p≤.001 for all comparisons); MBL was approximately twice as high as EBL for each gestational week. EBL and MBL increased with increasing gestation, as did the difference between EBL and MBL. CONCLUSION: Providers consistently and significantly underestimate blood loss at the time of D&E. D&E providers may want to consider using a new heuristic for estimating blood loss. IMPLICATIONS: Providers significantly underestimate blood loss at the time of D&E. Future research should confirm these findings (particularly at 22-24 weeks gestation), evaluate the efficacy of interventions to improve estimations of blood loss, and determine best practices for decreasing blood loss.


Assuntos
Perda Sanguínea Cirúrgica/estatística & dados numéricos , Dilatação e Curetagem/efeitos adversos , Aborto Induzido/métodos , Adolescente , Adulto , Criança , Feminino , Idade Gestacional , Humanos , Pessoa de Meia-Idade , Gravidez , Segundo Trimestre da Gravidez , Estudos Prospectivos , São Francisco , Adulto Jovem
8.
Arch Pathol Lab Med ; 141(2): 267-273, 2017 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-27763778

RESUMO

CONTEXT: -Despite increased use of dilation and evacuation in the setting of fetuses with developmental anomalies, the pathology examination of fragmented specimens obtained by this technique has been understudied. OBJECTIVES: -To correlate pathologic findings in second-trimester fetal dilation and evacuation specimens with prenatal diagnoses established through ultrasound and/or chromosome studies to determine the value of pathology examination for supplementing or correcting clinical diagnoses. DESIGN: -In this retrospective study, clinical and pathology findings were correlated in 448 dilation and evacuation specimens performed for second-trimester termination of pregnancy for fetal anomalies discovered on ultrasound examination (278 cases) or chromosome analysis (170 cases). RESULTS: -In 109 of the 170 cases with chromosomal abnormalities (64%), pathologists identified at least 1 congenital defect associated with the respective karyotype. In 278 cases with ultrasound-detected anomalies, pathologists confirmed the major congenital defect in 116 fetal specimens (42%). Evaluating for congenital central nervous system and body wall/diaphragm pathologic findings proved challenging owing to tissue disruption. However, taking all categories into account, pathology studies corrected ultrasound diagnoses in 152 of 413 cases (37%) and yielded additional diagnostic findings in 137 cases (33%). CONCLUSIONS: -In a substantial number of cases, examination of fragmented fetuses corrected or refined prenatal diagnoses, demonstrating a role for detailed pathology examination of dilation and evacuation specimens in quality control of prenatal imaging studies and for potentially aiding subsequent genetic counseling.


Assuntos
Anormalidades Congênitas/diagnóstico , Patologia Clínica , Diagnóstico Pré-Natal , Aborto Induzido , Estudos de Coortes , Feminino , Feto , Humanos , Gravidez , Estudos Retrospectivos
9.
Obstet Gynecol ; 126(3): 585-592, 2015 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-26244536

RESUMO

OBJECTIVE: To evaluate the association between obesity (body mass index [BMI] 30 or higher) and dilation and evacuation (D&E) complications. METHODS: We conducted a retrospective cohort study of women who underwent D&E abortion from February 2009 to April 2013 at a hospital-based abortion practice in California. We evaluated the association between obesity and risk of complication after D&E using logistic regression. We defined complications a priori as cervical laceration, hemorrhage, uterine atony, anesthesia complications, uterine perforation, disseminated intravascular coagulation, and retained products of conception. We defined major complications as those requiring hospitalization, transfusion, or further surgical intervention. RESULTS: Complications occurred in 442 of 4,520 D&Es (9.8%), with equal proportions in obese and nonobese women (9.8%). Major complications occurred in 78 (1.7%) patients. After adjustment for age, ethnicity, prior vaginal delivery, prior cesarean delivery, and gestational duration, there was no association between BMI and D&E complications. Any individual complication was associated with each additional week of gestation (odds ratio [OR] 1.3, 95% confidence interval [CI] 1.3-1.4), prior vaginal delivery (OR 1.5, 95% CI 1.2-1.9) and prior cesarean delivery (OR 1.8, 95% CI 1.4-2.3). Major complications were associated with each additional week of gestation (OR 1.3, 95% CI 1.1-1.4) and cesarean delivery (OR 1.8, 95% CI 1.1-3.1). CONCLUSION: We found no association between obesity and D&E complications. Our findings are consistent with previous studies demonstrating that later gestational duration is associated with an increased risk of complications. Obesity may not warrant referral to a high-risk abortion center, particularly because referral-associated delay might increase the risk of complications. LEVEL OF EVIDENCE: II.


