RESUMO
We report two patients admitted to our hospital suspected to suffer from cancer in the lung or mediastinum, respectively. Both patients had a diagnosis of thoracic actinomycosis. A 76 year old man revealed pulmonary and endobronchial actinomycosis associated with broncholithiasis. Diagnosis was achieved by bronchoscopy. Therapy with ampicillin/sulbactam was successful. A 36 year old patient presented with bilateral pleural effusions, extended pericardial, mediastinal and pulmonary actinomycosis with pericarditis constrictiva and superior vena cava syndrome. Diagnosis was finally made by cardiac surgery with therapeutic pericardectomy. Prolonged therapy with ampicillin/sulbactam was administered with satisfactory result. Here we discuss the importance to include actinomycosis in the differential diagnosis of pulmonary affections and mediastinal masses in order to avoid diagnostic errors and to limit invasive procedures to the necessary amount. We illustrate the need of an individualized treatment approach.
Assuntos
Actinomicose/diagnóstico , Actinomicose/terapia , Doenças Torácicas/diagnóstico , Doenças Torácicas/terapia , Adulto , Idoso , Diagnóstico Diferencial , Humanos , Neoplasias Pulmonares/diagnóstico , Neoplasias Pulmonares/terapia , Masculino , Neoplasias do Mediastino/diagnóstico , Neoplasias do Mediastino/terapiaAssuntos
Doenças da Aorta/patologia , Febre Reumática/patologia , Aorta/patologia , Valva Aórtica/patologia , Calcinose/patologia , Cartilagem/patologia , Endotélio Vascular/patologia , Doenças das Valvas Cardíacas/patologia , Próteses Valvulares Cardíacas , Humanos , Masculino , Pessoa de Meia-Idade , Valva Mitral/patologiaRESUMO
Seminal plasma was tested against purified C1q by double diffusion. Precipitation reactions were frequently observed in the seminal plasma of patients with normozoospermia and patients with azoospermia; most of these reactions were not due to soluble immune complexes binding to C1q. A factor resistant to DNAse and RNAse (mol wt: 25,000--150,000 daltons) was found to precipitate C1q. Its discovery adds to the list of substances which may interfere in C1q precipitation tests.
Assuntos
Complemento C1/análise , Precipitinas/análise , Sêmen/imunologia , Cromatografia em Gel , Desoxirribonucleases/farmacologia , Humanos , Síndrome de Klinefelter/imunologia , Masculino , Oligospermia/imunologia , Ribonucleases/farmacologiaRESUMO
Seminal proteins (IgA, IgG, albumin) were measured in normozoospermic patients and in patients with normozoospermia associated with agglomerations of spermatozoa. The type of agglomeration was not taken into account. A slight yet significant increase in seminal IgA was detected in patients with agglomerations whereas the other proteins remained unchanged. By testing seminal plasma against C1q by double diffusion it was shown that many patients of both groups had nonimmune C1q precipitins. The significance of such precipitins in semen is not known.
