Assessment of autonomic function in the late term fetus: The effects of sex and state.

Researchers have reported associations between fetal sex and heart rate (FHR) and heart rate variability (FHRV) but rarely in the context of fetal behavioral sleep state. We examined differences in measures of fetal autonomic function by sex and sleep state. Fetal abdominal ECG monitoring technology was used to measure FHR and two measures of FHRV-standard deviation of FHR (SD) and beat-to-beat variability (RMSSD). FHR and movement patterns were also recorded with standard Doppler ultrasound monitor technology employed to code sleep states. Data were collected from 82 healthy fetuses ranging from 36 to 39 weeks gestation. A one-way MANOVA showed that FHR was significantly lower and SD was significantly higher for males than females. Independent samples t tests found that these sex differences were only in the active sleep state. There were no significant differences in RMSSD by sex. Repeated measures MANOVA for a subset that exhibited more than one state (N = 22) showed that SD was significantly different by state. RMSSD showed a marginally significant sleep state difference. In conclusion, fetal sex differences in HR and HRV may indicate more mature autonomic functioning in near-term males than females and fetal sleep state can influence abdominal fECG derived measures of FHR and FHRV.

Maternal depression during pregnancy is associated with increased birth weight in term infants.

Previous research of maternal depression during pregnancy suggests an association with low birth weight in newborns. Review of these studies reveals predominant comorbidity with premature birth. This current study examines antenatal depression and birth weight in term, medically low-risk pregnancies. Maternal physiological and demographic measures were collected as well. In total, 227 pregnant women were recruited to participate in four experimental protocols at Columbia University Medical Center. Results indicate that depressed pregnant women who carry to term had significantly higher heart rates, lower heart rate variability, and gave birth to heavier babies than those of pregnant women who were not depressed. Low income participants had significantly higher levels of depression, as well as significantly higher heart rates and lower heart rate variability, than those in higher income groups. In full-term infants, maternal prenatal depression appears to promote higher birth weight, with elevated maternal heart rate as a likely mediating mechanism.

A Comparison of Mental Health and Alcohol Use Between Traditional and Nontraditional Students.

OBJECTIVE: To describe differences in life stress, anxiety, depression, and alcohol use between traditional and nontraditional college students. PARTICIPANTS: A targeted, stratified sample of college students (N = 1,187; Mage = 23.96, SD = 7.30; female, 67.2%) completed study surveys in Spring 2011. METHODS: Participants completed demographic information, life stress (Crisis in Family Systems), anxiety (Beck Anxiety Inventory), depression (Center for Epidemiologic Studies Depression Scale), and alcohol use (Alcohol Use Disorders Identification Test-Consumption) surveys during regularly scheduled class times. RESULTS: Fifty-three percent (n = 630) of study participants were nontraditional students. Nontraditional students scored significantly higher than traditional students on life stress (t[1182] = -3.05, p < .01), anxiety (t[1175] = -2.20, p < .05), and depression (t[1174] = -2.22, p < .05). Nontraditional and traditional students did not differ on alcohol use. CONCLUSIONS: Interventions for nontraditional college students should address the mental health issues specific to this growing college subpopulation.