Does Target Object Processing Affect Reaction Times in Simple Detection Spatial Cueing Tasks?

The current study tested the effect of varying target type and target set size during simple detection versions of Posner's exogenous spatial cueing task. The four target conditions consisted of a single letter, a single number, one of four possible letters, or one of four possible numbers. Responses were faster for numbers than for letters, but only when the cue-target lag was short, the target set included more than one potential number, and the cue and target appeared in different locations. These findings suggest that even during detection tasks, responses are influenced by the object features of the target. Methodological implications for spatial cueing studies and other types of visual perception research were discussed.

The effect of skin thickness and time in the absorption of dexamethasone in human tendons using iontophoresis.

STUDY DESIGN: Experimental laboratory study. OBJECTIVES: To measure the transmission of dexamethasone sodium phosphate (DEX-P) using iontophoresis as a function of skinfold tissue thickness and time elapsed between treatment and tissue extraction. BACKGROUND: Iontophoresis is a modality used in physical therapy with the intent to drive medications through the skin to underlying tissues using a direct electrical current. DEX-P is the most commonly used medication with iontophoresis and is used to treat a variety of connective tissue conditions. METHODS AND MEASURES: Sixteen adults undergoing anterior cruciate ligament reconstructive surgery using the semitendinosis/gracilis autograft received a 40-mA-min dose of iontophoresis with 0.4% DEX-P superficial to a slip of the distal semitendinosis tendon prior to surgery. The tendon slip was extracted within 4 hours. Time between treatment and tissue extraction and skinfold thickness were measured. Analysis was performed on the slip of the semitendinosis using high-performance liquid chromatography mass spectrum. RESULTS: Of the 16 subjects (10 female, 6 male; mean age, 33 years), 7 had measurable amounts of DEX-P in the tendon slip (4 female, 3 male; mean age, 34 years). The average concentration in the 16 subjects was 2.9 ng/g of tendon tissue. There was no correlation between DEX-P absorbed and skinfold thickness (r = -0.08, P = .79) or time elapsed (r = 0.25, P = .38). In a subset of the 7 individuals that showed measurable levels of DEX-P absorbed, the average concentration of DEX-P was 6.6 ng/g of tendon tissue, and there was a relationship between DEX-P concentrations and time elapsed that did not reach statistical significance (r = 0.71, P = .11). CONCLUSIONS: Iontophoresis appears to facilitate the transmission of dexamethasone to connective tissues in humans with skinfold thickness up to at least 30 mm. The absorption of the dexamethasone seemed to continue to occur for up to 4 hours after delivery. It is not clear why DEX-P was measured in only 7 of the 16 subjects. LEVEL OF EVIDENCE: Therapy, level 5.

A meta-analysis of the 2004 campaign polls: an analogy to practice and publication in psychology.

The current practice of relying on single sample null hypothesis tests is being re-evaluated in the behavioral sciences. To highlight the issues raised by both sides of this discussion, a meta-analysis of The Gallup Organization's most recent U.S. Presidential election polling data was conducted. During the 2004 Presidential campaign, most pre-election polling percentages reported Bush ahead of Kerry, although the differences between the voters' preferences were typically within the margin of error. The meta-analyses used in this study showed significant differences between the two candidates' polling percentages, thus yielding a more accurate prediction than the conventional analysis which was based on single samples. These improved predictions provide support for a continued discussion about potential changes in statistical approaches to psychology.