Assuntos
Aborto Induzido/efeitos adversos , Dilatação e Curetagem/efeitos adversos , Obesidade/complicações , Complicações Pós-Operatórias/epidemiologia , Segundo Trimestre da Gravidez , Aborto Induzido/métodos , Adulto , Índice de Massa Corporal , California , Estudos de Coortes , Intervalos de Confiança , Bases de Dados Factuais , Dilatação e Curetagem/métodos , Feminino , Seguimentos , Humanos , Incidência , Obesidade/diagnóstico , Razão de Chances , Complicações Pós-Operatórias/fisiopatologia , Gravidez , Valores de Referência , Estudos Retrospectivos , Medição de Risco , Adulto Jovem
10.
Obstet Gynecol ; 126(3): 599-609, 2015 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-26196084

RESUMO

OBJECTIVE: To evaluate operative time after adjunctive misoprostol or mifepristone compared with overnight osmotic dilators alone for cervical preparation before dilation and evacuation at 16-23 6/7 weeks of gestation. METHODS: This double-blind, three-arm, multicenter, randomized trial compared overnight osmotic dilators alone, dilators plus 400 micrograms buccal misoprostol 3 hours preoperatively, and dilators plus 200 mg oral mifepristone during dilator placement for dilation and evacuation. Our primary outcome was dilation and evacuation operative time within two cohorts: 16-18 6/7 weeks of gestation (N=150) and 19-23 6/7 weeks of gestation (N=150). Three hundred women were required for 80% power to detect a 2-minute difference in operative time. Secondary outcomes included initial cervical dilation, side effects, physician satisfaction by Likert scale, and complications. RESULTS: Between February 2013 and February 2014 we randomized 300 women evenly across treatment arms. Group demographics were similar. We found no difference in operative time in either gestational cohort (early cohort [minutes]: 5.11±3.0 dilators alone, 4.99±3.3 misoprostol, 4.33±2.0 mifepristone, P=.34; late cohort [minutes]: 7.50±3.7 dilators alone, 7.62±5.4 misoprostol, 6.74±3.2 mifepristone, P=.53). In the early cohort, initial dilation was greater with misoprostol than dilators alone (2.4 compared with 2.0 cm, P=.007). Patients given misoprostol had significantly more pain, fever, and chills. In the late cohort, dilation and evacuation procedures were less difficult after mifepristone (4.1%, 95% confidence interval [CI] 0.0-9.6) than misoprostol (18.8%, 95% CI 7.7-29.8) or dilators alone (18.8%, 95% CI 7.7-29.8; P=.04). We had inadequate power to infer differences in complications: dilators alone (10%, 95% CI 4.2-16.0) compared with misoprostol (2%, 95% CI 0-4.7) compared with mifepristone (2%, 95% CI 0-4.8). CONCLUSION: Despite no difference in operative time, adjunctive mifepristone facilitates later dilation and evacuation compared with osmotic dilators alone and is better tolerated than misoprostol. CLINICAL TRIAL REGISTRATION: ClinicalTrials.gov, www.clinicaltrials.gov, NCT01751087. LEVEL OF EVIDENCE: I.


Assuntos
Aborto Induzido/métodos , Dilatação e Curetagem/instrumentação , Mifepristona/administração & dosagem , Misoprostol/administração & dosagem , Resultado da Gravidez , Abortivos não Esteroides/administração & dosagem , Adulto , Terapia Combinada , Dilatação e Curetagem/métodos , Método Duplo-Cego , Feminino , Seguimentos , Humanos , Gravidez , Segundo Trimestre da Gravidez , Cuidados Pré-Operatórios/métodos , Estudos Prospectivos , Medição de Risco , Instrumentos Cirúrgicos , Fatores de Tempo , Resultado do Tratamento , Adulto Jovem
11.
Contraception ; 92(6): 553-9, 2015 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-26093190

