RESUMO
Highly accurate monthly runoff forecasts play a pivotal role in water resource management and utilization. This article proposes a coupling of variational modal decomposition (VMD) and the dung beetle optimization algorithm (DBO) with the gated recurrent unit (GRU) to establish a new monthly runoff forecasting model: the VMD-DBO-GRU. Initially, historical runoff data are decomposed via VMD. Subsequently, the parameters of the GRU are optimized using the DBO, and the decomposed monthly runoff components are inputted into the GRU neural network. Finally, the predictions for each component are consolidated to provide monthly runoff predictions. The model is then validated using monthly runoff data from the Ansha reservoir in Fujian, collected from 1980 to 2020. The results demonstrate a higher prediction accuracy of the VMD-DBO-GRU model compared to BP, SVM, GRU, VMD-GRU, DBO-GRU, and EMD-GRU models, providing a new alternative for conducting monthly runoff prediction.
Assuntos
Besouros , Monitoramento Ambiental , Animais , Algoritmos , Redes Neurais de Computação , FezesRESUMO
Purpose@#Circular RNAs (circRNAs) are a new class of RNA molecules whose function is largely unknown. There is a growing evidence that circRNAs play an important regulatory role in the progression of a variety of human cancers. However, the exact roles and the mechanisms of circRNAs in gastric cancer are not clear. In this study, we aimed to elucidate the mechanism of hsa_circ_0005556. @*Materials and Methods@#Real-time quantitative polymerase chain reaction was used to detect the expression of hsa_circ_0005556, miR-4270, and matrix metalloproteinase-19 (MMP19) in gastric cancer tissues and cell lines. The expression of hsa_circ_0005556 in gastric cancer cells was silenced by lentivirus, and cell proliferation, invasion, migration, and tumorigenesis in nude mice were assessed to evaluate the function of hsa_circ_0005556 in gastric cancer. @*Results@#The expression of hsa_circ_0005556 in gastric cancer tissues and gastric cancer cell lines was higher compared to normal controls. In vitro, the downregulation of hsa_ circ_0005556 significantly inhibited proliferation, migration, and invasion of gastric cancer cells. In vivo, the downregulation of hsa_circ_0005556 suppressed tumor growth in nude mice. @*Conclusions@#Our study shows that the hsa_circ_0005556/miR-4270/MMP19 axis is involved in proliferation, migration, and invasion of gastric cancer cells through the competing endogenous RNA (ceRNA) mechanism.
RESUMO
OBJECTIVE@#This study aimed to analyze the treatment for mandibular coracoid fractures retrospectively.@*METHODS@#A retrospective study on 37 patients with mandibular coracoid fractures treated at Department of Traumatic and Plastic Surgery, West China Hospital of Stomatology, Sichuan University from January 2010 to December 2015 was conducted. Eleven patients were treated conservatively, and 26 patients underwent surgical restoration and internal fixation. Mouth opening and pain degree were used as indicators to analyze treatment results.@*RESULTS@#The 37 cases of coracoid fractures accounted for 3.18% of the total mandibular fractures. The average age of patients was 38.05 years. Satisfactory results were obtained in both treatments. A considerable change in the degree of mouth opening before and after 6 months was found in the two groups. The pain degree before treatment and 1 day after operation, 1 day and 4 weeks after operation, and 4 weeks and 6 months after operation indicated that the two groups did not significantly differ. However, substantial changes between the two groups were found before treatment and 6 months after operation.@*CONCLUSIONS@#Conservative treatment is recommended for patients with linear, temporalis muscle-located, and non-displaced coracoid fractures. Surgical treatment is recommended for patients with large fractures and those with accompanying zygomatic arch and mandible fractures.
