RESUMO
A denitrifying bacteria, which we named Chelatococcus DNB-15, was screened and isolated from the Shengli Oilfield polymer-containing wastewater. The strain was characterized by 16S rDNA analysis and the effects of nutrient substrate type, pH, mineralization and temperature on the activity of the strain were also investigated. The strain was identified as Chelatococcus, of which the most efficient carbon source is sodium citrate, the most suitable nitrogen source is potassium nitrate, the suitable temperature for growth is 35ï½45 °C, the suitable pH range for growth is 7.0ï½9.0, and the maximal tolerable mineralization is 4 × 104 mg/L. The desulfurization experiment showed that Chelatococcus DNB-15 has desulfurization ability to some extent. When the initial sulfide concentration is lower than 50 mg/L, Chelatococcus DNB-15 grows rapidly, and the sulfides are removed quickly within 24 h, displaying a sulfur removal rate higher than 99 %; When the initial sulfide concentration is higher than 150 mg/L, the growth of Chelatococcus DNB-15 is severely restricted, the desulfurization effect is not obvious, and the desulfurization rate is almost stagnant.
RESUMO
As a potential therapeutic agent, the clinical application of S-nitrosoglutathione (GSNO) is limited because of its instability. Therefore, different formulations have been developed to protect GSNO from degradation, delivery and the release of GSNO at a physiological concentration in the active position. Due to the high water-solubility and small molecular-size of GSNO, the biggest challenges in the encapsulation step are low encapsulation efficiency and burst release. This review summarizes the different nano/micro-formulation strategies of a GSNO related delivery system to provide references for subsequent researchers interested in GSNO encapsulation.
