RESUMO
Pneumonia is a rare but serious complication of varicella during pregnancy. Maternal mortality has been reported to be 41% with fetal and neonatal mortality at 65%. Treatment has included respiratory support and prophylactic antibiotics. Acyclovir has been prescribed with the intent to decrease the impact of the infection. It was added to the treatment protocol of two cases of varicella pneumonia in pregnancy. Despite the high maternal and perinatal mortality both pairs of patients and infants survived. Acyclovir did not appear to adversely influence the fetus, and may have contributed to the survival of mother and child.
Assuntos
Aciclovir/uso terapêutico , Varicela/tratamento farmacológico , Pneumonia Viral/tratamento farmacológico , Complicações Infecciosas na Gravidez/tratamento farmacológico , Adolescente , Adulto , Varicela/complicações , Terapia Combinada , Quimioterapia Combinada , Feminino , Humanos , Recém-Nascido , Pneumonia Viral/etiologia , Respiração com Pressão Positiva , Gravidez , Complicações Infecciosas na Gravidez/etiologiaRESUMO
Meteneprost potassium, a PGE2 analogue, was evaluated in thirty non-pregnant women for use as a prospective cervical dilator and softening agent. No significant change in cervical dilation was noted. A significant relationship between obesity and side effects was observed.
