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1.
Heliyon ; 10(10): e30974, 2024 May 30.
Artigo em Inglês | MEDLINE | ID: mdl-38784552

RESUMO

Although urban agriculture (UA) has been gaining greater attention as part of an effort toward sustainable urban development in China, empirical knowledge is limited. We conducted a discrete choice experiment with 756 residents of Shanghai. Overall, the results indicate that respondents supported UA as they tended to favor one of the UA scenarios presented. Residents prefer UA facilities that utilize environmentally friendly production, offer farming activities, and are equipped with dining facilities. Regularly scheduled educational activities hosted by UA facilities are preferred to those on an irregular basis. In terms of location, residents prefer UA facilities that are close by but do not necessarily want UA facilities to be right in front of them. There is a stronger preference for UA among highly educated populations, those with primary and secondary school students, and those with agricultural work experience. Additionally, various UA attributes affect residents' preferences; overall, there is a high degree of homogeneity in residents' preferences for various UA attributes. The marginal willingness to pay value is slightly higher than expected among the estimation results. There are three reasons for this outcome: the characteristics of UA as a recreational facility in China, the relatively high price level in Shanghai, and the impact of the COVID-19 pandemic.

2.
Int Arch Allergy Immunol ; 182(10): 917-931, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-33915552

RESUMO

Urticaria is a type of skin disease characterized by rapid onset of hives (superficial dermis edema, erythema, pruritus, or burning sensation). According to whether the natural course exceeds 6 weeks, urticaria can be divided into acute and chronic urticaria (CU). At present, the evaluation of CU activity mainly depends on the Urticaria Activity Score (UAS), but the evaluation indicators are relatively single, and we need more reliable experimental data for evaluation. We typically summarize advanced biomarkers and several related pathogenic pathways discovered in recent years on urticaria, including the cell adhesion/chemotaxis pathway, interleukin (IL)-6/Janus tyrosine kinase/STAT pathway, IL-17/IL-23 pathway, basophil- and mast cell-related pathway, coagulation/fibrinolysis-related pathways, single-nucleotide polymorphism, and some other pathways. This review aims to find appropriate biomarkers so that we can evaluate disease activity, discover novel therapeutic targets, and predict the patients' response more accurately to therapeutic agents.


Assuntos
Urticária/diagnóstico , Urticária/terapia , Animais , Basófilos/imunologia , Biomarcadores , Coagulação Sanguínea , Adesão Celular , Quimiotaxia , Citocinas/imunologia , Humanos , Mastócitos/imunologia , Polimorfismo de Nucleotídeo Único , Urticária/genética , Urticária/imunologia
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