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1.
Bratisl Lek Listy ; 125(1): 12-16, 2024.
Artigo em Inglês | MEDLINE | ID: mdl-38041840

RESUMO

OBJECTIVE: The aim of this study was to determine the prevalence of Diastasis of the rectus abdominis muscles (DRAM) and pelvic floor muscle dysfunction (PFMD) in postpartum women. Design: The observational prospective study. MATERIAL: 150 of 180 women (83.3 %) from 6 weeks to 6 months postpartum, with a mean age of 33.1 years. METHODS: For diastasis examination, inter recti distance (IRD) was measured by a linear 2D ultrasound probe, 4.5 cm above the navel, in its area and 4.5 cm below the navel when lying on the back at rest and under a load test. The degree of DRAM was classified into four grades. Urinary leakage symptoms were assessed by the International Incontinence Consultation Questionnaire (ICIQ - UI SF). RESULTS: The first degree of diastasis during the load test was 38.1 % above the navel, 36.4 % in the navel area, and 23.7 % below the navel. The second degree of diastasis with load was 28.8 % above the navel, 21.2 % in the navel area, and 10.2 % below the navel. PFMD showed 31.3 % of women with mild symptoms of SUI, 32.2 % of women with grade 1 cystocele. CONCLUSION: The average IRD distance at rest and during the load test confirmed the first grade of DRAM out of four degrees of severity. Moderate and medium DRAM occurred according to location in an average of one-third of the cases. The highest percentage of DRAM was above the navel, and the lowest percentage below the navel. PFMD was detected in an average of one-third of cases. It is important to monitor these parameters with a view to improving the quality of life index in the future (Tab. 5, Ref. 22).


Assuntos
Diafragma da Pelve , Reto do Abdome , Adulto , Feminino , Humanos , Diafragma da Pelve/diagnóstico por imagem , Diafragma da Pelve/fisiologia , Período Pós-Parto , Prevalência , Estudos Prospectivos , Qualidade de Vida , Reto do Abdome/diagnóstico por imagem
2.
Ceska Gynekol ; 88(4): 273-278, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-37643908

RESUMO

BACKGROUND: Currently, there are not enough studies comparing the width of the linea alba in women with and without stress urinary incontinence in postpartum women. The primary aim of the study was to compare the width (IRD) in postpartum women with and without symptoms of stress urinary incontinence (SUI). The secondary aim of the study was to compare pelvic floor muscle morphometry in postpartum women with and without SUI symptoms. METHODS: IRD distance was measured with a linear probe via 2D US. Urinary leakage symptoms were assessed by the International Consultation on Incontinence Questionnaire (ICIQ - UI SF). Symptoms of overactive bladder were assessed by the Brief Urge Urinary Incontinence Symptoms Questionnaire (OAB-q). The functional status of the pelvic floor muscles was examined by manometry and pelvic floor muscle morphometry was examined by 3D/4D US. CONCLUSION: We compared IRD distance with and without SUI symptoms in postpartum women. The group of patients with stress urinary incontinence had a greater IRD distance at rest and during exercise compared to women without stress urinary incontinence. No worse pelvic floor muscle function and morphometry was found in women with SUI compared to women without SUI.


Assuntos
Incontinência Urinária por Estresse , Incontinência Urinária , Humanos , Feminino , Músculos Abdominais , Exercício Físico , Período Pós-Parto
3.
Ceska Gynekol ; 88(3): 180-185, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-37344183

RESUMO

BACKGROUND: Examination for the presence of diastasis of the rectus abdominis muscle and examination of the entire posture is very important in postpartum women. Currently, examination by 2D ultrasound, caliper and palpation is used. It is examined at rest and during stress tests. METHODS: Case study of a patient with diastasis of the direct abdominal muscle after a first spontaneous uncomplicated delivery at the age of 32 years. Examination to confirm diastasis of the rectus abdominis muscle - the width of linea alba was measured with a 2D linear probe by ultrasound 4.5 cm above the umbilicus, in the region of the umbilicus and 4.5 cm below the umbilicus. Lying on the back at rest, and with elevation of the lower limbs. The degree of severity was classified into four grades. A standard physiotherapy postural examination was performed. A part of the intervention was individual exercise with activation of the m. transversus abdominis to reduce diastasis of the direct abdominal muscles. The exercise program included postural adjustment, modification of breathing stereotype and quality, and activation of pelvic floor muscles. Exercises to reduce pain in the ligamentous apparatus and training in correct ergonomics were also performed. The dosage of exercise was 15 min per day in the 1st week of treatment, 2-4 week of treatment 20 min per day, 5-12 week of treatment 30 min per day, 5 days per week, for 12 weeks. CONCLUSION: The effect of exercise with activation of m. transversus abdominis on the reduction of diastasis of the direct abdominal muscle in the postpartum patient was objectively proven by the above mentioned objectification methods.


