[Newly developed atrial fibrillation among patients under active observation by an outpatient clinic].

We carried out prospective cohort study of incidence of new cases of atrial fibrillation (AF) in a sample of Moscow population (patients under observation in our policlinic). Total incidence of AF between 2003 and 2009 was 7.7 per 1000 patient/years, it was higher among men than among women. Incidence of AF progressively increased with age reaching maximum in age group more or equal 85 years. Most frequent baseline disease in patients with first appearance of AF was hypertensive disease (71%). Ischemic heart disease diagnosed according to strict criteria (postinfarction cardiosclerosis, revascularization procedures) was registered in 20.1%, diabetes - in 15.7%, chronic heart failure - in 13%, valvular heart disease - in 5.6%, and history of acute ischemic stroke - in 2.5% of patients.

[Detection of risk factors and early manifestations of cardiovascular diseases during ambulatory examination of working age persons].

We have studied prevalence of risk factors (RF) of cardiovascular diseases (CVD) recorded for statistical purposes in subjects of able bodied age during 10 year period of observation in a policlinic as well as prevalence of early and/or oligosymptomatic CVD manifestations in 11762 subjects of working age with RF of CVD development according to results of complex noninvasive examination of cardiovascular system in ambulatory conditions during the period from 2000 to 2009 year. Numbers of men and women were 45.3 and 54.7%, respectively. The program of examination included analysis of ECG, echocardiography (EchoCG), ultrasound examination of brachiocephalic vessels, 24-hour Holter ECG monitoring, exercise test on treadmill. In 2006 and 2007 complex examination was supplemented with 24-hour monitoring of arterial pressure, stress EchoCG, noninvasive arteriography. Complex ambulatory examination of subjects of working age with FR of CVD development with the use of noninvasive methods of functional diagnostics allowed to diagnose in 56% of studied persons various early and/or oligosymptomatic CVD manifestations which often appeared in combination, including ischemic heart disease (in 15%), hypertensive disease- (in 42%), cerebral atherosclerosis - (in 23.5%).

[Stratification of risk of cardiovascular complications in government employees and results of 10-year prospective observation].

We investigated prognostic value of the SCORE scale in working age government employees with 3 or more risk factors (RF) of cardiovascular diseases (CVD) and metabolic syndrome (MS, 2001 criteria) according to results of 10-year prospective observation in a policlinic. The study comprised 268 practically healthy men: 168 patients with 3 or more RF of CVD (mean age 47.76+/-6.9 years) (group 1) and 100 patients with MS (mean age 47.73+/-7.97 years) (group 2). Prospective follow up of group I patients with low or moderate CVD risk calculated with the SCORE scale demonstrated concordance of predicted and actual rates of lethal outcomes. In the group of patients with MS and high CVD risk lowering of number and level of RF took place due to in-depth examination and high compliance to therapy. This resulted in lowering of CVD and postponement rate their later development.

[Prevalence of atrial fibrillation among patients under observation by an outpatient clinic].

Prevalence of atrial fibrillation among patients attending our policlinic (2.44 and 3.78% in 2002 and 2009, respectively) was higher among men than among women and progressively increased with age achieving maximum in the group of patients aged more or equal 85 years. Paroxysmal and persistent forms were more frequent than permanent AF. Thromboembolic complications, heart failure and valvular heart disease were to a greater degree characteristic of permanent AF.