RESUMO

OBJECTIVE: Women who have abortions are at high risk of contraception discontinuation and subsequent unintended pregnancy. The objective of this analysis was to identify factors associated with choice of highly effective, long-acting, progestin-only contraceptive methods after abortion. STUDY DESIGN: Women presenting for surgical abortion who selected the levonorgestrel intrauterine device (IUD), the progestin implant or the progestin injection (depot medroxyprogesterone acetate or DMPA) as their postabortion contraceptives were recruited to participate in a 1-year prospective cohort study. We used multivariable multinomial logistic regression to identify factors associated with choosing long-acting reversible contraceptives (IUD or implant) compared to DMPA. RESULTS: A total of 260 women, aged 18-45 years, enrolled in the study, 100 of whom chose the IUD, 63 the implant and 97 the DMPA. The women were 24.9 years old on average; 36% were black, and 29% were Latina. Fifty-nine percent had had a previous abortion, 66% a prior birth, and 55% were undergoing a second-trimester abortion. In multivariable analyses, compared with DMPA users, women who chose the IUD or the implant were less likely to be currently experiencing intimate partner violence (IPV); reported higher stress levels; weighed more; and were more likely to have finished high school, to have used the pill before and to report that counselors or doctors were helpful in making the decision (all significant at p<.05, see text for relative risk ratios and confidence intervals.) In addition, women who chose the IUD were less likely to be black (p<.01), and women who chose the implant were more likely to report that they would be unhappy to become pregnant within 6 months (p<.05) than DMPA users. CONCLUSION: A variety of factors including race/ethnicity, past contraceptive use, feelings towards pregnancy, stress and weight were different between LARC and DMPA users. Notably, current IPV was associated with choice of DMPA over the IUD or implant, implying that a desire to choose a hidden method may be important to some women and should be included in counseling. IMPLICATIONS: In contraceptive counseling, after screening for IPV, assessing patient's stress and taking a history about past contraceptive use, clinicians should discuss whether these factors might affect a patient's choice of method.


Assuntos
Aborto Induzido/psicologia , Comportamento de Escolha , Anticoncepção/psicologia , Anticoncepcionais Femininos/administração & dosagem , Dispositivos Intrauterinos Medicados/estatística & dados numéricos , Adolescente , Adulto , Peso Corporal , Anticoncepção/métodos , Tomada de Decisões , Desogestrel/administração & dosagem , Implantes de Medicamento/uso terapêutico , Escolaridade , Feminino , Humanos , Violência por Parceiro Íntimo/psicologia , Violência por Parceiro Íntimo/estatística & dados numéricos , Levanogestrel/administração & dosagem , Modelos Logísticos , Acetato de Medroxiprogesterona/administração & dosagem , Pessoa de Meia-Idade , Análise Multivariada , Gravidez , Gravidez não Planejada/psicologia , Estudos Prospectivos , Grupos Raciais , Estresse Psicológico/psicologia , Adulto Jovem
12.
Contraception ; 92(3): 241-5, 2015 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-25998938

RESUMO

OBJECTIVES: Our survey aimed to characterize the practice of inducing fetal demise before pregnancy termination among abortion providers, including its technical aspects and why providers have chosen to adopt it. STUDY DESIGN: We conducted a survey of Family Planning Fellowship-trained or Fellowship-affiliated Family Planning (FP) subspecialists about their practice of inducing fetal demise, including questions regarding the circumstances in which they would induce demise, techniques used and rationales for choosing whether to adopt this practice. RESULTS: Of the 169 FP subspecialists we surveyed, 105 (62%) responded. About half (52%) of respondents indicated that they routinely induced fetal demise before terminations in the second trimester. Providers' practices varied in the gestations at which they started inducing demise as well as the techniques used. Respondents provided legal, technical and psychological reasons for their decisions to induce demise. CONCLUSION: Inducing fetal demise before second-trimester abortions is common among US FP specialists for multiple reasons. The absence of professional guidelines or robust data may contribute to the variance in the current practice patterns of inducing demise. IMPLICATIONS: Our study documents the widespread practice of inducing fetal demise before second-trimester abortion and further describes wide variation in providers' methods and rationales for inducing demise. It is important for abortion providers as a professional group to come to a formal consensus on the appropriate use of these techniques and to determine whether such practices should be encouraged, tolerated or even permitted.