Assuntos
Diástase Muscular , Terapia por Exercício , Parto , Reto do Abdome , Adulto , Feminino , Humanos , Gravidez , Exercício Físico , Terapia por Exercício/métodos , Período Pós-Parto , Reto do Abdome/patologia
4.
BMC Womens Health ; 20(1): 241, 2020 10 27.
Artigo em Inglês | MEDLINE | ID: mdl-33109157

RESUMO

BACKGROUND: The aim of this study was to explore the personal views of female gynecologists regarding the management of POP with a particular focus on the issue of uterine sparing surgery. METHODS: A questionnaire based survey of practicing female gynecologists in the Czech Republic, Slovenia and Slovakia. RESULTS: A total of 140 female gynecologists from 81 units responded to our questionnaire. The majority of respondents stated they would rely on a urogynecologist to aid them with their choice of POP management options. The most preferred options for POP management were sacrocolpopexy and physiotherapy. Almost 2/3 of respondents opted for a hysterectomy together with POP surgery, if they were menopausal, even if the anatomical outcome was similar to uterine sparing POP surgery. Moreover, 81.4% of respondents, who initially opted for a uterine sparing procedure, changed their mind if the anatomical success of POP surgery with concomitant hysterectomy was superior. Discussing uterine cancer risk in relation to other organs had a less significant impact on their choices. CONCLUSIONS: The majority of female gynecologists in our study opted for hysterectomy if they were postmenopausal at the time of POP surgery. However, variation in information provision had an impact on their choice.


Assuntos
Histerectomia/estatística & dados numéricos , Procedimentos Cirúrgicos Obstétricos/métodos , Tratamentos com Preservação do Órgão/estatística & dados numéricos , Prolapso de Órgão Pélvico/cirurgia , Idoso , Feminino , Humanos , Histerectomia/métodos , Pessoa de Meia-Idade , Procedimentos Cirúrgicos Obstétricos/efeitos adversos , Tratamentos com Preservação do Órgão/métodos , Eslovênia , Telas Cirúrgicas , Inquéritos e Questionários , Resultado do Tratamento
6.
J Cancer Res Clin Oncol ; 142(11): 2397-402, 2016 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-27581738

RESUMO

BACKGROUND: This study describes the effect of rapid tumor growth of patients suffering from various grades of malignant ductal breast carcinoma associated with the gene expression of ECM protein emilin 1, in correlation with the number of gene copies of emilin 1 and degradation of tumor tissue proteins. METHODS: A total of 40 examined patients participated in the experiment (controls, n = 10, grades GI-GIII, each n = 10). After isolation of total mRNA, transcription of mRNA into the cDNA was performed. Quantification of gene expression changes was detected by the real-time PCR method. Analysis at the protein level was performed via Western blot method. RESULTS: During the detection of changes at the mRNA level, a significantly decreased level of emilin 1 in tumor tissues with grade II (about 54 ± 8 % lower than control) was identified. Protein-level analysis indicated an increased level of emilin 1 in tumors with grade I in comparison with control samples (about 10 ± 3 %). CONCLUSION: Obtained results demonstrated that the suppressive role of emilin 1 is related to the grade of growing breast tumors, and associated with increased hypoxia in the tumor microenvironment followed by elevated unfolding and degradation of tissue proteins.


Assuntos
Neoplasias da Mama/genética , Carcinoma Ductal de Mama/genética , Glicoproteínas de Membrana/genética , Western Blotting , Neoplasias da Mama/metabolismo , Carcinoma Ductal de Mama/metabolismo , Estudos de Casos e Controles , DNA Complementar/genética , DNA Complementar/metabolismo , Feminino , Dosagem de Genes , Expressão Gênica , Humanos , Glicoproteínas de Membrana/biossíntese , Gradação de Tumores , RNA Mensageiro/genética , RNA Mensageiro/metabolismo , Reação em Cadeia da Polimerase em Tempo Real
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