[Optimization of the immunologic selection of donor-recipient pairs in transplantation of the kidney]. / Optimizatsiia immunologicheskogo podbora par donor-retsipient pri transplantatsii pochki.

Three functional models relating the integral index of transplantation outcome to a combination of immunogenetic status determinants in the members of the donor-recipient pair were constructed using statusometric techniques. These models for the first time make it possible to perform a quantitative assessment of the contribution of each of the 24 A and B locus HLA antigens and four blood groups of the recipient, of the role of coincidence and discrepancy among the determinants making up the combination, and to automate selection of the most suitable recipient for every donor kidney from waiting lists.

[Immunologic typing of splenic lymphocytes from human fetuses--donors of pancreatic islet cell cultures]. / Immunologicheskoe tipirovanie limfotsitov selezenki vnutriutrobnykh plodov cheloveka--donorov kul'tur ostrovkovykh kletok

To determine the HLA-phenotype of a potential donor of pancreatic islet cells, use was made of lymphocytes from 18-25-week-old human fetuses. The HLA-phenotype was clearly established in 39 out of 52 cases. In 13 cases, the authors failed to reveal histocompatibility antigens because of low viability of lymphocytes. The relationship was ascertained between the detectability of HLA-antigens in fetal donors and cytophysiological characteristics of islet cell cultures prepared from the pancreas.