RESUMO
A novel alkaloid, hupcrispatine (1), has been isolated from the unique Chinese species Huperzia crispate Ching. The structure of hupcrispatine has been elucidated as 9-amino-6-methyl-3-quinolone on the basis of spectral evidence.
Assuntos
Alcaloides/química , Huperzia/química , Quinolinas/química , Estrutura MolecularRESUMO
To study the constituents of Rubus corchorifolius L. f, the constituents were separated by using various chromatographies and the structures were identified on the basis of chemical and spectral analysis. Two compounds were isolated from Rubus corchorifolius L. f. Their structures were identified as ent-kauran-3beta, 16beta, 17, 19-tetrol (1), ent-2-carbonyl-16beta-hydroxy-kauran-17-beta-D-glucoside (2). Compounds 1 and 2 are new compounds.
Assuntos
Diterpenos do Tipo Caurano/isolamento & purificação , Glucosídeos/isolamento & purificação , Rosaceae/química , Diterpenos do Tipo Caurano/química , Glucosídeos/química , Estrutura Molecular , Folhas de Planta/química , Plantas Medicinais/químicaRESUMO
OBJECTIVE: To study the effects of Dihydromyricetin (DMY) on antilipid-peroxidation. METHOD: The antilipid-peroxidation of DMY on heart, liver, brain tissue homogenate and mitochondria was measured by the determination of malondiadehyde (MDA) induced by Fe2+ -Vit C, Fe2+ -H2O2, Fe-Cys with TBA spectrometric method. RESULT: DMY could inhibit the lipid peroxidation of homogenate and mitochondria. The inhibition exhibited concentration-dependent manner. CONCLUSION: DMY has good antilipid-peroxidation effect, which is worth studing further.
Assuntos
Antioxidantes/farmacologia , Flavonóis/farmacologia , Peroxidação de Lipídeos/efeitos dos fármacos , Ampelopsis/química , Animais , Antioxidantes/isolamento & purificação , Encéfalo/metabolismo , Relação Dose-Resposta a Droga , Flavonóis/isolamento & purificação , Fígado/metabolismo , Masculino , Malondialdeído/metabolismo , Mitocôndrias/metabolismo , Dilatação Mitocondrial/efeitos dos fármacos , Miocárdio/metabolismo , Plantas Medicinais/química , RatosRESUMO
OBJECTIVE: To study chemical constituents of Ilex kudingcha. METHOD: The constituents were isolated by chromatographic method and the structures were identified on the basis of spectral analysis. RESULT: Seven compounds, lupeol(I); 3 beta-hydroxyl-lup-20(29)-ene-24-methyl ester(II); lup-20(29)-ene-3 beta-, 24-diol(III); beta-sitosterol(IV); ursolic acid(V); daucosterol (VI); mannitol were obtained(VII). CONCLUSION: I, III, VI and VII compounds were obtained from genus Ilex for the first time.