Assuntos
Aborto Induzido/métodos , Serviços de Planejamento Familiar/métodos , Morte Fetal , Segundo Trimestre da Gravidez , Adulto , Idoso , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Gravidez , Especialização , Inquéritos e Questionários
13.
J Matern Fetal Neonatal Med ; 28(12): 1461-6, 2015 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-25164615

RESUMO

OBJECTIVE: Explore associations between neonatal providers' perspectives on survival, quality of life (QOL) and treatment recommendations. METHODS: Providers attending a workshop on neonatal viability were surveyed about survival, perceived QOL and treatment recommendations for marginally viable infants. We assessed associations between estimated survival and perceived QOL and treatment recommendations. RESULTS: In the 44 included surveys, estimates of survival and QOL varied widely. Maximum care was recommended 80% of the time when anticipated QOL was high, versus 20% when anticipated QOL was low (p < 0.001). Adjusted for confounders, odds of recommending maximum intervention were 4.4 times higher when anticipated QOL was high (95% CI 1.9 - 10.2, p = 0.001). CONCLUSIONS: The perspectives of practitioners who provide care to critically ill neonates regarding potential survival and QOL vary dramatically and are associated with the treatments those practitioners recommend. Practitioners should take care to avoid basing treatment recommendations on their own perspectives if they are not well aligned with those of the parents.


Assuntos
Estado Terminal/terapia , Pessoal de Saúde , Doenças do Recém-Nascido/terapia , Terapia Intensiva Neonatal , Qualidade de Vida , Adulto , Estado Terminal/mortalidade , Humanos , Recém-Nascido , Doenças do Recém-Nascido/mortalidade , Pessoa de Meia-Idade , Pais , Inquéritos e Questionários
15.
Am J Obstet Gynecol ; 211(2): 180.e1-3, 2014 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-24732003

RESUMO

The standard treatment for retained placenta is manual extraction, in which a hand is introduced inside the uterus to cleave a plane between the placenta and the uterine wall. For women without an epidural, the procedure is extremely uncomfortable and may require additional measures such as intravenous narcotics or regional anesthesia. Although ultrasound-guided instrumental removal of the placenta is standard practice as part of second-trimester abortion by dilation and evacuation and may be done at many institutions, especially after failed manual extraction, it has not yet been described in the literature as a technique following vaginal birth. Our experience with this technique is that it causes less discomfort to the patient than a traditional manual extraction, because the instrument entering the uterus is much narrower than a hand. With the patient in dorsal lithotomy, we locate the cervix and stabilize it either with fingers or a ring forceps on the anterior lip. We introduce Bierer ovum forceps into the uterus under direct ultrasound guidance. The Bierer forceps are preferred because of their long length, large head, and serrated teeth that allow for a firm, secure grip on the placenta. We grasp the placental tissue with the forceps and apply slow, gentle traction in short strokes, regrasping increasingly more distal areas of placenta as necessary to tease out the placenta. After 1-2 minutes, the placenta separates and can be pulled out of the uterus, usually intact. Our experience suggests that this technique is a well-tolerated option for women without an epidural who have a retained placenta. Further study is needed to quantify the amount of discomfort and anesthesia that can be avoided with this technique, as well as whether there is any change in the frequency of infectious complications or the necessity of postremoval curettage.


Assuntos
Forceps Obstétrico , Placenta Retida/diagnóstico por imagem , Placenta Retida/cirurgia , Tração , Ultrassonografia de Intervenção , Adulto , Parto Obstétrico , Feminino , Humanos , Gravidez
16.
Contraception ; 89(4): 307-13, 2014 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-24560477

RESUMO

OBJECTIVE: To describe the effectiveness of buccal misoprostol as an adjunct to laminaria for cervical ripening before later second-trimester abortion by dilation and evacuation (D&E). METHODS: A randomized, double-blinded, placebo-controlled trial of 196 women undergoing D&E between 21 and 23 weeks of gestation. Subjects had overnight laminaria and 400 mcg buccal misoprostol or placebo 3-4 h before the abortion. We used logarithmic transformation of the primary outcome--D&E procedure duration--to achieve a normal distribution. RESULTS: Mean D&E duration was 1.7 min shorter with misoprostol (p=.02). The median duration was 9.7 versus 10.4 min in the misoprostol and placebo groups, respectively (p=.09). Cervical dilation was slightly greater with misoprostol (median 75 mm vs. 73 mm, p=.04); however, physicians did not find the misoprostol D&Es easier to complete. Half of subjects reported severe pain after misoprostol vs. 11% with placebo (p<.001). CONCLUSION: Adjuvant buccal misoprostol results in slightly shorter D&Es at the cost of more side effects.


