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1.
Sci Rep ; 14(1): 7124, 2024 03 26.
Artigo em Inglês | MEDLINE | ID: mdl-38531928

RESUMO

This study evaluates the effects of a green tea (Camellia sinensis) and hyaluronic acid gel on fibroblast activity and alveolar bone repair following third molar extractions. By examining the gene expression related to cell survival, proliferation, and angiogenesis, the study bridges in vitro findings with clinical outcomes in a split-mouth randomized trial. Human fibroblasts were exposed to the treatment gel, analysing gene expression through RT-qPCR. Twenty participants undergoing bilateral third molar extractions received the test gel on one side and a placebo on the other. Assessments included patient-reported outcomes, professional evaluations, and radiographic analyses at multiple postoperative intervals. The test gel significantly enhanced AKT, CDKs, and VEGF gene expressions, indicating a positive effect on angiogenesis and cell proliferation. Clinically, it resulted in reduced exudate, swelling, and secondary interventions, with radiographs showing improved alveolar bone density after 90 days. The green tea and hyaluronic acid gel significantly improves soft tissue and bone healing post-extraction, offering a promising adjunctive therapy for enhancing postoperative recovery. This gel represents a novel adjuvant treatment option for facilitating improved healing outcomes after third molar extractions, highlighting its potential utility in clinical dental practice.


Assuntos
Camellia sinensis , Ácido Hialurônico , Humanos , Chá , Dente Serotino/cirurgia , Extração Dentária/métodos
2.
J Prosthodont Res ; 60(2): 138-42, 2016 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-26481059

RESUMO

INTRODUCTION: Regarding implant-supported prostheses, the most reported types of complications are related to loosening or fracturing of abutment or prosthesis screws. This case report shows a series of procedures that allowed a conservative solution for a fractured screw. It avoided removing the implant and also allowed the same prosthesis to be used after guided-drilling the fractured screw and re-tapping the implant internal threads. The same prosthesis was replaced immediately after the procedure. PATIENT: A 67-year-old male patient, who had a fractured abutment screw of the lower left first molar implant. The patient decided for the conservative treatment option and an attempt was made to remove the fractured screw. DISCUSSION: Parafunctional habits can generate excessive occlusal forces, which are risk factors associated with loosening and fracturing implant screws and even the fixtures themselves. This case report focus on the probable causes, difficulties and risks associated with this procedure and it also discusses the alternative approaches. CONCLUSION: The purposed treatment allowed a time and money saving resolution for fractured abutment screws.


Assuntos
Parafusos Ósseos , Dente Suporte , Implantação Dentária Endóssea , Remoção de Dispositivo/métodos , Falha de Equipamento , Falha de Prótese , Idoso , Humanos , Masculino
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