Neurorretinitis por Bartonella henselae en Gipuzkoa, 2014-2019 / Neuroretinitis caused by Bartonella henselae in Gipuzkoa, 2014-2019

Introducción: Bartonella henselae causa la enfermedad por arañazo de gato (EAG), transmitida por arañazo o mordedura de gato, su principal reservorio. En ocasiones produce neuritis óptica o neurorretinitis.Objetivo: Revisar estas dolencias en Gipuzkoa (España), 2014-2019. Métodos: Revisión retrospectiva de registros serológicos y clínicos, seleccionando aquellos con manifestaciones clínicas compatibles, contacto con gatos y serología positiva para B. henselae (IFI-IgG≥1/256). Resultados: Sesenta y cuatro pacientes presentaron EAG; entre estos, uno tenía neuritis óptica y 3, neurorretinitis (4/64, 6,3%). En 3 casos un cuadro pseudogripal precedió a los síntomas oculares; 2 presentaron pérdida de agudeza visual al alta, a pesar del tratamiento prolongado con antibióticos y corticoides. Conclusión: La neuritis óptica y la neurorretinitis por B. henselae son complicaciones graves que presentan una incidencia no despreciable entre los pacientes con EAG de Gipuzkoa. Recomendamos descartar la EAG en pacientes con síntomas de neuritis óptica o neurorretinitis (pérdida brusca de visión, etc.) y contacto con gatos.(AU)

Introduction: Bartonella henselae causes cat scratch disease (CSD), spread by a cat scratch or bite. Cats are its main reservoir. This sometimes results in optic neuritis or neuroretinitis. Objective: To review these conditions in Gipuzkoa (Spain), 2014-2019. Methods: A retrospective review of serology and clinical records, selecting those with consistent clinical signs, contact with cats and positive serology for B. henselae (IgG-IFA≥1/256). Results: Sixty-four patients had CSD. Of these, one had optic neuritis and 3 had neuroretinitis (4/64; 6.3%). In 3 patients, flu-like symptoms preceded eye symptoms. Two suffered from loss of visual acuity at discharge, despite prolonged treatment with antibiotics and corticosteroids. Conclusion: Optic neuritis and neuroretinitis caused by B. henselae are severe complications with a non-negligible incidence among patients with CSD in Gipuzkoa. We recommend ruling out CSD in patients with symptoms of optic neuritis or neuroretinitis (sudden vision loss, etc.) and contact with cats.(AU)

Neuroretinitis caused by Bartonella henselae in Gipuzkoa, 2014-2019.

INTRODUCTION: Bartonella henselae causes cat scratch disease (CSD), spread by a cat scratch or bite. Cats are its main reservoir. This sometimes results in optic neuritis or neuroretinitis. OBJECTIVE: To review these conditions in Gipuzkoa (Spain), 2014-2019. METHODS: A retrospective review of serology registries and clinical registries, selecting those with consistent clinical signs, contact with cats and positive serology for B. henselae (IgG-IFA ≥1/256). RESULTS: Sixty-four patients had CSD. Of these, one had optic neuritis and 3 had neuroretinitis (4/64; 6.3%). In 3 patients, flu-like symptoms preceded eye symptoms. Two suffered from loss of visual acuity at discharge, despite prolonged treatment with antibiotics and corticosteroids. CONCLUSION: Optic neuritis and neuroretinitis caused by B. henselae are severe complications with a non-negligible incidence among patients with CSD in Gipuzkoa. We recommend ruling out CSD in patients with symptoms of optic neuritis or neuroretinitis (sudden vision loss, etc.) and contact with cats.

Neuroretinitis caused by Bartonella henselae in Gipuzkoa, 2014-2019. / Neurorretinitis por Bartonella henselae en Gipuzkoa, 2014-2019.

INTRODUCTION: Bartonella henselae causes cat scratch disease (CSD), spread by a cat scratch or bite. Cats are its main reservoir. This sometimes results in optic neuritis or neuroretinitis. OBJECTIVE: To review these conditions in Gipuzkoa (Spain), 2014-2019. METHODS: A retrospective review of serology and clinical records, selecting those with consistent clinical signs, contact with cats and positive serology for B. henselae (IgG-IFA≥1/256). RESULTS: Sixty-four patients had CSD. Of these, one had optic neuritis and 3 had neuroretinitis (4/64; 6.3%). In 3 patients, flu-like symptoms preceded eye symptoms. Two suffered from loss of visual acuity at discharge, despite prolonged treatment with antibiotics and corticosteroids. CONCLUSION: Optic neuritis and neuroretinitis caused by B. henselae are severe complications with a non-negligible incidence among patients with CSD in Gipuzkoa. We recommend ruling out CSD in patients with symptoms of optic neuritis or neuroretinitis (sudden vision loss, etc.) and contact with cats.

Saccharomyces cerevisiae vaginitis: microbiology and in vitro antifungal susceptibility.

Genitourinary infections by Saccharomyces cerevisiae are rare. Here, we describe eight S. cerevisiae vulvovaginitis episodes where molecular (Affirm VPIII) and conventional microbiological methods (culture and carbohydrate assimilation) have proven to be inadequate for diagnostic purposes. DNA sequencing allowed the correct identification of the pathogen. All isolates were susceptible to most antifungal agents, with two of them also found to be susceptible-dose-dependent to itraconazole.