Assuntos
Abortivos não Esteroides/efeitos adversos , Aborto Induzido , Maturidade Cervical/efeitos dos fármacos , Misoprostol/efeitos adversos , Abortivos não Esteroides/administração & dosagem , Administração Oral , Adulto , Método Duplo-Cego , Feminino , Humanos , Laminaria , Misoprostol/administração & dosagem , Gravidez , Segundo Trimestre da Gravidez , Adulto Jovem
17.
Obstet Gynecol ; 123(2 Pt 1): 271-278, 2014 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-24402587

RESUMO

OBJECTIVE: To increase access to early second-trimester surgical abortion by determining noninferiority of same-day synthetic osmotic dilators compared with overnight Laminaria for cervical preparation before early second-trimester dilation and evacuation. METHODS: We enrolled women between 14 and 18 weeks of gestation and randomized them to same-day synthetic osmotic dilators or overnight Laminaria. Study participants and clinicians were blinded to group assignment. The primary outcome was procedure duration. The trial was powered to assess noninferiority of synthetic osmotic dilators to exclude a mean difference of 5 minutes or longer. RESULTS: We enrolled 72 patients: 36 were randomized to same-day synthetic osmotic dilators and 36 to overnight Laminaria. Mean procedure duration was 8.1 and 5.9 minutes, respectively, with a mean difference of 2.1 minutes (97.5% confidence interval -0.3 to 4.5). Same-day synthetic osmotic dilators resulted in less initial cervical dilation than overnight Laminaria (mean circumference 48 compared with 60 mm Pratt, P<.001) and required more mechanical dilation (69% compared with 27%, P=.001). There was no difference in complications, all of which were minor, or in the median procedural difficulty score rated by physicians. Most patients in both groups would choose a same-day procedure if necessary in the future. CONCLUSION: Despite less initial cervical dilation and a greater need for mechanical dilation, same-day synthetic osmotic dilators are not inferior to overnight Laminaria with respect to procedure duration. Same-day osmotic dilation is preferred by patients and may be a reasonable alternative to overnight Laminaria for cervical preparation before early second-trimester dilation and evacuation. CLINICAL TRIAL REGISTRATION: ClinicalTrials.gov, www.clinicaltrials.gov, NCT00775983. LEVEL OF EVIDENCE: I.


Assuntos
Aborto Induzido/métodos , Idade Gestacional , Primeira Fase do Trabalho de Parto , Laminaria , Adulto , Método Duplo-Cego , Feminino , Humanos , Satisfação do Paciente , Gravidez , Segundo Trimestre da Gravidez , Cuidados Pré-Operatórios , Curetagem a Vácuo , Adulto Jovem
18.
Contraception ; 89(1): 42-7, 2014 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-24176251

RESUMO

BACKGROUND: Immediate start of the contraceptive patch has not been studied in women after surgical abortion. STUDY DESIGN: Women presenting for surgical abortion who had chosen the transdermal patch for contraception were randomized to either delayed start of the patch (beginning the Sunday after their abortion) or immediate start (directly observed application of the patch in the clinic). Subjects were contacted at 2 and 6 months to assess contraceptive use. RESULTS: Two hundred ninety-eight women were randomized, and the follow-up rate was 71% at 2 months and 53% at 6 months. Method continuation did not differ by timing of initiation. At 2 months, 71% in the delayed-start group and 74% in the immediate-start group were using the patch [p=.6, with a difference of 3.1%, 95% confidence interval (CI)=-17.2% to +11.2%]. At 6 months, 55% in the delayed-start group and 43% in the immediate-start group were using the patch (p=.13, with a difference of 11.9%, 95% CI=-19.2% to +34%). CONCLUSION: Immediate initiation of the contraceptive patch after surgical abortion was not associated with increased use of patch at 2 or 6 months.


