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Zh Mikrobiol Epidemiol Immunobiol ; (2): 67-71, 1988 Feb.
Artigo em Russo | MEDLINE | ID: mdl-2452539

RESUMO

Tomicide, a preparation with antibacterial properties, accumulates in the culture medium during the growth of one of streptococcal strains. The injection of the preparation into mice simultaneously with the antigen (sheep red blood cells) produces an adjuvant effect. Tomicide has been found capable of inducing the production of interferon detected in the serum of the animals. During experimental stress created by intensive exercise tomicide prevented a decrease in the normal (anamnestic) level of antibodies, produced an immunostimulating effect and, at the same time, enhanced the total physical endurance of the animals, manifested by an increased duration of swimming.


Assuntos
Adjuvantes Imunológicos/farmacologia , Antibacterianos/farmacologia , Animais , Anticorpos/análise , Anticorpos Antibacterianos/análise , Especificidade de Anticorpos/efeitos dos fármacos , Bacteriocinas , Clostridium tetani/imunologia , Eritrócitos/imunologia , Imunização , Indutores de Interferon/farmacologia , Interferons/sangue , Camundongos , Resistência Física/efeitos dos fármacos , Staphylococcus/imunologia , Estresse Fisiológico/imunologia
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