RESUMO
BACKGROUND: Atopic dermatitis is a severe chronic skin disease often deteriorated by the presence of microorganisms and often responds well to treatment with potent corticosteroids. However, the long-term use of potent topical corticosteroids are accompanied by side-effects such as skin atrophy. OBJECTIVE: To study the effect and safety of prophylactic treatment with mometasone furoate fatty cream (contains hexylene glycol) for 6 months in patients with atopic dermatitis. RESULTS: Sixty-one of 68 (90%) patients were still free of their disease after 6 months of twice weekly treatment and only one showed possible treatment related signs of skin atrophy. The number of Staphylococcus aureus and Pityrosporum ovale were significantly reduced in cleared patients. CONCLUSIONS: Mometasone furoate fatty cream is effective and safe both for treatment and as a prophylaxis in patients with atopic dermatitis.
Assuntos
Anti-Inflamatórios/uso terapêutico , Dermatite Atópica/tratamento farmacológico , Pregnadienodiois/uso terapêutico , Administração Tópica , Adulto , Anti-Inflamatórios/administração & dosagem , Dermatite Atópica/microbiologia , Esquema de Medicação , Feminino , Glucocorticoides , Humanos , Masculino , Furoato de Mometasona , Pregnadienodiois/administração & dosagem , Segurança , Fatores de TempoRESUMO
The analgesic effect of a lidocaine/prilocaine cream (EMLA) for the curettage of molluscum contagiosum was evaluated in 55 children aged 3-14 years. Five to 25 molluscs per child were covered with a maximum of 10 g EMLA cream one hour before the operation. The pain was rated as either none or slight by 93% of the children while the physician's assessment was 96%. On a 100 mm Visual Analogue Scale (VAS) where 0 represented no pain and 100 severe pain, the median rating by the children was 3 mm. Mild vasoreactions such as pallor, redness or oedema were observed locally at the treated skin areas. The results show that EMLA cream provided effective local anaesthesia for the curettage of molluscs.
Assuntos
Analgesia , Lidocaína/uso terapêutico , Molusco Contagioso/terapia , Prilocaína/uso terapêutico , Administração Cutânea , Adolescente , Criança , Pré-Escolar , Curetagem , Feminino , Humanos , Masculino , Dor/prevenção & controleRESUMO
Chlamydia trachomatis was isolated by the irradiated McCoy cell technique from 44 out of 103 men with non-gonorrhoeic urethritis and from 11 out of 15 patients with post-gonococcal urethritis. In women attending the venereal diseases clinics, chlamydial infection was observed in 49 out of 130 patients (38%), an infection incidence of the same order of magnitude as the one noted for gonococcal infection (40%). In 19% both infections occurred simultaneously. Treatment with tetracycline eliminated symptoms and chlamydial infection in almost all cases. The significance of the findings is discussed.