Assuntos
Anticoncepcionais Femininos/administração & dosagem , Acetato de Medroxiprogesterona/administração & dosagem , Aborto Induzido , Administração Cutânea , Adolescente , Adulto , Preparações de Ação Retardada , Feminino , Humanos , Cooperação do Paciente/estatística & dados numéricos , Fatores de Tempo , Adulto Jovem
19.
Contraception ; 88(6): 717-24, 2013 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-24094755

RESUMO

OBJECTIVE: We investigated whether more psychological distress before an abortion is associated with the effectiveness of contraception selected (low, moderate, or high effectiveness) at an abortion clinic visit. METHOD: Using data from 253 women attending an urban abortion clinic that primarily serves low-income women, we tested the association between pre-abortion psychological distress and the effectiveness level of post-abortion contraceptive choice. Based on typical use failure rates, we classified effectiveness of contraceptive choice into three levels-low, moderate, and high effectiveness. We measured psychological distress with four validated measures of depressive, anxious, and stress symptoms, and negative affect, as well as with a global measure comprising these four measures. We used multivariable ordinal logistic regression to measure the association of each psychological distress measure with post-abortion contraceptive method effectiveness level, adjusting for sociodemographic factors, pregnancy history, trimester of abortion, and importance of avoiding pregnancy in the next year. RESULTS: We found that compared to women experiencing less stress symptoms, negative affect and global psychological distress, women experiencing more stress symptoms [AOR=1.028, 95% CI: 1.001-1.050], negative affect [AOR=1.05, 95% CI: 1.01-1.09] and global psychological distress [AOR=1.46, 95% CI: 1.09-1.95] were more likely to choose more effective versus less effective methods, p<.05, in adjusted models. Using dichotomous psychological measures we found similar results. CONCLUSIONS: Women experiencing more psychological distress before an abortion selected more effective contraceptive methods after their abortion. Future research should examine whether this distress is associated with subsequent contraceptive use or continuation. IMPLICATIONS: The current study suggests that contraceptive providers should not assume that women experiencing more psychological distress prefer to use less effective contraceptive methods.


Assuntos
Aborto Induzido/psicologia , Comportamento Contraceptivo , Anticoncepção/métodos , Estresse Psicológico/psicologia , População Urbana , Adulto , Instituições de Assistência Ambulatorial , Comportamento de Escolha , Feminino , Humanos , Pobreza , Gravidez , Mulheres
20.
Am J Public Health ; 103(3): 454-61, 2013 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-23327244

RESUMO

OBJECTIVES: We examined the impact on patient safety if nurse practitioners (NPs), certified nurse midwives (CNMs), and physician assistants (PAs) were permitted to provide aspiration abortions in California. METHODS: In a prospective, observational study, we evaluated the outcomes of 11 487 early aspiration abortions completed by physicians (n = 5812) and newly trained NPs, CNMs, and PAs (n = 5675) from 4 Planned Parenthood affiliates and Kaiser Permanente of Northern California, by using a noninferiority design with a predetermined acceptable risk difference of 2%. All complications up to 4 weeks after the abortion were included. RESULTS: Of the 11 487 aspiration abortions analyzed, 1.3% (n = 152) resulted in a complication: 1.8% for NP-, CNM-, and PA-performed aspirations and 0.9% for physician-performed aspirations. The unadjusted risk difference for total complications between NP-CNM-PA and physician groups was 0.87 (95% confidence interval [CI] = 0.45, 1.29) and 0.83 (95% CI = 0.33, 1.33) in a propensity score-matched sample. CONCLUSIONS: Abortion complications were clinically equivalent between newly trained NPs, CNMs, and PAs and physicians, supporting the adoption of policies to allow these providers to perform early aspirations to expand access to abortion care.


Assuntos
Aborto Induzido/efeitos adversos , Enfermeiros Obstétricos , Profissionais de Enfermagem , Assistentes Médicos , Aborto Induzido/legislação & jurisprudência , Aborto Induzido/métodos , Adolescente , Adulto , California , Feminino , Humanos , Enfermeiros Obstétricos/legislação & jurisprudência , Profissionais de Enfermagem/legislação & jurisprudência , Segurança do Paciente , Assistentes Médicos/legislação & jurisprudência , Gravidez , Pontuação de Propensão , Estudos Prospectivos , Curetagem a Vácuo/efeitos adversos , Curetagem a Vácuo/legislação & jurisprudência , Curetagem a Vácuo/métodos , Adulto Jovem
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