1.
J Virol
; 70(1): 663-6, 1996 Jan.
Artigo
em Inglês
| MEDLINE
| ID: mdl-8523590
RESUMO
We previously demonstrated that expression of bcl-2 in Madin-Darby canine kidney (MDCK) cells blocks influenza virus-induced apoptosis and DNA fragmentation. We show here that expression of bcl-2 also reduces the level of infectious virus production and the spread of virus in MDCK cell cultures infected at a low multiplicity of infection. This effect is associated with modified glycosylation of the hemagglutinin protein.