RESUMO
The results of the ultrastructural study of the epithelium of the patient cervix infected by the human papillomavirus (HPV) types 16 and 18 before and after treatment by contrasting thermo-laser therapy (CTLT) are presented. It was shown in this work that 1.5 and 6 months after treatment HPV DNA was not detected in the biopsy and the smear of the cervix using the polymerase chain reaction (PCR). In the ultrathin sections, the structure of the epithelial cells from the biopsy after treatment corresponded to norm. There was effective elimination of HPV types 16 and 18 as Induces by CTLT method.
Assuntos
Colo do Útero , Papillomavirus Humano 16/ultraestrutura , Papillomavirus Humano 18/ultraestrutura , Terapia a Laser , Infecções por Papillomavirus , Adulto , Colo do Útero/cirurgia , Colo do Útero/ultraestrutura , Colo do Útero/virologia , Epitélio/ultraestrutura , Epitélio/virologia , Feminino , Humanos , Infecções por Papillomavirus/patologia , Infecções por Papillomavirus/cirurgiaRESUMO
Elimination of types 16 and 18 human papilloma virus from the surface of cervix uteri for secondary prevention of cervical cancer was evaluated. The method is protected by patent of invention of the Russian Federation. Infrared laser therapy of cervix uteri was carried out in patients with precancer diseases of cervix uteri at Department of Gynecology of Municipal Clinical Hospital No. 52 (Moscow). Papillomavirus infection was eliminated using a Russian diode laser (lambda=1.06 µ, radiation power 10 W) with a collimating headpiece using carbon die at a distance of 10-12 cm from the exposed surface. The treatment resulted in a high percentage of elimination of types 16 and 18 oncogenic virus 4-6 weeks and during delayed periods after exposure.