[Current status and perspectives in hospital treatment of patients with tuberculosis complicated with alcohol abuse]. / Sostoianie i perspektivy statsionarnogo lecheniia bolnykh tuberkulëzom, zloupotrebliaiushchikh alkogolem.

The authors show a rise in the prevalence of tuberculosis among alcoholics. In the past decade, the specific proportion of these two concurrent diseases has reached 30% among the groups registered in the tuberculosis dispensaries. In a great number of patients, the disease was accompanied by bacterial secretion and decay. The therapeutical efficacy of compulsory treatment inpatients who refuse to take drugs has proved to be low. A daytime hospital can be one of treatments of such patients as the second stage of therapy after tuberculosis patients suffering from alcoholism have stayed in a twenty-four-hour hospital.

[Pulmonary tuberculosis in patients with mental disorders, drug addiction and substance abuse]. / Tuberkulez legkikh u bol'nykh s psikhicheskimi zabolevaniiami, narkomaniei i toksikomaniei.

The clinical manifestations, course and outcomes of pulmonary tuberculosis were studied in 215 patients with concurrent severe mental diseases (112 had schizophrenia and 103 other organic diseases of the central nervous system). The patients had mainly disseminated pulmonary tuberculosis with copious bacilli excretion and destruction. Their clinical manifestations and the course of a specific process were mainly progressive. Fatal outcomes were most common in tuberculosis patients with concurrent drug addiction and toxicomania. It is recommended that patients with mental diseases, narcomania and toxicomania should undergo a prophylactic fluorographic screening twice a year. Treatment of patients with tuberculosis and concurrent mental diseases should be combined and carried out by a psychiatrist (narcologist) jointly with a phthisiatrist.

[Incidence of pulmonary tuberculosis associated with chronic alcoholism and a complex treatment of those diseases]. / Rasprostranennost' tuberkuleza legkikh v sochetanii s khronicheskim alkogolizmom i kompleksnoe lechenie étikh zabolevanii.

It was shown that the prevalence of alcoholism among pulmonary tuberculosis patients was high and the outcomes of both the diseases proceeding in the presence of lowered immunity were often unfavourable, including the results of long-term follow-ups. The use of a specially constructed instrument for investigating the neurodynamic characteristics of the cerebral cortex and determination of gamma-glutamyl transpeptidase in the serum promoted diagnosis of prenosological entities of alcoholism. Higher efficacy of alcoholism treatment in the patients with tuberculosis was achieved with narcotic psychotherapy using the mixture of nitrous oxide and oxygen, esperal implantation and application of rifusal, a new preparation, as well as application of extracorporeal hemosorption and enterosorption for eliminating the intoxication. Higher efficacy of tuberculosis treatment in the alcoholic patients was achieved with intravenous drop-wise infusion of antituberculous drugs along with other routes of administration. For increasing the cellular immunity, the patients were treated with chlorophylliptum or T-activin. Continuation of the complex antialcoholic and antituberculous treatment of outpatients along with simultaneous observation by phthisiologists and narcologists provided higher results.