Prevalence of metabolic syndrome among prediabetic Omani adults: a preliminary study.

BACKGROUND: Metabolic syndrome is a well-established risk factor for the development of coronary artery disease (CAD). A recent cross-sectional, community-based study revealed that 36.1% of Omani adults are prediabetic as per American Diabetes Association (ADA) criteria. The objectives of this study were to determine the prevalence of metabolic syndrome and its relationship to various risk factors in a prediabetic population. METHODS: Our study included 281 Omani prediabetic adults. The anthropometric, systolic, and diastolic blood pressure measurements together with lipid profile estimation were carried out. RESULTS: In this study, the prevalence of metabolic syndrome was found to be 45.9%, and the gender-based distribution was 30.8% for men and 58.9% for women. The stepwise multiple logistic regression model revealed that women are at higher risk of developing metabolic syndrome. Prediabetics with a body mass index (BMI) >or= 30.0 (kg/m(2)) and abnormal waist-to-hip ratio (WHR) have a higher risk of developing metabolic syndrome with odds ratios (OR) of 20.20 and 6.38, respectively. CONCLUSION: The prevalence of metabolic syndrome in this prediabetic study population was found to be higher than that of in the general population. Certain health promotion and disease prevention measures have been suggested. To the best of our knowledge, this is the first report on this subject.

Prevalence of prehypertension and associated cardiovascular risk profiles among prediabetic Omani adults.

BACKGROUND: The importance of prediabetes and prehypertension has been demonstrated in several studies especially for primary prevention of CVD. A recent community based cross-sectional study revealed that 40.9 percent Omani adults are prediabetics. This study was undertaken to estimate the prevalence of prehypertension and associated cardiovascular risk profiles in prediabetics. To best of our knowledge, this is the first report on this subject. METHODS: The study included 327 confirmed pre-diabetic Omani adults, who were analysed for their demographic, metabolic and behavioral characteristics. These characteristics were compared between the three different blood pressure groups to determine the CVD risk factors. Univariate and step-wise multiple logistic regression methods were used to carry out the analysis of the data. RESULTS: In this study, the prevalence of prehypertension was 54.1 percent. Males were at higher risk of developing prehypertension as compared to females (OR = 2.30, 95% CI: 1.21, 4.38; P < 0.01). The individuals with higher BMI have two fold more risk of developing prehypertension (OR = 2.25, 95% CI: 1.26, 4.02; P < 0.01). The increased level of OGT enhanced the risk of developing prehypertension (OR = 1.26, 95% CI: 1.06, 1.50; P < 0.01). CONCLUSION: A high prevalence of prehypertension (54.1%) exists in this study population. The major determinants of prehypertension in these prediabetic subjects were male gender, increasing dysglycemia and BMI. Appropriate intervention strategies have been suggested.